ACOTA MR TAB

Overview

ACOTA MR TAB is a Schedule H drug.

ACOTA MR TAB is composed of: ACECLOFENAC ( ), PARACETAMOL ( ), TIZANIDINE ( )

Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) with analgesic properties. Aceclofenac potently inhibits the cyclo-oxygenase enzyme (COX) that is involved in the synthesis of prostaglandins, which are inflammatory mediators that cause pain, swelling, inflammation, and fever.  It is orally administered for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.

Paracetamol is a pain reliever and a fever reducer. The exact mechanism of action of is not known. Paracetamol is used to treat many conditions such as a headache, muscle aches, arthritis, backache, toothaches, colds, and fevers. It relieves pain in mild arthritis but has no effect on the underlying inflammation and swelling of the joint.

Tizanidine is a short-acting muscle relaxer. It works by blocking nerve impulses (pain sensations) that are sent to your brain. Tizanidine is used to treat spasticity by temporarily relaxing muscle tone.

Usage

ACECLOFENAC is generally used to treat: Osteoarthritis, Rheumatoid Arthritis, Ankylosing Spondylitis

PARACETAMOL is generally used to treat: Arthritis
PARACETAMOL can address symptoms like: Head Headache, Back Pain, Cold, Fever

TIZANIDINE is generally used to treat: Spasticity

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 1month

Q: Can it be taken during pregnancy?
A: Not enough studies to prove Risk – Ask your Doctor

Q: Is it safe to take for someone breastfeeding?
A: Not Safe

How Do I Take It?

ACOTA MR TAB is generally taken With Food.

Precautions for ACOTA MR TAB and its Constituents

• if the stools in black or blood consult your doctor.
• not fully safe to take while pregnant and breastfeeding.
• swallow the tablet whole with aglass of water do not crush or chew the tablets.

Caution should be exercised in patients with history of asthma, bleeding problems, growths in the nose, heart, kidney or liver disease, liver inflammation, high blood pressure, chickenpox, anxiety, trouble in sleeping, ulcers, stomach problems, stroke, Kawasaki syndrome, any allergy, who are taking other medications, during pregnancy and breastfeeding. Avoid alcohol consumption. It should not be used in children with infections such as flu, chickenpox or viral infections. Avoid large amount of caffeinated beverages while taking this medication. It may reduce platelet counts; avoid injury or bruising.
Caution should be exercised in patients with history of prolonged QT interval, liver or kidney disease, children, elderly, pregnancy and breastfeeding. Monitor LFT(Liver Function test) regularly. Stop treatment if liver enzymes are raised persistently greater than 3 times upper limit of normal range. Avoid abrupt withdrawal of therapy. It may make you drowsy. Do not drive a car or operate machinery while taking this medication.

Symptoms of Overdosage

ACECLOFENAC over-dosage can result in: Abdomen Pain, Nausea, Head Headache, Dizziness, Drowsiness
PARACETAMOL over-dosage can result in: Loss Of Appetite, Nausea, Vomit, Abdomen Pain, Weakness (generalized), Upper Abdomen Pain, Dark Colored (brown) Urine, Eyes Yellow Eyes
TIZANIDINE over-dosage can result in: Weakness (generalized), Drowsiness, Confusion, Slow Heart Rate (pulse), Slow Or Irregular Breathing, Lightheadedness, Fainting

Common Side-Effects

ACECLOFENAC : Osteoarthritis, Rheumatoid Arthritis, Ankylosing Spondylitis, Head Headache, Nausea, Vomit, Drowsiness, Dizziness
TIZANIDINE : Dry Mouth, Constipation, Fatigue (tiredness)

Serious Side-Effects

ACECLOFENAC : Black (tar) Colored Stools, Bloody Or Red Colored Stools, Wheezing
TIZANIDINE : Irregular Heartbeat, Hallucinations, Eyes Blurred Vision

Rare Side-Effects

PARACETAMOL : Skin Rash, Dizziness, Difficulty Breathing, Face Swelling, Body Itching
TIZANIDINE : Skin Rash, Difficulty Breathing, Face Swelling, Body Itching

Disease Interactions

TIZANIDINE can interfere with: Acute Liver Failure, Hypotension, Acute Renal Failure, Psychosis

Technical Classification

ACECLOFENAC is categorized as: NONSTEROIDAL ANTI-INFLAMMATORY AGENTS / ANALGESICS / CENTRAL NERVOUS SYSTEM AGENTS
PARACETAMOL is categorized as: MISCELLANEOUS ANALGESICS / ANALGESICS / CENTRAL NERVOUS SYSTEM AGENTS
TIZANIDINE is categorized as: SKELETAL MUSCLE RELAXANTS / MUSCLE RELAXANTS / CENTRAL NERVOUS SYSTEM AGENTS

Available Alternatives for ACOTA MR TAB

What are the commonly available Substitutes?

ACENOVA TAB MR	INR 50 for 10 TABLET MR	ACECLOFENAC , PARACETAMOL , TIZANIDINE
ACOTA MR TAB	INR 39.95 for 10 TABLET MR	ACECLOFENAC , PARACETAMOL , TIZANIDINE

What are the other drugs with similar Ingredients?

ACCETIZ P 100MG/500MG/2MG TAB	INR 57.1 for 10 TABLETS	PARACETAMOL 500.0 MG, ACECLOFENAC 100.0 MG, TIZANIDINE 2.0 MG
ACICLOFLEX 100MG/500MG/2MG TAB MR	INR 53 for 10 TABLET MR	PARACETAMOL 500.0 MG, ACECLOFENAC 100.0 MG, TIZANIDINE 2.0 MG
ASFLAM TAB	INR 48.61 for 10 TABLETS	PARACETAMOL , TIZANIDINE , SERRATIOPEPTIDASE , ACECLOFENAC
KINECTINE MR TAB	INR 55.95 for 10 TABLET MR	PARACETAMOL 500.0 MG, ACECLOFENAC 100.0 MG, TIZANIDINE 2.0 MG
MOVON-MR 100MG/500MG/2MG TAB	INR 65 for 10 TABLETS	PARACETAMOL 500.0 MG, ACECLOFENAC 100.0 MG, TIZANIDINE 2.0 MG
VALDONE MR 100MG/500MG/2MG TAB	INR 42 for 10 TABLET MR	PARACETAMOL 500.0 MG, ACECLOFENAC 100.0 MG, TIZANIDINE 2.0 MG