BRUFEN MR 400MG/2MG CAP

Overview

BRUFEN MR 400MG/2MG CAP is a Schedule H drug.

BRUFEN MR 400MG/2MG CAP is composed of: IBUPROFEN (400.0 MG), TIZANIDINE (2.0 MG)

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body. Ibuprofen is used to reduce fever and treat pain or inflammation caused by many conditions such as a headache, toothache, back pain, arthritis, menstrual cramps, or minor injury. This medicine can be used in children and adolescents of all ages.

Tizanidine is a short-acting muscle relaxer. It works by blocking nerve impulses (pain sensations) that are sent to your brain. Tizanidine is used to treat spasticity by temporarily relaxing muscle tone.

Usage

IBUPROFEN is generally used to treat: Arthritis
IBUPROFEN can address symptoms like: Head Headache, Back Pain

TIZANIDINE is generally used to treat: Spasticity

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 6month

Q: Can it be taken during pregnancy?
A: Not enough studies to prove Risk – Ask your Doctor

Q: Is it safe to take for someone breastfeeding?
A: Not Safe

Precautions for BRUFEN MR 400MG/2MG CAP and its Constituents

Caution should be exercised in patients with high blood pressure, blood disorders, bleeding problem, heart disease, blood vessel disease, asthma, nose polyps, kidney or liver disease, diabetes, dehydration, alcohol abuse, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding. It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication. It may cause stomach bleeding or ulcer; if it so consult with your doctor. Avoid alcohol consumption.
Caution should be exercised in patients with history of prolonged QT interval, liver or kidney disease, children, elderly, pregnancy and breastfeeding. Monitor LFT(Liver Function test) regularly. Stop treatment if liver enzymes are raised persistently greater than 3 times upper limit of normal range. Avoid abrupt withdrawal of therapy. It may make you drowsy. Do not drive a car or operate machinery while taking this medication.

Symptoms of Overdosage

IBUPROFEN over-dosage can result in: Nausea, Vomit, Abdomen Pain, Drowsiness, Black (tar) Colored Stools, Bloody Or Red Colored Stools, Slow Or Irregular Breathing, Fainting
TIZANIDINE over-dosage can result in: Weakness (generalized), Drowsiness, Confusion, Slow Heart Rate (pulse), Slow Or Irregular Breathing, Lightheadedness, Fainting

Common Side-Effects

IBUPROFEN : Diarrhoea, Head Headache, Abdomen Upset Stomach, Constipation
TIZANIDINE : Dry Mouth, Constipation, Fatigue (tiredness)

Serious Side-Effects

IBUPROFEN : Heart Failure, Easy Bruising, Mood Swings, Fatigue (tiredness), Weight Gain
TIZANIDINE : Irregular Heartbeat, Hallucinations, Eyes Blurred Vision

Rare Side-Effects

IBUPROFEN : Skin Rash, Body Itching, Face Swelling, Difficulty Breathing
TIZANIDINE : Skin Rash, Difficulty Breathing, Face Swelling, Body Itching

Disease Interactions

TIZANIDINE can interfere with: Acute Liver Failure, Hypotension, Acute Renal Failure, Psychosis

Technical Classification

TIZANIDINE is categorized as: SKELETAL MUSCLE RELAXANTS / MUSCLE RELAXANTS / CENTRAL NERVOUS SYSTEM AGENTS

Available Alternatives for BRUFEN MR 400MG/2MG CAP

What are the commonly available Substitutes?

BRUFEN MR 400MG/2MG CAP	INR 18.5 for 10 CAPSULES	IBUPROFEN 400.0 MG, TIZANIDINE 2.0 MG
BRUFEN MR CAP	INR 18.5 for 10 CAPSULES	IBUPROFEN 400 MG, TIZANIDINE 2 MG
LUMBRIL TAB	INR 20.58 for 10 TABLETS	IBUPROFEN 400.0 MG, TIZANIDINE 2.0 MG
TIZAFEN 400MG/2MG CAP	INR 67.92 for 10 CAPSULES	IBUPROFEN 400.0 MG, TIZANIDINE 2.0 MG
TIZAPAM 400MG/2MG TAB	INR 53 for 10 TABLETS	IBUPROFEN 400.0 MG, TIZANIDINE 2.0 MG