COFLAM MR 400MG/325MG/250MG TAB

Overview

COFLAM MR 400MG/325MG/250MG TAB is a Schedule H drug.

COFLAM MR 400MG/325MG/250MG TAB is composed of: IBUPROFEN (400.0 MG), PARACETAMOL (325.0 MG), CHLORZOXAZONE (250.0 MG)

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body. Ibuprofen is used to reduce fever and treat pain or inflammation caused by many conditions such as a headache, toothache, back pain, arthritis, menstrual cramps, or minor injury. This medicine can be used in children and adolescents of all ages.

Paracetamol is a pain reliever and a fever reducer. The exact mechanism of action of is not known. Paracetamol is used to treat many conditions such as a headache, muscle aches, arthritis, backache, toothaches, colds, and fevers. It relieves pain in mild arthritis but has no effect on the underlying inflammation and swelling of the joint.

Chlorzoxazone is a muscle relaxer that blocks pain sensations between the nerves and the brain.Chlorzoxazone is used together with rest and physical therapy to treat skeletal muscle conditions such as pain or injury.Chlorzoxazone is used for muscle relaxation. It relieves painful spasms of the skeletal muscles.Chlorzoxazone is a muscle relaxant. It works on the centres in the brain and spinal cord to relieve muscle stiffness or spasm without reduction in strength. This improves pain and movement of muscles.It is usually used along with rest, physical therapy, and other treatment. It works by helping to relax the muscles.

Usage

IBUPROFEN is generally used to treat: Arthritis
IBUPROFEN can address symptoms like: Head Headache, Back Pain

PARACETAMOL is generally used to treat: Arthritis
PARACETAMOL can address symptoms like: Head Headache, Back Pain, Cold, Fever

CHLORZOXAZONE is generally used to treat: Muscle Pain

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 1month

Q: Can it be taken during pregnancy?
A: Not enough studies to prove Risk – Ask your Doctor

Q: Is it safe to take for someone breastfeeding?
A: Not Safe

Precautions for COFLAM MR 400MG/325MG/250MG TAB and its Constituents

Caution should be exercised in patients with high blood pressure, blood disorders, bleeding problem, heart disease, blood vessel disease, asthma, nose polyps, kidney or liver disease, diabetes, dehydration, alcohol abuse, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding. It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication. It may cause stomach bleeding or ulcer; if it so consult with your doctor. Avoid alcohol consumption.
Caution should be exercised in patients with history of asthma, bleeding problems, growths in the nose, heart, kidney or liver disease, liver inflammation, high blood pressure, chickenpox, anxiety, trouble in sleeping, ulcers, stomach problems, stroke, Kawasaki syndrome, any allergy, who are taking other medications, during pregnancy and breastfeeding. Avoid alcohol consumption. It should not be used in children with infections such as flu, chickenpox or viral infections. Avoid large amount of caffeinated beverages while taking this medication. It may reduce platelet counts; avoid injury or bruising.

• Chlorzoxazone can increase the effects of other CNS depressants (alcohol, barbiturates) medicine.
• Avoid consuming alcohol when taking the Chlorzoxazone, as it may cause excessive drowsiness and calmness.
• Inform your doctor if you have ever been diagnosed with kidney or liver problems.
• Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
• Follow all directions on your medicine label and package.You should not use chlorzoxazone if you are allergic to it.
• Follow all directions on your prescription label. Your doctor may occasionally change your dose.
• Do not use this medicine in larger or smaller amounts or for longer than recommended.
• Chlorzoxazone is usually taken 3 or 4 times per day.
• Chlorzoxazone is only part of a complete program of treatment that may also include rest, physical therapy, or other pain relief measures.
• Follow your doctor’s instructions.Caution needed for patients with history of allergic reactions, liver disease, pregnancy and breastfeeding.
• Do not drink alcohol while taking this medication.
• Monitor liver function regularly.

Symptoms of Overdosage

IBUPROFEN over-dosage can result in: Nausea, Vomit, Abdomen Pain, Drowsiness, Black (tar) Colored Stools, Bloody Or Red Colored Stools, Slow Or Irregular Breathing, Fainting
PARACETAMOL over-dosage can result in: Loss Of Appetite, Nausea, Vomit, Abdomen Pain, Weakness (generalized), Upper Abdomen Pain, Dark Colored (brown) Urine, Eyes Yellow Eyes
CHLORZOXAZONE over-dosage can result in: Nausea, Vomit, Drowsiness, Fainting, Slow Or Irregular Breathing

Common Side-Effects

IBUPROFEN : Diarrhoea, Head Headache, Abdomen Upset Stomach, Constipation
CHLORZOXAZONE : Weakness (generalized), Dizziness, Drowsiness, Abdomen Upset Stomach, Lightheadedness

Serious Side-Effects

IBUPROFEN : Heart Failure, Easy Bruising, Mood Swings, Fatigue (tiredness), Weight Gain
CHLORZOXAZONE : Skin Rash, Itchy Skin, Jaundice, Abdomen Pain, Loss Of Appetite, Fever, Dark Colored (brown) Urine, Black (tar) Colored Stools, Bloody Or Red Colored Vomit

Rare Side-Effects

IBUPROFEN : Skin Rash, Body Itching, Face Swelling, Difficulty Breathing
PARACETAMOL : Skin Rash, Dizziness, Difficulty Breathing, Face Swelling, Body Itching
CHLORZOXAZONE : Hives, Dizziness, Constipation, Cough, Decreased Appetite, Difficulty Swallowing, Rapid Heart Rate (pulse), Head Headache, Shortness Of Breath, Face Swelling, Hands Swelling, Feet Swelling, Legs Swelling, Swollen Lips, Pale Skin

Disease Interactions

CHLORZOXAZONE can interfere with: Acute Liver Failure

Technical Classification

PARACETAMOL is categorized as: MISCELLANEOUS ANALGESICS / ANALGESICS / CENTRAL NERVOUS SYSTEM AGENTS
CHLORZOXAZONE is categorized as: SKELETAL MUSCLE RELAXANTS / MUSCLE RELAXANTS / CENTRAL NERVOUS SYSTEM AGENTS

Available Alternatives for COFLAM MR 400MG/325MG/250MG TAB

What are the commonly available Substitutes?

COFLAM MR 400MG/325MG/250MG TAB	INR 35 for 10 TABLET MR	IBUPROFEN 400.0 MG, PARACETAMOL 325.0 MG, CHLORZOXAZONE 250.0 MG
DOLOMED-MR TAB	INR 11.4 for 10 TABLETS	IBUPROFEN 400 MG, PARACETAMOL 325 MG, CHLORZOXAZONE 250 MG
FLEXON -MR TAB	INR 15.35 for 10 TABLETS	IBUPROFEN 400 MG, PARACETAMOL 325 MG, CHLORZOXAZONE 250 MG
MEGAFLAM M R 400MG/325MG/250MG TAB	INR 36.8 for 10 TABLETS	IBUPROFEN 400.0 MG, PARACETAMOL 325.0 MG, CHLORZOXAZONE 250.0 MG
SYSDOL MR 400MG/325MG/250MG TAB	INR 53.25 for 10 TABLET MR	IBUPROFEN 400.0 MG, PARACETAMOL 325.0 MG, CHLORZOXAZONE 250.0 MG

What are the other drugs with similar Ingredients?

ARTIFLEX PLUS 400MG/300MG/250MG TAB	INR 27 for 10 TABLETS	IBUPROFEN 400.0 MG, PARACETAMOL 300.0 MG, CHLORZOXAZONE 250.0 MG
SPONTREL TAB	INR 8.1 for 10 TABLETS	IBUPROFEN 400.0 MG, PARACETAMOL 300.0 MG, CHLORZOXAZONE 250.0 MG