COMBIDIN 325MG/30MG/400MG TAB

Overview

COMBIDIN 325MG/30MG/400MG TAB is a Schedule H drug.

COMBIDIN 325MG/30MG/400MG TAB is composed of: IBUPROFEN (400.0 MG), PARACETAMOL (325.0 MG), CODEINE (30.0 MG)

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body. Ibuprofen is used to reduce fever and treat pain or inflammation caused by many conditions such as a headache, toothache, back pain, arthritis, menstrual cramps, or minor injury. This medicine can be used in children and adolescents of all ages.

Paracetamol is a pain reliever and a fever reducer. The exact mechanism of action of is not known. Paracetamol is used to treat many conditions such as a headache, muscle aches, arthritis, backache, toothaches, colds, and fevers. It relieves pain in mild arthritis but has no effect on the underlying inflammation and swelling of the joint.

Codeine is an opioid pain medication, sometimes called a narcotic.Codeine is used to treat mild to moderately severe pain.Codeine is used for moderate to severe pain and dry cough.It works by decreasing the perception of pain by blocking the transmission of pain signals to the brain.

Usage

IBUPROFEN is generally used to treat: Arthritis
IBUPROFEN can address symptoms like: Head Headache, Back Pain

PARACETAMOL is generally used to treat: Arthritis
PARACETAMOL can address symptoms like: Head Headache, Back Pain, Cold, Fever

CODEINE is generally used to treat: Pain

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 1month

Q: Can it be taken during pregnancy?
A: Not enough studies to prove Risk – Ask your Doctor

Q: Is it safe to take for someone breastfeeding?
A: Not Safe

Precautions for COMBIDIN 325MG/30MG/400MG TAB and its Constituents


Caution should be exercised in patients with high blood pressure, blood disorders, bleeding problem, heart disease, blood vessel disease, asthma, nose polyps, kidney or liver disease, diabetes, dehydration, alcohol abuse, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding. It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication. It may cause stomach bleeding or ulcer; if it so consult with your doctor. Avoid alcohol consumption.
Caution should be exercised in patients with history of asthma, bleeding problems, growths in the nose, heart, kidney or liver disease, liver inflammation, high blood pressure, chickenpox, anxiety, trouble in sleeping, ulcers, stomach problems, stroke, Kawasaki syndrome, any allergy, who are taking other medications, during pregnancy and breastfeeding. Avoid alcohol consumption. It should not be used in children with infections such as flu, chickenpox or viral infections. Avoid large amount of caffeinated beverages while taking this medication. It may reduce platelet counts; avoid injury or bruising.
  • Use Codeine as instructed by your doctor. Never take in greater amounts or more often than prescribed.
  • It causes sleepiness or drowsiness. If this happens to you, do not drive or use machinery.Avoid consuming alcohol when taking the Codeine, as it may cause excessive sleepiness or drowsiness.
  • Inform your doctor if you have ever been diagnosed with kidney or liver problems.
  • Store opioid pain relievers in a safe place and out of reach of others.
  • You should not use codeine if you have severe breathing problems, a blockage in your stomach or intestines, or frequent asthma attacks or hyperventilation.
  • You should not use this medicine if you are allergic to it,Take codeine exactly as prescribed by your doctor.
  • Follow all directions on your prescription label. Codeine can slow or stop your breathing. Never use this medicine in larger amounts, or for longer than prescribed.
  • Tell your doctor if the medicine seems to stop working as well in relieving your pain.
  • Codeine may be habit-forming, even at regular doses. Never share this medicine with another person, especially someone with a history of drug abuse or addiction.
  • Take this medicine with food or milk if it upsets your stomach.
  • Drink 6 to 8 full glasses of water daily to help prevent constipation while you are taking this medicine.
  • Do not use a stool softener (laxative) without first asking your doctor.
  • Do not stop using codeine suddenly after long-term use, or you could have unpleasant withdrawal symptoms.

Symptoms of Overdosage

IBUPROFEN over-dosage can result in: Nausea, Vomit, Abdomen Pain, Drowsiness, Black (tar) Colored Stools, Bloody Or Red Colored Stools, Slow Or Irregular Breathing, Fainting
PARACETAMOL over-dosage can result in: Loss Of Appetite, Nausea, Vomit, Abdomen Pain, Weakness (generalized), Upper Abdomen Pain, Dark Colored (brown) Urine, Eyes Yellow Eyes
CODEINE over-dosage can result in: Slow Heart Rate (pulse), Slow Or Irregular Breathing, Drowsiness

Common Side-Effects

IBUPROFEN : Diarrhoea, Head Headache, Abdomen Upset Stomach, Constipation
CODEINE : Constipation, Dizziness, Nausea, Vomit, Lightheadedness, Head Headache

Serious Side-Effects

IBUPROFEN : Heart Failure, Easy Bruising, Mood Swings, Fatigue (tiredness), Weight Gain
CODEINE : Fainting, Seizure, Indigestion, Heartburn, Drowsiness, Depressed Mood, Confusion, Hallucinations, Abdomen Pain, Difficulty Urinating, Eyes Blurred Vision, Irregular Heartbeat, Loss Of Appetite, Fatigue (tiredness)

Rare Side-Effects

IBUPROFEN : Skin Rash, Body Itching, Face Swelling, Difficulty Breathing
PARACETAMOL : Skin Rash, Dizziness, Difficulty Breathing, Face Swelling, Body Itching
CODEINE : Skin Rash, Itchy Skin, Breathlessness

Disease Interactions

CODEINE can interfere with: Acute Liver Failure, Diarrhoea, Alcoholism, Premature Aging, Acute Renal Failure, Hypotension, Respiratory Failure, Adrenal Insufficiency, Hypothyroidism, Seizure, Urinary Retention, Heart Arrhythmias

Technical Classification

PARACETAMOL is categorized as: MISCELLANEOUS ANALGESICS / ANALGESICS / CENTRAL NERVOUS SYSTEM AGENTS
CODEINE is categorized as:
  • NARCOTIC ANALGESICS / ANALGESICS / CENTRAL NERVOUS SYSTEM AGENTS
  • ANTITUSSIVES / RESPIRATORY AGENTS

Available Alternatives for COMBIDIN 325MG/30MG/400MG TAB

What are the commonly available Substitutes?

COMBIDIN 325MG/30MG/400MG TABINR 556.25 for 10 TABLETSIBUPROFEN 400.0 MG, PARACETAMOL 325.0 MG, CODEINE 30.0 MG