ENDOTHIK ES 1MG/25MG CAP

Overview

ENDOTHIK ES 1MG/25MG CAP is a Schedule H drug.

ENDOTHIK ES 1MG/25MG CAP is composed of: SILDENAFIL (25.0 MG), ESTRADIOL (1.0 MG)

Sildenafil relaxes muscles found in the walls of blood vessels and increases blood flow to particular areas of the body. Sildenafil is used to treat erectile dysfunction (impotence) in men. Sildenafil is used to treat pulmonary arterial hypertension and improve exercise capacity in men and women.

Estradiol is a form of estrogen, a female sex hormone that regulates many processes in the body.Estradiol is used to treat menopause symptoms such as hot flashes and vaginal changes, and to prevent osteoporosis (bone loss) in menopausal women.Estradiol is used for hormone replacement therapy and post menopausal osteoporosis.Estradiol is a form of estrogen, a female sex hormone produced by the ovaries. It acts by replacing the natural hormone in the body when the latter is deficient.

Usage

SILDENAFIL is generally used to treat: Impotence, Hypertension

ESTRADIOL is generally used to treat: Menopause, Osteoporosis
ESTRADIOL can address symptoms like: Hot Flashes, Vaginal Dryness

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Check with your Doctor first

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 18yrs

Q: Can it be taken during pregnancy?
A: Considered as Generally Safe – not enough studies to prove risk

Precautions for ENDOTHIK ES 1MG/25MG CAP and its Constituents

Caution needed when used in patients with anatomical deformation of penis or conditions that may predispose them to priapism i.e. painful persistent erection of the penis (e.g. sickle cell anaemia, myeloma, or leukaemia). Mild, transient, dose-related impairment of colour discrimination (blue/green) may occur. May cause liver or severe kidney impairment, bleeding disorders, active peptic ulceration, low blood pressure, recent history of stroke, heart attack, abnormal heart rhythm, chest pain, heart failure, increased blood glucose or retinal disorders. May cause sudden loss or decrease in hearing.

• Do not use estradiol patches over breast stop taking estradiol and see a doctor immediately if you notice any of the following when taking estradiol:
• yellowing of your skin or the whites of your eyes (jaundice). rise in your blood pressure (symptoms may be headache, tiredness, dizziness).new onset migraine-like headaches.
• signs of a blood clot, such as: painful swelling and redness of the legs, sudden chest pain, difficulty in breathing.
• Do not consider estradiol alone as a contraceptive. It must be used with progestogen to provide contraceptive benefits.
• Consult your doctor if you have unusual vaginal bleeding while taking this drug, Immediately consult your doctor if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain, severe headache, or changes in vision. This medicine should not be taken for a very long period.Consult your doctor from time to time to check if you still need it.
• Do not smoke or use tobacco. Estrogens combined with smoking further increases your risk of stroke, blood clots, high blood pressure, and heart attack, especially in women older than 35.
• Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors.If you are nearsighted or wear contact lenses, you may develop vision problems or trouble wearing your contact lenses.

Symptoms of Overdosage

ESTRADIOL over-dosage can result in: Vagina Bleeding, Nausea, Vomit, Dizziness, Drowsiness, Fatigue (tiredness), Abdomen Pain

Common Side-Effects

SILDENAFIL : Edema, Dizziness, Lightheadedness, Head Headache, Abdomen Upset Stomach, Difficulty Sleeping, Hands Swelling, Eyes Blurred Vision
ESTRADIOL : Vaginal Candidiasis, Diarrhoea, Edema, Body Pain, Chills, Cough, Loss Of Voice, Nasal Congestion, Runny Nose, Sneezing, Throat Soreness, Head Headache, Mood Swings, Abdomen Pain, Nausea

Serious Side-Effects

SILDENAFIL : Slow Or Irregular Breathing, Fainting
ESTRADIOL : Jaundice, Vagina Discharge Or Mucus, Weight Gain, Increased Thirst, Frequent Urination, Ankles Swelling, Vaginal Odor, Hands Swelling

Rare Side-Effects

SILDENAFIL : Skin Rash, Dizziness, Difficulty Breathing, Body Itching
ESTRADIOL : BLOOD CLOT, Deep Vein Thrombosis, Pulmonary Embolism, Heart Attack, Stroke, Chest Pain, Jaws Pain, Left Arm Pain, Legs Swelling, Legs Tingling, Difficulty Breathing, Fainting

Disease Interactions

ESTRADIOL can interfere with: Vaginal Discharge, Hypercalcaemia, Hypertension, Thromboembolism, Liver Neoplasms, Angioedema, Gall Bladder Disease, Hyperlipidemia, Acute Liver Failure, Melasma, Depression, Impaired Glucose Tolerance

Technical Classification

SILDENAFIL is categorized as:

• AGENTS FOR PULMONARY HYPERTENSION / CARDIOVASCULAR AGENTS
• IMPOTENCE AGENTS / GENITOURINARY TRACT AGENTS

ESTRADIOL is categorized as: ESTROGENS / SEX HORMONES / HORMONES

Available Alternatives for ENDOTHIK ES 1MG/25MG CAP

What are the commonly available Substitutes?

ALIVHER ES 1MG/25MG TAB	INR 199 for 10 TABLETS	SILDENAFIL 25.0 MG, ESTRADIOL 1.0 MG
ALIVHER ES TAB	INR 199 for 10 TABLETS	SILDENAFIL 25 MG, ESTRADIOL 1 MG
ENDOTHIK ES 1MG/25MG CAP	INR 199 for 10 CAPSULES	SILDENAFIL 25.0 MG, ESTRADIOL 1.0 MG

What are the other drugs with similar Ingredients?

ENDONORM TAB	INR 220 for 10 TABLETS	SILDENAFIL , ESTRADIOL
ENDOTHIK ES 2MG/25MG TAB	INR 225 for 10 TABLETS	SILDENAFIL 25.0 MG, ESTRADIOL 2.0 MG
PRIMIWAL 2MG/25MG TAB	INR 230 for 10 TABLETS	SILDENAFIL 25.0 MG, ESTRADIOL 2.0 MG
PROSTIUM ES CAP	INR 349 for 14 CAPSULES	SILDENAFIL 25 MG, ESTRADIOL 2 MG
PROSTIUM ES CAPULE	INR 349 for 14 CAPSULES	SILDENAFIL 25.0 MG, ESTRADIOL 2.0 MG