FLUBIGAT 0.3MG/3MG EYE DPS

Overview

FLUBIGAT 0.3MG/3MG EYE DPS is a Schedule H drug.

FLUBIGAT 0.3MG/3MG EYE DPS is composed of: GEFITINIB (3.0 MG), FLURBIPROFEN (0.3 MG)

Gefitinib is used to treat non-small cell lung cancer. Gefitinib is a cancer medication that interferes with the growth and spread of cancer cells in the body. Gefitinib belongs to a group of drugs called epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors.

Flurbiprofen is a non-steroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation. It may be taken with food to decrease stomach upset. Flurbiprofen is a prescription medication used to treat the symptoms of osteoarthritis and rheumatoid arthritis. It is also used in liquid form to prevent or reduce changes in the eye that can occur during eye surgery.

Usage

GEFITINIB is generally used to treat: Lung Cancer

FLURBIPROFEN is generally used to treat: Osteoarthritis, Rheumatoid Arthritis

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Ask your doctor

Q: Can it be taken during pregnancy?
A: Studies indicate Risk – Doctor advice is must

Q: Is it safe to take for someone breastfeeding?
A: Not Safe

How Do I Take It?

FLUBIGAT 0.3MG/3MG EYE DPS is generally taken With Food.

Precautions for FLUBIGAT 0.3MG/3MG EYE DPS and its Constituents

• Before using this medication, ask your doctor or pharmacist about your medical history, especially of lung disease, severe kidney disease, eye problems, stomach/intestinal ulcers, other stomach/intestinal problems, smoking, cancer that has spread to the bowels.
• Do not take gefitinib if you are allergic to any of its ingredients.
• Before starting gefitinib treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.).   Do not take aspirin, or products containing aspirin unless your doctor specifically permits this.
• Do not receive any kind of immunization or vaccination without your doctor’s approval while taking gefitinib.
• For both men and women: Do not conceive a child (get pregnant) while taking gefitinib. Barrier methods of contraception, such as condoms, are recommended. Discuss with your doctor when you may safely become pregnant or conceive a child after therapy.

• This medication comes in tablet form and is taken up to 4 times a day with or without food. It is also available as an eye drop, and is usually instilled every 30 minutes beginning 2 hours before surgery, for a total of 4 doses.
• This medicine may cause stomach bleeding. Daily use of alcohol and tobacco, especially when combined with this medicine, may increase your risk for stomach bleeding. Limit alcohol and stop smoking.
• This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors.
• Older adults may be more sensitive to the side effects of this drug, especially stomach/intestinal bleeding, kidney problems, and worsening heart problems.
• Tell your doctor if you are pregnant or if you plan to become pregnant. During pregnancy, this medication should be used only when clearly needed. It is not recommended for use during the first and last trimesters of pregnancy due to possible harm to the unborn baby and interference with normal labor/delivery.
• This drug passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.
• Before taking flurbiprofen, tell your doctor or pharmacist if you are allergic to it or to aspirin or other NSAIDs (e.g., ibuprofen, naproxen, celecoxib).
• This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have aspirin-sensitive asthma (a history of worsening breathing with runny/stuffy nose after taking aspirin or other NSAIDs), recent heart bypass surgery (CABG).

Symptoms of Overdosage

FLURBIPROFEN over-dosage can result in: Abdomen Pain, Vomit, Drowsiness, Slow Or Irregular Breathing

Common Side-Effects

GEFITINIB : Eyes Burning Sensation, Chest Pain, Chills, Cough, Difficulty Breathing, Eyes Dry Eyes, Shortness Of Breath
FLURBIPROFEN : Abdomen Pain, Black (tar) Colored Stools, Constipation, Difficulty Urinating, Lower Back Pain

Serious Side-Effects

GEFITINIB : Abdomen Pain, Dark Colored (brown) Urine, Decreased Appetite, Fever, Nausea, Vomit
FLURBIPROFEN : Stomach Pain, Abdomen Pain, Bloody Or Red Colored Vomit, Bloody Or Red Colored Stools, Irregular Heartbeat

Rare Side-Effects

GEFITINIB : Bloody Or Red Colored Stools, Eyes Redness, Eyes Eye Irritation, Heartburn, Abdomen Pain, Throat Soreness, Vomit
FLURBIPROFEN : Back Pain, Gums Bleeding, Loose Motion, Eyes Blurred Vision, Chest Pain, Chills, Cough, Dark Colored (brown) Urine, Difficulty Breathing, Difficulty Swallowing, Dizziness, Fatigue (tiredness), Irregular Heartbeat, Fainting, Lightheadedness, Head Headache, Fever, Body Itching, Increased Thirst, Slow Heart Rate (pulse), Loss Of Appetite, Nausea, Pale Skin, Eyes Eye Irritation, Eyes Swelling, Throat Soreness, Body Excessive Sweating, Vomit, Weight Gain, Weight Loss (unintentional), Eyes Yellow Eyes

Food Interactions

Grapefruit may increase serum product levels.

Disease Interactions

FLURBIPROFEN can interfere with: Asthma, Anemia, Heart Failure, Acute Liver Failure, Hypercalcaemia, Hyperkalemia, Hypertension, Thrombosis

Technical Classification

GEFITINIB is categorized as: EGFR INHIBITORS / ANTINEOPLASTICS
FLURBIPROFEN is categorized as: NONSTEROIDAL ANTI-INFLAMMATORY AGENTS / ANALGESICS / CENTRAL NERVOUS SYSTEM AGENTS

Available Alternatives for FLUBIGAT 0.3MG/3MG EYE DPS

What are the commonly available Substitutes?

FLUBIGAT 0.3MG/3MG EYE DPS	INR 58 for 5 ML EYE DROP	GEFITINIB 3.0 MG, FLURBIPROFEN 0.3 MG
FLURGAT 0.3MG/3MG EYE DPS	INR 71.5 for 5 ML EYE DROP	GEFITINIB 3.0 MG, FLURBIPROFEN 0.3 MG

What are the other drugs with similar Ingredients?

GATIAID F 0.03%/0.3% EYE DPS

INR 72 for 5 ML EYE DROP

FLURBIPROFEN 0.03 %W/V, GEFITINIB 0.3 %W/V