FOURDERM CRM

Overview

FOURDERM CRM is a Schedule H antibiotic.

FOURDERM CRM is composed of: MICONAZOLE (2.0 %W/W), CHLORHEXIDINE (0.2 %W/W), CLOBETASOL PROPIONATE (0.05 %W/W), NEOMYCIN (0.5 %W/W)

Miconazole is an antifungal medicine that fights infections caused by fungus.Miconazole buccal is a pill placed between your check and gum to treat candida (yeast) infections inside the mouth.
It kills fungi by destroying the fungal cell membrane. This treats your infection.


Chlorhexidine is an antiseptic that fights bacteria. Chlorhexidine topical (for the skin) is used to clean the skin to prevent infection that may be caused by surgery, injection or skin injury.

Clobetasol is a highly potent steroid. It reduces the actions of chemicals in the body that cause inflammation. Clobetasol topical (for the skin) is used to treat the inflammation and itching caused by a number of skin conditions such as allergic reactions, eczema, and psoriasis.

Neomycin is an antibiotic that fights bacteria in the body. Neomycin is used to reduce the risk of infection during surgery of your intestines. Neomycin is also used to reduce the symptoms of hepatic coma. Neomycin is an antibiotic used to treat complications of liver disease, and can be used to prepare for abdominal surgery. Neomycin topical cream is used for minor cuts and burns.

Usage

MICONAZOLE is generally used to treat: Fungal Infection, Yeast Infection, Athlete’s Foot, Jock Itch, Vaginal Candidiasis

CHLORHEXIDINE is generally used to treat: Bacterial Infection

CLOBETASOL PROPIONATE is generally used to treat: Eczema, Psoriasis

NEOMYCIN is generally used to treat: Escherichia Coli Infection, Hepatic Encephalopathy, Allergic Skin Disease, Bacterial Infection

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 2month

Q: Can it be taken during pregnancy?
A: Studies indicate Risk – Doctor advice is must

Q: Is it safe to take for someone breastfeeding?
A: Not Safe

Precautions for FOURDERM CRM and its Constituents


  • Follow all directions on your medicine label and package.You should not use this medicine if you are allergic to miconazole (Monistat, Vusion, and others) or if you are allergic to milk proteins.
  • Do not use this medicine in larger or smaller amounts or for longer than recommended.
  • The usual dose of this medicine is one tablet each morning for 14 days in a row.
  • Brush your teeth before putting in a buccal tablet.
  • Make sure your hands are dry before handling the tablet.
  • Do not chew or swallow the buccal tablet. Leave it in place until the next morning.
  • Avoid touching or pressing the tablet while it is in place.
  • You may eat and drink normally while the tablet is in place, but avoid chewing gum.If any pieces of the tablet remain in your mouth the next morning, rinse your mouth with water before using a new tablet.
  • Avoid wearing an upper denture if it gets in the way of the buccal tablet.Do not skip any doses and finish the full course of treatment even if you feel better.
  • Avoid contact with your eyes.

Avoid getting this medicine in your eyes, ears, nose, mouth, rectum, or vagina. If this does happen, rinse with water. Avoid using other medicines on the areas you treat with chlorhexidine topical unless your doctor tells you to. Avoid getting this medicine on your clothing or other fabrics.

Do not use clobetasol topical to treat any condition that has not been checked by your doctor. Avoid using clobetasol topical to treat skin on your face, underarms, or groin area without your doctor’s advice. Avoid getting this medicine in your eyes. If contact does occur, rinse with water. Do not use clobetasol topical on broken or infected skin. Also avoid using this medicine in open wounds.


  • Caution should be exercised in patients with history of kidney disease, any allergy, during pregnancy and breastfeeding.
  • Take neomycin for the full course of treatment. Don’t stop taking the oral form of the medicine without first talking to your doctor.
  • Before using topical neomycin, tell your doctor if you’ve ever had kidney problems or kidney disease.

Symptoms of Overdosage

CLOBETASOL PROPIONATE over-dosage can result in: Easy Bruising

Common Side-Effects

MICONAZOLE : Pain, Diarrhoea, Itchy Skin, Toothache, Abdomen Pain, Loss Of Appetite, Weakness (generalized), Upper Abdomen Pain, Head Headache, Nausea, Dry Mouth, Decreased Taste, Gums Redness, Body Pain, Fever, Chills, Nasal Congestion, Pale Skin, Runny Nose, Sneezing, Throat Soreness, Fatigue (tiredness)
CLOBETASOL PROPIONATE : Excessive Body Hair Growth, Body Itching
NEOMYCIN : Skin Rash, Diarrhoea, Hearing Loss, Loose Motion, Difficulty Breathing, Dizziness, Increased Thirst, Weakness (generalized)

Serious Side-Effects

MICONAZOLE : Difficulty Breathing, Pain With Urination, Tongue Soreness

Rare Side-Effects

MICONAZOLE : Mouth Ulcer, Black (tar) Colored Stools, Shortness Of Breath, Mouth Soreness
CLOBETASOL PROPIONATE : Folliculitis, Skin Rash, Fatigue (tiredness), Weight Loss (unintentional), Head Headache, Ankles Swelling, Increased Thirst, Frequent Urination, Dizziness, Difficulty Breathing, Face Swelling

Disease Interactions

NEOMYCIN can interfere with: Diarrhoea, Vomiting, Botulism, Hypocalcemia, Parkinsonism, Hearing Loss, Tinnitus, Acute Renal Failure, Colitis, Colonic Ischemia

Technical Classification

MICONAZOLE is categorized as: AZOLE ANTIFUNGALS / ANTIFUNGALS / ANTI-INFECTIVES
CHLORHEXIDINE is categorized as:
  • ANTISEPTIC AND GERMICIDES / TOPICAL AGENTS
  • MOUTH AND THROAT PRODUCTS / TOPICAL AGENTS

CLOBETASOL PROPIONATE is categorized as: TOPICAL STEROIDS / DERMATOLOGICAL AGENTS / TOPICAL AGENTS
NEOMYCIN is categorized as: AMINOGLYCOSIDES / ANTI-INFECTIVES

Available Alternatives for FOURDERM CRM

What are the commonly available Substitutes?

FOURDERM CRMINR 139 for 20 GM CREAMMICONAZOLE 2.0 %W/W, CHLORHEXIDINE 0.2 %W/W, CLOBETASOL PROPIONATE 0.05 %W/W, NEOMYCIN 0.5 %W/W

What are the other drugs with similar Ingredients?

EXEL-GN CRMINR 48 for 15 GM CREAMNEOMYCIN 0.5 %W/W, CLOBETASOL PROPIONATE 0.05 %W/W