GLYCOPYROLATE AND NEOSTIGMIN 0.5MG/2.5MG INJ

Overview

GLYCOPYROLATE AND NEOSTIGMIN 0.5MG/2.5MG INJ is a Schedule H drug.

GLYCOPYROLATE AND NEOSTIGMIN 0.5MG/2.5MG INJ is composed of: NEOSTIGMINE (2.5 MG), GLYCOPYRROLATE (0.5 MG)

This medication is a cholinesterase inhibitor, prescribed for Myasthenia Gravis. It inhibits the chemicals, which brings non-communication between the nervous and the muscular system. Neostigmine enhances the muscular movements in case of Myasthenia Gravis condition. 
which help to increase a natural chemical in your body that stimulates muscle movement

Glycopyrrolate reduces the secretions of certain organs in the body. Glycopyrrolate helps to control conditions such as peptic ulcers that involve excessive stomach acid production. This medication is a muscarinic anticholinergic agent. Glycopyrrolate is also used to reduce drooling in children ages 3 to 16 who have certain medical conditions, such as cerebral palsy.

Usage

NEOSTIGMINE is generally used to treat: Myasthenia Gravis, Paralytic Ileus
NEOSTIGMINE can address symptoms like: Arms Weakness, Legs Weakness, Eyes Double Vision (without One Eye Covered), Slurred Speech, Eyes Drooping Eyelid, Shortness Of Breath, Difficulty Swallowing, Fatigue (tiredness), Muffled Voice

GLYCOPYRROLATE is generally used to treat: Peptic Ulcer
GLYCOPYRROLATE can address symptoms like: Abdomen Pain, Drooling

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 2month

Q: Can it be taken during pregnancy?
A: Not enough studies to prove Risk – Ask your Doctor

Q: Is it safe to take for someone breastfeeding?
A: Check with your Doctor first

Precautions for GLYCOPYROLATE AND NEOSTIGMIN 0.5MG/2.5MG INJ and its Constituents

• Use this medicine (neostigmine tablets) as ordered by your doctor. Take with or without food. Take with food if it causes an upset stomach.
• Take a missed dose as soon as you think about it.
• If it is close to the time for your next dose, skip the missed dose and go back to your normal time.Do not take 2 doses at the same time or extra doses.
• Do not share your drugs with others and do not take anyone else’s drugs.
• You may need to stop using the medicine for a short time in case of a surgery.
• Use neostigmine with caution if you have epilepsy, bronchial asthma, bradycardia, recent coronary occlusion, vagotonia, hyperthyroidism, cardiac arrhythmias, peptic ulcer.
• Avoid taking large doses of neostigmine in situations where there might be an increased absorption rate from the intestinal tract.
• Use with caution when neostigmine is given along with anticholinergic drugs because of decreased GI motility.Do not drive or operate machinery as neostigmine can cause blurred vision or impaired thinking.
• Do not drink alcohol while taking neostigmine as it may worsen the side effects.
• Take precautions while taking neostigmine as over dosage of neostigmine can cause extreme muscle weakness.

• Before taking glycopyrrolate, tell your doctor or pharmacist if you are allergic to it or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
• Caution should be exercised in patients with history of pregnancy, breastfeeding, heart disease, increased level of thyroid hormone, liver or kidney impairment, enlarged prostate, diarrhea, fever, children and elderly people.
• This drug may make you dizzy or drowsy or blur your vision. Alcohol can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Limit alcoholic beverages.
• Older adults may be more sensitive to the side effects of this drug, especially drowsiness, confusion, unusual excitement, constipation, and urination problems.
• During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
• It may cause ileus (abruption of gastrointestinal motor activity) or megacolon in patients with ulcerative colitis.

Symptoms of Overdosage

NEOSTIGMINE over-dosage can result in: Constipation, Difficulty Urinating, Dry Mouth, Eyes Enlarged (dilated) Pupils
GLYCOPYRROLATE over-dosage can result in: Weakness (generalized), Eyes Enlarged (dilated) Pupils, Seizures (uncontrollable Jerking Of Limbs)

Common Side-Effects

NEOSTIGMINE : Diarrhoea, Vision Problems, Head Headache, Dizziness, Abdomen Upset Stomach, Dry Mouth, Difficulty Sleeping, Excessive Mouth Watering, Nausea, Vomit, Abdomen Stomach Cramps, Irregular Heartbeat
GLYCOPYRROLATE : Febrile Convulsions, Seizure, Skin Rash, Abdomen Pain, Chest Pain, Confusion, Dizziness, Dry Mouth, Fainting, Rapid Heart Rate (pulse), Lightheadedness, Rapid Breathing, Shortness Of Breath, Eyes Sunken Eyes, Increased Thirst, Vomit, Wheezing

Serious Side-Effects

NEOSTIGMINE : Anaphylaxis, Blood Pressure, Low, Respiratory Failure, Asthma, Flatulence, Fainting, Difficulty Breathing, Joint Pain, Frequent Urination, Body Excessive Sweating
GLYCOPYRROLATE : Body Pain, Chills, Constipation, Cough, Decreased Urination, Difficulty Urinating, Difficulty Breathing, Fever, Head Headache, Loss Of Voice, Nasal Congestion, Pain With Urination, Runny Nose, Sneezing, Throat Soreness

Disease Interactions

GLYCOPYRROLATE can interfere with: Heart Arrhythmias, Tardive Dyskinesia, Diarrhoea, Psychosis, Glaucoma, Hypertension, Fever

Technical Classification

NEOSTIGMINE is categorized as:

• CHOLINERGIC MUSCLE STIMULANTS / MISCELLANEOUS AGENTS
• MISCELLANEOUS GENITOURINARY TRACT AGENTS / GENITOURINARY TRACT AGENTS

GLYCOPYRROLATE is categorized as: ANTICHOLINERGIC BRONCHODILATORS / BRONCHODILATORS / RESPIRATORY AGENTS

Available Alternatives for GLYCOPYROLATE AND NEOSTIGMIN 0.5MG/2.5MG INJ

What are the commonly available Substitutes?

GLYCOPYROLATE AND NEOSTIGMIN 0.5MG/2.5MG INJ	INR 99 for 5 ML INJECTION	NEOSTIGMINE 2.5 MG, GLYCOPYRROLATE 0.5 MG
MYO PYROLATE INJ	INR 64.88 for 5 ML INJECTION	NEOSTIGMINE 2.5 MG, GLYCOPYRROLATE 0.5 MG
STIMIN G 0.5MG/2.5MG INJ	INR 38.07 for 5 ML INJECTION	NEOSTIGMINE 2.5 MG, GLYCOPYRROLATE 0.5 MG

What are the other drugs with similar Ingredients?

PYROTROY NEO INJ

INR 59.2 for 5 ML INJECTION

GLYCOPYRROLATE , NEOSTIGMINE