ISOLAZINE 20MG/37.5MG TAB

Overview

ISOLAZINE 20MG/37.5MG TAB is a Schedule H drug.

ISOLAZINE 20MG/37.5MG TAB is composed of: HYDRALAZINE (37.5 MG), ISOSORBIDE DINITRATE (20.0 MG)

Hydralazine is a vasodilator that works by relaxing the muscles in your blood vessels to help them dilate (widen). This lowers blood pressure and allows blood to flow more easily through your veins and arteries. Hydralazine is used to treat high blood pressure (hypertension).

Isosorbide Dinitrate is a nitrate. It works by relaxing the blood vessels which decreases the oxygen demand of the heart and reduces its workload. It thus prevents/treats attacks of angina (chest pain).

Usage

HYDRALAZINE is generally used to treat: Hypertension

ISOSORBIDE DINITRATE is generally used to treat: Angina, Unstable

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Check with your Doctor first

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 18yrs

Q: Can it be taken during pregnancy?
A: Not enough studies to prove Risk – Ask your Doctor

Q: Is it safe to take for someone breastfeeding?
A: Not Safe

Precautions for ISOLAZINE 20MG/37.5MG TAB and its Constituents

Caution should be exercised in patients with history of heart disease, kidney or liver disease, heart attack, any allergy, who are taking other medications, children, during pregnancy and breastfeeding. It may cause dizziness, do not drive a car or operate machinery while taking this medication. Avoid alcohol consumption. Monitor complete blood counts, blood pressure and antinuclear antibody titers while taking this medication.
Caution should be exercised in patients with history of anemia, dehydration, heart disease, low blood pressure, liver impairment, lupus, overactive thyroid, head injury, recent heart attack, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding. It may cause dizziness or lightheadedness, do not drive a car or operate machinery and get up slowly from bed while taking this medication. Avoid alcohol consumption.

Symptoms of Overdosage

HYDRALAZINE over-dosage can result in: Difficulty Breathing, Dizziness, Fainting, Left Arm Pain, Chest Pain, Jaws Pain, Irregular Heartbeat
ISOSORBIDE DINITRATE over-dosage can result in: Head Headache, Fever, Confusion, Dizziness, Rapid Heart Rate (pulse), Nausea, Vomit, Abdomen Pain, Bloody Or Red Colored Stools, Difficulty Breathing, Fainting, Seizures (uncontrollable Jerking Of Limbs)

Common Side-Effects

HYDRALAZINE : Head Headache, Nausea, Rapid Heart Rate (pulse), Loss Of Appetite, Loose Motion, Dizziness

Serious Side-Effects

HYDRALAZINE : Fatigue (tiredness), Dark Colored (brown) Urine, Throat Soreness, Fever, Chills

Rare Side-Effects

HYDRALAZINE : Skin Rash, Body Itching, Face Swelling, Dizziness, Difficulty Breathing
ISOSORBIDE DINITRATE : Throat Soreness, Pale Skin, Dark Colored (brown) Urine, Easy Bruising, Fatigue (tiredness), Weakness (generalized)

Disease Interactions

ISOSORBIDE DINITRATE can interfere with: Myocardial Infarction, Congestive Heart Disease, Anemia, Hypotension, Diarrhoea, Cerebrovascular Insufficeincy, Shock, Pericarditis, Aortic Valve Stenosis, Brain Tumor, Intracranial Hematoma, Benign Intracranial Hypertension, Hypertrophic Cardiomyopathy, Glaucoma

Technical Classification

HYDRALAZINE is categorized as: VASODILATORS / CARDIOVASCULAR AGENTS
ISOSORBIDE DINITRATE is categorized as: ANTIANGINAL AGENTS / CARDIOVASCULAR AGENTS

Available Alternatives for ISOLAZINE 20MG/37.5MG TAB

What are the commonly available Substitutes?

ISOLAZINE 20MG/37.5MG TAB

INR 65.5 for 10 TABLETS

HYDRALAZINE 37.5 MG, ISOSORBIDE DINITRATE 20.0 MG