LEKGAT M 200MG/500MG TAB

Overview

LEKGAT M 200MG/500MG TAB is a Schedule H antibiotic.

LEKGAT M 200MG/500MG TAB is composed of: METRONIDAZOLE (500.0 MG), GEFITINIB (200.0 MG)

Metronidazole is an antibiotic. It kills the bacteria and other microorganisms that cause infections by damaging their DNA. Metronidazole is used in the treatment of bacterial infections and parasitic infections. It is used in infections of the brain, reproductive system, gastrointestinal tract, skin, vagina, and other areas of the body.

Gefitinib is used to treat non-small cell lung cancer. Gefitinib is a cancer medication that interferes with the growth and spread of cancer cells in the body. Gefitinib belongs to a group of drugs called epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors.

Usage

METRONIDAZOLE is generally used to treat: Bacterial Infection, Brain Infection, Deep Skin Infection

GEFITINIB is generally used to treat: Lung Cancer

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 2month

Q: Can it be taken during pregnancy?
A: Studies indicate Risk – Doctor advice is must

Precautions for LEKGAT M 200MG/500MG TAB and its Constituents


Caution should be exercised in patients with history of nerve, brain, Crohn�s disease, liver impairment, seizures, heart disease, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding. It may cause dizziness, do not drive a car or operate machinery while taking this medication. Avoid alcohol consumption. Avoid long-term use of this medication; otherwise it may cause secondary infection.



  • Before using this medication, ask your doctor or pharmacist about your medical history, especially of lung disease, severe kidney disease, eye problems, stomach/intestinal ulcers, other stomach/intestinal problems, smoking, cancer that has spread to the bowels.
  • Do not take gefitinib if you are allergic to any of its ingredients.
  • Before starting gefitinib treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.).   Do not take aspirin, or products containing aspirin unless your doctor specifically permits this.
  • Do not receive any kind of immunization or vaccination without your doctor’s approval while taking gefitinib.
  • For both men and women: Do not conceive a child (get pregnant) while taking gefitinib. Barrier methods of contraception, such as condoms, are recommended. Discuss with your doctor when you may safely become pregnant or conceive a child after therapy.

Symptoms of Overdosage

METRONIDAZOLE over-dosage can result in: Nausea, Vomit, Dizziness, Loss Of Balance, Seizures (uncontrollable Jerking Of Limbs)

Common Side-Effects

METRONIDAZOLE : Skin Rash, Hives, Agitation, Back Pain, Eyes Blurred Vision, Confusion, Dizziness, Drowsiness, Eyes Pain, Fever, Head Headache, Loss Of Coordination, Nausea, Seizures (uncontrollable Jerking Of Limbs), Slurred Speech, Vomit, Black (tar) Colored Stools, Blood Or Red Colored Urine, Nasal Congestion, Runny Nose
GEFITINIB : Eyes Burning Sensation, Chest Pain, Chills, Cough, Difficulty Breathing, Eyes Dry Eyes, Shortness Of Breath

Serious Side-Effects

METRONIDAZOLE : Dark Colored (brown) Urine, Abdomen Pain, Throat Soreness, Eyes Pain, Head Headache
GEFITINIB : Abdomen Pain, Dark Colored (brown) Urine, Decreased Appetite, Fever, Nausea, Vomit

Rare Side-Effects

METRONIDAZOLE : Chest Pain, Constipation, Rapid Heart Rate (pulse)
GEFITINIB : Bloody Or Red Colored Stools, Eyes Redness, Eyes Eye Irritation, Heartburn, Abdomen Pain, Throat Soreness, Vomit

Food Interactions



Grapefruit may increase serum product levels.

Technical Classification

METRONIDAZOLE is categorized as:
  • AMEBICIDES / ANTI-INFECTIVES
  • MISCELLANEOUS ANTIBIOTICS / ANTI-INFECTIVES

GEFITINIB is categorized as: EGFR INHIBITORS / ANTINEOPLASTICS

Available Alternatives for LEKGAT M 200MG/500MG TAB

What are the commonly available Substitutes?

LEKGAT M 200MG/500MG TABINR 52 for 10 TABLETSMETRONIDAZOLE 500.0 MG, GEFITINIB 200.0 MG