LOSA RH 2.5MG/50MG/12.5MG TAB - mTatva Health-PIE

Contents

1 Overview
2 Usage
3 Frequently Asked Questions
4 How Do I Take It?
5 Precautions for LOSA RH 2.5MG/50MG/12.5MG TAB and its Constituents
6 Symptoms of Overdosage
7 Common Side-Effects
8 Serious Side-Effects
9 Rare Side-Effects
10 Disease Interactions
11 Technical Classification
12 Available Alternatives for LOSA RH 2.5MG/50MG/12.5MG TAB
- 12.1 What are the commonly available Substitutes?
- 12.2 What are the other drugs with similar Ingredients?
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Overview

LOSA RH 2.5MG/50MG/12.5MG TAB is a Schedule H drug.

LOSA RH 2.5MG/50MG/12.5MG TAB is composed of: LOSARTAN POTASSIUM (50.0 MG), HYDROCHLOROTHIAZIDE (12.5 MG), RAMIPRIL (2.5 MG)

Losartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.Losartan is used to slow long-term kidney damage in people with type 2 diabetes who also have high blood pressure.Losartan is an angiotensin receptor blocker (ARB). It works by blocking the hormone angiotensin thereby relaxing blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently.

HCTZ (hydrochlorothiazide) is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. HCTZ treats fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or kidney disorders, or edema caused by taking steroids or estrogen. This medication is also used to treat high blood pressure (hypertension).

Ramipril is an ACE inhibitor. ACE stands for angiotensin converting enzyme.Ramipril is used to treat high blood pressure (hypertension) or congestive heart failure, and to improve survival after a heart attack.It works by reducing stress on the heart and relaxing blood vessel so that blood flows more smoothly and the heart can pump blood more efficiently.

Usage

LOSARTAN POTASSIUM is generally used to treat: Hypertension, Diabetic Nephropathy
LOSARTAN POTASSIUM can address symptoms like: Shortness Of Breath, Chest Pain, Slow Or Irregular Breathing

HYDROCHLOROTHIAZIDE is generally used to treat: Edema, Hypertension

RAMIPRIL is generally used to treat: Congestive Heart Disease, Hypertension
RAMIPRIL can address symptoms like: Chest Pain, Irregular Heartbeat, Fever, Head Headache, Dizziness, Ankles Swelling, Legs Swelling, Shortness Of Breath, Difficulty Breathing, Rapid Heart Rate (pulse)

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Ask your doctor

Q: Can it be taken during pregnancy?
A: Studies indicate Risk – Doctor advice is must

How Do I Take It?

LOSA RH 2.5MG/50MG/12.5MG TAB is generally taken With Food.

Precautions for LOSA RH 2.5MG/50MG/12.5MG TAB and its Constituents

Do not use if you are pregnant.
You should not use this medication if you are allergic to losartan.
If you have diabetes, do not use losartan together with any medication that contains aliskiren.
Take losartan exactly as prescribed by your doctor. Follow all directions on your prescription label.
Your doctor may occasionally change your dose to make sure you get the best results.
Do not take this medicine in larger or smaller amounts or for longer than recommended.
Your blood pressure will need to be checked often.
It may take 3 to 6 weeks of using losartan before your blood pressure is under control.
Do not take extra medicine to make up the missed dose.
Drinking alcohol can further lower your blood pressure and may increase certain side effects of losartan.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Caution should be exercised in patients with history of diabetes, gout, asthma or kidney, liver, thyroid disease, any allergy, who are taking other medications, during pregnancy and breastfeeding. It may cause dizziness or blurred vision, do not drive a car or operate machinery while taking this medication. Avoid alcohol consumption. It may raise blood sugar level, monitor sugar level regularly while taking this medication. Monitor kidney function, blood pressure and electrolyte levels while taking this medication.

Do not use ramipril if you are pregnant.
You should not use ramipril if you have ever had angioedema.
Do not take this medicine within 36 hours before or after taking medicine that contains sacubatril.You should not use ramipril if you are allergic to it.
If you have diabetes, do not use ramipril together with any medication that contains aliskiren.
You may also need to avoid taking ramipril with aliskiren if you have kidney disease.
Take ramipril exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose.
Do not take this medicine in larger or smaller amounts or for longer than recommended.
Swallow the tablet whole.
Drink plenty of water each day while you are taking this medication
Do not take extra medicine to make up the missed dose. Avoid drinking alcohol. It can further lower your blood pressure and may increase some of the side effects of ramipril.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
Ramipril can make you feel dizzy for the first few days. Take it preferably at bedtime.

Symptoms of Overdosage

LOSARTAN POTASSIUM over-dosage can result in: Dizziness, Fainting
HYDROCHLOROTHIAZIDE over-dosage can result in: Nausea, Weakness (generalized), Dizziness, Dry Mouth, Increased Thirst
RAMIPRIL over-dosage can result in: Dizziness, Fainting

Common Side-Effects

LOSARTAN POTASSIUM : Insomnia, Heartburn, Indigestion, Fever, Runny Nose, Sneezing, Throat Soreness, Cold, Cough, Legs Pain, Head Headache, Abdomen Pain, Dizziness, Fatigue (tiredness), Difficulty Sleeping, Chills, Pale Skin, Nausea, Body Pain, Nasal Congestion, Back Pain, Belching, Body Loss Of Movement, Knees Joint Pain, Joint Pain, Eyes Pain, Abdomen Discomfort, Weight Gain
HYDROCHLOROTHIAZIDE : Diarrhoea, Abdomen Upset Stomach, Lightheadedness, Head Headache, Decreased Urination, Confusion, Irregular Heartbeat
RAMIPRIL : Acute Renal Failure, Hypotension, Head Headache, Cough, Dizziness, Weakness (generalized), Fatigue (tiredness), Arms Pain, Back Pain, Jaws Pain, Chills, Chest Discomfort, Cloudy Urine With Strong Odor, Decreased Urination, Irregular Heartbeat, Fainting, Shortness Of Breath, Nausea, Vomit, Confusion, Body Excessive Sweating

Serious Side-Effects

LOSARTAN POTASSIUM : Anxiety, Depression, Blindness, Night Terrors, Hyperkalemia, Blood Or Red Colored Urine, Anxiety, Eyes Blurred Vision, Confusion, Difficulty Breathing, Pain With Urination, Rapid Heart Rate (pulse), Irregular Heartbeat, Frequent Urge To Urinate, Lower Back Pain, Hands Tingling, Feet Tingling, Shortness Of Breath, Slurred Speech, Loss Of Voice, Eyes Change In Vision
HYDROCHLOROTHIAZIDE : Eyes Decreased Night Vision, Eyes Pain
RAMIPRIL : Angioedema, Hyperkalemia, Eyes Blurred Vision, Face Swelling, Eyes Swelling, Swollen Lips, Hoarse Voice, Difficulty Swallowing, Difficulty Breathing, Eyes Yellow Eyes

Rare Side-Effects

LOSARTAN POTASSIUM : Dry Skin, Skin Rash, Chest Pain, Arms Pain, Back Pain, Chest Discomfort, Lightheadedness, Difficulty Talking, Pounding Heart (pulse), Body Excessive Sweating, Jaws Pain, Face Swelling, Sudden Numbness Or Weakness On One Side Of Body, Legs Weakness, Ankles Joint Pain, Abdomen Bloating Or Fullness, Decreased Taste, Increased Passing Gas, Abdomen Painful Bowel Movements, Loss Of Appetite, Hair Loss, Hearing Loss, Weight Loss (unintentional), Body Discoloration
HYDROCHLOROTHIAZIDE : Body Itching, Face Swelling, Difficulty Breathing
RAMIPRIL : Acute Liver Failure, Neutropenia, Skin Rash

Disease Interactions

RAMIPRIL can interfere with: Angioedema, Acute Renal Failure, Congestive Heart Disease, Hyperkalemia, Diabetes Mellitus, Diarrhoea, Vomiting, Hyponatremia, Acute Liver Failure

Technical Classification

LOSARTAN POTASSIUM is categorized as: ANGIOTENSIN RECEPTOR BLOCKERS / CARDIOVASCULAR AGENTS
HYDROCHLOROTHIAZIDE is categorized as: THIAZIDE DIURETICS / DIURETICS / CARDIOVASCULAR AGENTS
RAMIPRIL is categorized as: ANGIOTENSIN CONVERTING ENZYME INHIBITORS / CARDIOVASCULAR AGENTS

Available Alternatives for LOSA RH 2.5MG/50MG/12.5MG TAB

What are the commonly available Substitutes?

LORAM-H 2.5 TAB	INR 102.5 for 10 TABLETS	LOSARTAN POTASSIUM 50.0 MG, HYDROCHLOROTHIAZIDE 12.5 MG, RAMIPRIL 2.5 MG
LOSA RH 2.5MG/50MG/12.5MG TAB	INR 67.73 for 10 TABLETS	LOSARTAN POTASSIUM 50.0 MG, HYDROCHLOROTHIAZIDE 12.5 MG, RAMIPRIL 2.5 MG
LOSANORM HR TAB	INR 58.22 for 10 TABLETS	LOSARTAN POTASSIUM 50.0 MG, HYDROCHLOROTHIAZIDE 12.5 MG, RAMIPRIL 2.5 MG
LR H TAB	INR 69.95 for 10 TABLETS	LOSARTAN POTASSIUM 50.0 MG, HYDROCHLOROTHIAZIDE 12.5 MG, RAMIPRIL 2.5 MG
SARTACE H 2.5MG/50MG/12.5MG TAB	INR 66.58 for 10 TABLETS	LOSARTAN POTASSIUM 50.0 MG, HYDROCHLOROTHIAZIDE 12.5 MG, RAMIPRIL 2.5 MG

What are the other drugs with similar Ingredients?

COVARACE D 2.5MG/25MG/12.5MG TAB	INR 78.75 for 10 TABLETS	LOSARTAN POTASSIUM 25.0 MG, HYDROCHLOROTHIAZIDE 12.5 MG, RAMIPRIL 2.5 MG
LORAM-H 5 TAB	INR 117 for 10 TABLETS	LOSARTAN POTASSIUM 50.0 MG, HYDROCHLOROTHIAZIDE 12.5 MG, RAMIPRIL 5.0 MG