LUPISETRON PLUS 4MG/500MG TAB

Overview

LUPISETRON PLUS 4MG/500MG TAB is a Schedule H drug.

LUPISETRON PLUS 4MG/500MG TAB is composed of: PARACETAMOL (500.0 MG), ONDANSETRON HYDROCHLORIDE (4.0 MG)

Paracetamol is a pain reliever and a fever reducer. The exact mechanism of action of is not known. Paracetamol is used to treat many conditions such as a headache, muscle aches, arthritis, backache, toothaches, colds, and fevers. It relieves pain in mild arthritis but has no effect on the underlying inflammation and swelling of the joint.

Ondansetron is a 5-HT3 receptor antagonist, prescribed for nausea and vomiting caused by cancer chemotherapy, radiation therapy and surgery. It blocks serotonin receptors in the vomiting center and on nerves supplying the digestive system. This medication comes in several oral forms tablets, orally disintegrating (dissolving) tablets, an oral soluble film, and solution (liquid). Ondansetron is also available in an injectable form to be given directly into a vein (IV) by a healthcare professional.

Usage

PARACETAMOL is generally used to treat: Arthritis
PARACETAMOL can address symptoms like: Head Headache, Back Pain, Cold, Fever

ONDANSETRON HYDROCHLORIDE is generally used to treat: Cancer
ONDANSETRON HYDROCHLORIDE can address symptoms like: Nausea, Vomit

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Check with your Doctor first

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 1month

Q: Can it be taken during pregnancy?
A: Considered as Generally Safe – not enough studies to prove risk

Q: Is it safe to take for someone breastfeeding?
A: Not Safe

Precautions for LUPISETRON PLUS 4MG/500MG TAB and its Constituents

Caution should be exercised in patients with history of asthma, bleeding problems, growths in the nose, heart, kidney or liver disease, liver inflammation, high blood pressure, chickenpox, anxiety, trouble in sleeping, ulcers, stomach problems, stroke, Kawasaki syndrome, any allergy, who are taking other medications, during pregnancy and breastfeeding. Avoid alcohol consumption. It should not be used in children with infections such as flu, chickenpox or viral infections. Avoid large amount of caffeinated beverages while taking this medication. It may reduce platelet counts; avoid injury or bruising.

• Before taking ondansetron, tell your doctor or pharmacist if you are allergic to it or to other serotonin blockers or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
• Before using this medication, tell your doctor or pharmacist your medical history, especially of irregular heartbeat, liver disease, stomach/intestinal problems.
• Ondansetron may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.
• Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting.
• This drug may make you dizzy or drowsy. Alcohol or marijuana can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages.
• This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.
• It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.

Symptoms of Overdosage

PARACETAMOL over-dosage can result in: Loss Of Appetite, Nausea, Vomit, Abdomen Pain, Weakness (generalized), Upper Abdomen Pain, Dark Colored (brown) Urine, Eyes Yellow Eyes

Common Side-Effects

ONDANSETRON HYDROCHLORIDE : Confusion, Dizziness, Fever, Head Headache, Weakness (generalized), Decreased Urination, Pain With Urination

Serious Side-Effects

ONDANSETRON HYDROCHLORIDE : Irregular Heartbeat, Difficulty Breathing, Shortness Of Breath, Rapid Heart Rate (pulse)

Rare Side-Effects

PARACETAMOL : Skin Rash, Dizziness, Difficulty Breathing, Face Swelling, Body Itching
ONDANSETRON HYDROCHLORIDE : Skin Rash, Hives, Arms Pain, Jaws Pain, Convulsions, Cough, Difficulty Swallowing, Dry Mouth, Increased Thirst, Mood Swings, Vomit, Nausea, Noisy Breathing, Body Excessive Sweating, Wheezing

Disease Interactions

ONDANSETRON HYDROCHLORIDE can interfere with: Hypokalemia, Congestive Heart Disease, Heart Arrhythmias, Acute Liver Failure

Technical Classification

PARACETAMOL is categorized as: MISCELLANEOUS ANALGESICS / ANALGESICS / CENTRAL NERVOUS SYSTEM AGENTS
ONDANSETRON HYDROCHLORIDE is categorized as: 5HT3 RECEPTOR ANTAGONISTS / ANTIEMETIC/ANTIVERTIGO AGENTS / CENTRAL NERVOUS SYSTEM AGENTS

Available Alternatives for LUPISETRON PLUS 4MG/500MG TAB

What are the commonly available Substitutes?

LUPISETRON PLUS 4MG/500MG TAB	INR 12.83 for 10 TABLETS	PARACETAMOL 500.0 MG, ONDANSETRON HYDROCHLORIDE 4.0 MG
SATRON PLUS 4MG/500MG TAB	INR 47.5 for 10 TABLETS	PARACETAMOL 500.0 MG, ONDANSETRON HYDROCHLORIDE 4.0 MG

What are the other drugs with similar Ingredients?

EMVON PLUS DPS	INR 16 for 30 ML DROP	PARACETAMOL , ONDANSETRON HYDROCHLORIDE
MYSET PLUS TAB	INR 35 for 10 TABLETS	PARACETAMOL , ONDANSETRON HYDROCHLORIDE
SATRON PLUS 2MG/125MG SUSP	INR 35 for 30 ML SUSPENSION	PARACETAMOL 125.0 MG, ONDANSETRON HYDROCHLORIDE 2.0 MG