MALARCE TAB

Overview

MALARCE TAB is a Schedule H drug.

MALARCE TAB is composed of: PYRIMETHAMINE ( ), SULFAMETHOXAZOLE ( )

Pyrimethamine is an antiparasite medicine that helps prevent parasites from growing and reproducing in the body.Pyrimethamine is used in adults and children to treat or prevent certain types of malaria. It is usually taken with a sulfonamide. Discontinue if rash occurs.It works by increasing the levels of haeme in the blood, a substance toxic to the malarial parasite. This kills the parasite and stops the infection from spreading.


  Sulfamethoxazole is a sulfa agent, eliminates bacteria that cause infections, especially urinary tract infections.

Usage

PYRIMETHAMINE is generally used to treat: Malaria, Toxoplasmosis
PYRIMETHAMINE can address symptoms like: Fever, Head Headache

SULFAMETHOXAZOLE is generally used to treat: Urinary Tract Infection

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 2yrs

Q: Can it be taken during pregnancy?
A: Not enough studies to prove Risk – Ask your Doctor

Q: Is it safe to take for someone breastfeeding?
A: Not Safe

How Do I Take It?

MALARCE TAB is generally taken Before Food.

Precautions for MALARCE TAB and its Constituents

• You should not use pyrimethamine if you are allergic to it.
• Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take this medicine in larger or smaller amounts or for longer than recommended.
• Follow your doctor’s dosing instructions very carefully.
• Take with food if pyrimethamine upsets your stomach or affects your appetite.
• Pyrimethamine is often given in combination with other medications.
• Use all medications as directed by your doctor. While using pyrimethamine, you may need frequent blood tests.
• Do not take extra medicine to make up the missed dose. Take with plenty of water to prevent crystal or stone formation in the urinary tract.
• Avoid excessive exposure to sun.
• Pyrimethamine when given with sulphonamide, it should be given with folic acid (vitamin) supplement.
• Do not take pyrimethamine if you have megaloblastic anemia due to folate deficiency.

Caution should be exercised in patients with history of kidney or liver impairment, history of allergy or asthma, AIDS, G6PD deficiency, elderly, and children. Avoid excess dosage.

Symptoms of Overdosage

PYRIMETHAMINE over-dosage can result in: Abdomen Pain, Cough, Bloody Or Red Colored Vomit, Slow Or Irregular Breathing, Hyperactive Behavior, Seizures (uncontrollable Jerking Of Limbs), Difficult To Wake From Sleep

Common Side-Effects

PYRIMETHAMINE : Diarrhoea, Anorexia Nervosa, Anemia, Vomit, Loss Of Appetite, Black (tar) Colored Stools, Blood Or Red Colored Urine, Bloody Or Red Colored Stools, Cough, Fever, Chills, Lower Back Pain, Pain With Urination, Difficulty Urinating, Dizziness, Head Headache
SULFAMETHOXAZOLE : Anorexia Nervosa, Low Blood Sugar, Serum Sickness, Kernicterus, Diarrhoea, Nausea, Vomit

Serious Side-Effects

PYRIMETHAMINE : Breathlessness, Pale Skin, Fatigue (tiredness), Throat Soreness, Rapid Breathing, Rapid Heart Rate (pulse), Easy Bleeding, Swollen Tongue

Rare Side-Effects

PYRIMETHAMINE : Skin Rash, Hives, Mouth Ulcer, Chest Pain, Mouth Soreness, Difficulty Swallowing, Fainting, Lightheadedness, Slow Or Irregular Breathing, Pounding Heart (pulse), Eyes Swelling, Rapid Breathing, Eyes Eye Irritation, Eyes Redness, Shortness Of Breath, Wheezing

Disease Interactions

SULFAMETHOXAZOLE can interfere with: Bone Marrow Suppression, G6pd Deficiency, Asthma, Human Immunodeficiency Virus, Allergy, Acute Liver Failure, Porphyria, Acute Renal Failure, Colitis, Gastroenteritis, Diarrhoea, Vomiting, Urinary Retention

Technical Classification

PYRIMETHAMINE is categorized as: MISCELLANEOUS ANTIMALARIALS / ANTIMALARIAL AGENTS / ANTI-INFECTIVES
SULFAMETHOXAZOLE is categorized as: SULFONAMIDES / ANTI-INFECTIVES

Available Alternatives for MALARCE TAB

What are the commonly available Substitutes?

MALARCE TAB

INR 20 for 2 TABLETS

PYRIMETHAMINE , SULFAMETHOXAZOLE

What are the other drugs with similar Ingredients?

G KELFIN 25MG/500MG TAB	INR 7 for 2 TABLETS	SULFAMETHOXAZOLE 500.0 MG, PYRIMETHAMINE 25.0 MG
LARI 12.5MG/250MG SUSP	INR 55 for 10 ML SUSPENSION	SULFAMETHOXAZOLE 250.0 MG, PYRIMETHAMINE 12.5 MG
LARI 25MG/500MG TAB	INR 52 for 3 TABLETS	SULFAMETHOXAZOLE 500.0 MG, PYRIMETHAMINE 25.0 MG
MALIN 12.5MG/250MG SYP	INR 8.88 for 10 ML SYRUP	SULFAMETHOXAZOLE 250.0 MG, PYRIMETHAMINE 12.5 MG
MALIN 25MG/500MG TAB	INR 19.93 for 2 TABLETS	SULFAMETHOXAZOLE 500.0 MG, PYRIMETHAMINE 25.0 MG
MELAR 25MG/500MG TAB	INR 8.73 for 2 TABLETS	SULFAMETHOXAZOLE 500.0 MG, PYRIMETHAMINE 25.0 MG