Contents
- 1 Overview
- 2 Usage
- 3 Frequently Asked Questions
- 4 Precautions for MEXATE COMBIPACK 25MG INJ and its Constituents
- 5 Common Side-Effects
- 6 Serious Side-Effects
- 7 Food Interactions
- 8 Disease Interactions
- 9 Technical Classification
- 10 Available Alternatives for MEXATE COMBIPACK 25MG INJ
- 11 Share this:
- 12 Like this:
- 13 Related Articles
Overview
MEXATE COMBIPACK 25MG INJ is a Schedule H drug.MEXATE COMBIPACK 25MG INJ is composed of: METHOTREXATE (25.0 MG)
Methotrexate decreases the activity of the immune system and slows cancer cell growth. Reserved for conditions that cannot be treated with other medications.Methotrexate is used in the treatment of rheumatoid arthritis and psoriasis.Methotrexate is an immunosuppressant. In rheumatoid arthritis, it works by decreasing the activity of body’s immune system. This decreases swelling, reduces pain and stiffness, and improves function. In psoriasis, it works by slowing down the rapid growth of skin cells.
Usage
METHOTREXATE is generally used to treat: Rheumatoid Arthritis, Psoriasis, Head Cancer, Neck Cancer, Breast Cancer, Skin Cancer, Lung Cancer, Arthritis, JuvenileMETHOTREXATE can address symptoms like: Joint Pain, Back Pain, Fatigue (tiredness), Redness, Spinning Sensation, Hands Swelling, Dry Mouth, Pale Skin
Frequently Asked Questions
Q: Is it safe on my liver?A: Not Safe
Q: Is it safe on my kidney?
A: Not Safe
Q: Can I take it with alcohol?
A: Not Safe
Q: Is it safe for children?
A: Not Advised for age < 3yrs
Q: Can it be taken during pregnancy?
A: Dangerous – Studies indicate Human-Fetal Risk
Precautions for MEXATE COMBIPACK 25MG INJ and its Constituents
- Methotrexate is usually not taken every day.
- You must use the correct dose for your condition.
- Do not use methotrexate to treat psoriasis or rheumatoid arthritis if you have low blood cell counts, a bone marrow disorder, liver disease (especially if caused by alcoholism), or if you are pregnant or breast-feeding.
- You should not use methotrexate if you are allergic to it.
- Do not give this medicine to a child without the advice of a doctor.Take methotrexate exactly as it was prescribed for you Follow all directions on your prescription label and read all medication guides or instruction sheets.
- Methotrexate is sometimes taken once or twice per week and not every day.
- You must use the correct dose. Some people have died after taking methotrexate every day by accident.
- Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).
- Your blood will need to be tested often, If you need to be sedated for dental work, tell your dentist you currently use this medicine.
- Do not receive a "live" vaccine while using methotrexate, or you could develop a serious infection.
- This medicine can pass into body fluids (urine, feces, vomit). Caregivers should wear rubber gloves while cleaning up a patient’s body fluids, handling contaminated trash or laundry or changing diapers.
- Wash hands before and after removing gloves.
- Wash soiled clothing and linens separately from other laundry.Avoid exposure to sunlight or artificial UV rays, especially if you are being treated for psoriasis. Methotrexate can make your skin more sensitive to sunlight and your psoriasis may worsen.
- Always take folic acid as advised by your doctor. This will help lessen the side effects of Methotrexate.
Common Side-Effects
METHOTREXATE : Acne, Skin Rash, Itchy Skin, Diarrhoea, Dyspepsia, Stomatitis, Fever, Chills, Fatigue (tiredness), Mouth Soreness, Nausea, Abdomen Upset Stomach, Dizziness, Abdomen Pain, Back Pain, Eyes Blurred Vision, Confusion, Cough, Dark Colored (brown) Urine, Drowsiness, Head Headache, Pain With Urination, Lower Back Pain, Shortness Of Breath, Eyes Yellow Eyes, Easy Bruising, Vomit, Pale Skin, Loss Of AppetiteSerious Side-Effects
METHOTREXATE : Anemia, Acute Liver Failure, Acute Kidney Failure, Black (tar) Colored Stools, Blood Or Red Colored Urine, Bloody Or Red Colored Stools, Bloody Or Red Colored Vomit, Joint Pain, Feet Swelling, Hair Loss, Decreased Urination, Chest Discomfort, Weight Loss (unintentional), Face Swelling, Swollen Lips, Eyes Swelling, Swollen Tongue, Arms SwellingFood Interactions
If you are receiving methotrexate for arthritis, you may want to limit your intake of caffeine-containing foods and products.
Disease Interactions
METHOTREXATE can interfere with: Fungal Infection, Protozoal Infection, Viral Inection, Bacterial Infection, Acute Liver Failure, Alcoholism, Bone Marrow Suppression, Anemia, Acute Renal Failure, Pleural Effusion, Peptic Ulcer, Diarrhoea, Inflammatory Bowel DiseaseTechnical Classification
METHOTREXATE is categorized as:- ANTIMETABOLITES / ANTINEOPLASTICS
- ANTIPSORIATICS / MISCELLANEOUS AGENTS
- ANTIRHEUMATICS / MISCELLANEOUS AGENTS
- OTHER IMMUNOSUPPRESSANTS / IMMUNOSUPPRESSIVE AGENTS / IMMUNOLOGIC AGENTS
Available Alternatives for MEXATE COMBIPACK 25MG INJ
What are the commonly available Substitutes?
FOLITRAX 25MG INJ | INR 45.15 for 1 ML INJECTION | METHOTREXATE 25.0 MG |
FOLITRAX 25MG TAB | INR 159.5 for 4 TABLETS | METHOTREXATE 25.0 MG |
FOLITRAX AMP 25MG X 1ML | INR 105 for 1 ML INJECTION | METHOTREXATE 25 MG |
MEXATE COMBIPACK 25MG INJ | INR 55 for 1 INJECTION | METHOTREXATE 25.0 MG |
What are the other drugs with similar Ingredients?
FOLITRAX 10 MGTAB | INR 114.19 for 10 TABLETS | METHOTREXATE 10 MG |
FOLITRAX 10MG TAB | INR 114.05 for 10 TABLETS | METHOTREXATE 10.0 MG |
FOLITRAX 15MG INJ | INR 42 for 1 ML INJECTION | METHOTREXATE 15.0 MG |
FOLITRAX 15MG TAB | INR 275 for 10 TABLETS | METHOTREXATE 15 MG |
FOLITRAX 2.5MG TAB | INR 45 for 10 TABLETS | METHOTREXATE 2.5 MG |
FOLITRAX 20MG INJ | INR 64.75 for 1 ML INJECTION | METHOTREXATE 20.0 MG |
FOLITRAX 20MG TAB | INR 130 for 4 TABLETS | METHOTREXATE 20 MG |
FOLITRAX 50MG INJ | INR 90.3 for 2 ML INJECTION | METHOTREXATE 50.0 MG |
FOLITRAX 5MG TAB | INR 78.69 for 10 TABLETS | METHOTREXATE 5 MG |
FOLITRAX 7.5MG INJ | INR 26.4 for 1 ML INJECTION | METHOTREXATE 7.5 MG |
FOLITRAX 7.5MG TAB | INR 109.01 for 10 TABLETS | METHOTREXATE 7.5 MG |
FOLITRAX AMP 15MG X1ML | INR 44 for 1 ML INJECTION | METHOTREXATE 15 MG |
FOLITRAX AMP 7.5MG X 1ML | INR 22 for 1 ML INJECTION | METHOTREXATE 7.5 MG |
FOLITRAX INJ | INR 71.22 for 1 ML INJECTION | METHOTREXATE 20 MG |
HITREX 15MG INJ | INR 51 for 1 ML INJECTION | METHOTREXATE 15.0 MG |
HITREX 50MG INJ | INR 50.48 for 2 ML INJECTION | METHOTREXATE 50.0 MG |
IMUTREX 10MG TAB | INR 45.4 for 4 TABLETS | METHOTREXATE 10.0 MG |
IMUTREX 15MG INJ | INR 51 for 2 ML INJECTION | METHOTREXATE 15.0 MG |
IMUTREX 2.5MG TAB | INR 46.37 for 10 TABLETS | METHOTREXATE 2.5 MG |
IMUTREX TAB 7.5MG | INR 108.36 for 10 TABLETS | METHOTREXATE 7.5 MG |
MEDITREX 10MG TAB | INR 161.68 for 10 TABLETS | METHOTREXATE 10.0 MG |
MEDITREX 15MG TAB | INR 185.62 for 10 TABLETS | METHOTREXATE 15.0 MG |
MEDITREX 5MG TAB | INR 79 for 10 TABLETS | METHOTREXATE 5.0 MG |
MEDITREX 7.5MG TAB | INR 130.52 for 10 TABLETS | METHOTREXATE 7.5 MG |
MEREX 1000MG INJ | INR 750 for 10 ML INJECTION | METHOTREXATE 1000.0 MG |
MEREX 500MG INJ | INR 500 for 5 ML INJECTION | METHOTREXATE 500.0 MG |
METH 2.5MG TAB | INR 50.48 for 10 TABLETS | METHOTREXATE 2.5 MG |
METHOCEL 1000MG INJ | INR 904.76 for 10 ML INJECTION | METHOTREXATE 1000.0 MG |
METHOCEL 15MG INJ | INR 36.3 for 3 ML INJECTION | METHOTREXATE 15.0 MG |
METHOCEL 2.5MG TAB | INR 33.33 for 10 TABLETS | METHOTREXATE 2.5 MG |
METHOCEL 500MG INJ | INR 580.95 for 5 ML INJECTION | METHOTREXATE 500.0 MG |
METHOCEL 50MG INJ | INR 65 for 2 ML INJECTION | METHOTREXATE 50.0 MG |
METHOCIP 50MG INJ | INR 48.75 for 2 ML INJECTION | METHOTREXATE 50.0 MG |
METHOCIP 50MG TAB | INR 15.62 for 10 TABLETS | METHOTREXATE 50.0 MG |
METHOFAST 15MG INJ | INR 52.93 for 3 ML INJECTION | METHOTREXATE 15.0 MG |
METHOFAST 50MG INJ | INR 59 for 2 ML INJECTION | METHOTREXATE 50.0 MG |
METHOREX 2.5MG TAB | INR 16.5 for 10 TABLETS | METHOTREXATE 2.5 MG |
METHOTREXATE | METHOTREXATE | |
MEXATE 10MG TAB | INR 45.4 for 4 TABLETS | METHOTREXATE 10 MG |
MEXATE 15MG TAB | INR 116 for 4 TABLETS | METHOTREXATE 15 MG |
MEXATE 2.5MG TAB | INR 17.89 for 4 TABLETS | METHOTREXATE 2.5 MG |
MEXATE 5MG TAB | INR 31.29 for 4 TABLETS | METHOTREXATE 5 MG |
MEXATE 7.5MG TAB | INR 43.34 for 4 TABLETS | METHOTREXATE 7.5 MG |
MEXT 10MG TAB | INR 150 for 10 TABLETS | METHOTREXATE 10 MG |
MEXT 15MG TAB | INR 227.75 for 10 TABLETS | METHOTREXATE 15.0 MG |
MEXT 2.5MG TAB | INR 49.65 for 10 TABLETS | METHOTREXATE 2.5 MG |
MEXT 5MG TAB | INR 78.22 for 10 TABLETS | METHOTREXATE 5.0 MG |
MEXT 7.5MG TAB | INR 108.36 for 10 TABLETS | METHOTREXATE 7.5 MG |
MEXT F 7.5MG/1MG TAB | INR 60 for 28 TABLETS | METHOTREXATE 7.5 MG, FOLIC ACID 1.0 MG |
NEOTREXATE 2.5MG TAB | INR 44.73 for 10 TABLETS | METHOTREXATE 2.5 MG |
NEOTREXATE INJ | INR 50.76 for 2 ML INJECTION | METHOTREXATE 50.0 MG |
NEOTREXATE TAB | INR 57.85 for 10 TABLETS | METHOTREXATE 2.5 MG |
ONCOTREX 10MG TAB | INR 161 for 10 TABLETS | METHOTREXATE 10 MG |
ONCOTREX 2.5MG TAB | INR 44.73 for 10 TABLETS | METHOTREXATE 2.5 MG |
ONCOTREX 50MG INJ | INR 354.5 for 1 ML INJECTION | METHOTREXATE 50.0 MG |
ONCOTREX 5MG TAB | INR 78.22 for 10 TABLETS | METHOTREXATE 5.0 MG |
ONCOTREX 7.5MG TAB | INR 114 for 10 TABLETS | METHOTREXATE 7.5 MG |
PSORIAX 5MG TAB | INR 79 for 10 TABLETS | METHOTREXATE 5.0 MG |
REMTREX 15MG INJ | INR 65 for 3 ML INJECTION | METHOTREXATE 15.0 MG |
REMTREX 2.5MG TAB | INR 22.5 for 10 TABLETS | METHOTREXATE 2.5 MG |
REMTREX 50MG INJ | INR 73.27 for 2 ML INJECTION | METHOTREXATE 50.0 MG |
REMTREX INJ | INR 713.42 for 1 INJECTION | METHOTREXATE |
RHUTRAX 15MG TAB | INR 249 for 10 TABLETS | METHOTREXATE 15.0 MG |
RHUTRAX 7.5MG TAB | INR 126 for 10 TABLETS | METHOTREXATE 7.5 MG |
RHUTREX 10MG TAB | INR 156 for 10 TABLETS | METHOTREXATE 10.0 MG |
TREX 2.5MG TAB | INR 36.25 for 10 TABLETS | METHOTREXATE 2.5 MG |
TREXOPAR 15MG INJ | INR 55 for 3 ML INJECTION | METHOTREXATE 15.0 MG |
TREXOPAR 50MG INJ | INR 115 for 3 ML INJECTION | METHOTREXATE 50.0 MG |
TRUXOFOL 7.5MG/1MG TAB | INR 50 for 28 TABLETS | METHOTREXATE 7.5 MG, FOLIC ACID 1.0 MG |
UNITREXATE 15MG INJ | INR 48 for 3 ML INJECTION | METHOTREXATE 15.0 MG |
UNITREXATE 50MG INJ | INR 60.5 for 2 ML INJECTION | METHOTREXATE 50.0 MG |
UNITREXATE INJ | INR 47.4 for 3 ML INJECTION | METHOTREXATE 5 MG/ML |
VIBZI 5MG TAB | INR 67 for 10 TABLETS | METHOTREXATE 5.0 MG |
ZEXATE 5MG INJ | INR 50 for 3 ML INJECTION | METHOTREXATE 5 MG |