ODIVIR 300MG/400MG/600MG KIT

Overview

ODIVIR 300MG/400MG/600MG KIT is a Schedule H drug.

ODIVIR 300MG/400MG/600MG KIT is composed of: EFAVIRENZ (600.0 MG), DIDANOSINE (400.0 MG), LAMIVUDINE (300.0 MG)

Efavirenz is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body. Efavirenz is used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). Efavirenz is for adults and children who are at least 3 months old and weigh at least 8 pounds. Efavirenz is not a cure for HIV or AIDS.

Didanosine is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body.Didanosine is used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). Didanosine is not a cure for HIV or AIDS. Didanosine prevents the multiplication of HIV virus in human cells. Thus stops the HIV virus from producing new viruses. Didanosine belongs to a class of drugs called nucleoside analogues which work by decreasing the amount of HIV in the blood.
Lamivudine is an antiviral medication. It prevents the multiplication of the virus in human cells. This stops the virus from producing new viruses and clears up your infection. Lamivudine is used in the treatment of HIV infection and chronic hepatitis B virus (HBV) infection.

Usage

EFAVIRENZ is generally used to treat: AIDS

DIDANOSINE is generally used to treat: Human Immunodeficiency Virus
DIDANOSINE can address symptoms like: Fever, Head Headache, Throat Soreness, Abdomen Upset Stomach, Loose Motion, Vomit

LAMIVUDINE is generally used to treat: Hepatitis B, AIDS

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Check with your Doctor first

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 1month

Q: Can it be taken during pregnancy?
A: Studies indicate Risk – Doctor advice is must

How Do I Take It?

ODIVIR 300MG/400MG/600MG KIT is generally taken Before Food.

Precautions for ODIVIR 300MG/400MG/600MG KIT and its Constituents


Efavirenz must be given in combination with other antiviral medications and it should not be used alone. Your disease may become resistant to efavirenz if you do not take it in combination with other HIV medicines your doctor has prescribed. Take efavirenz on an empty stomach at bedtime. To make swallowing easier, you may open an efavirenz capsule and sprinkle the medicine into a spoonful of applesauce, yogurt, or grape jelly. You may also mix the medicine with infant formula if you are giving the medicine to a baby. Swallow the mixture right away. Do not save it for later use. After taking efavirenz using the sprinkle method, do not eat for the next 2 hours. Efavirenz mixed with infant formula should be given to the baby right away. But do not feed the baby any more formula for at least 2 hours afterward. Efavirenz comes with instructions for mixing the capsule contents with soft food or infant formula. Follow these directions carefully. Do not crush, chew, or break an efavirenz tablet. Swallow it whole with liquid. Drinking alcohol can increase certain side effects of efavirenz. Taking this medication will not prevent you from passing HIV to other people. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.
  • Take precautions while taking didanosine as it may cause conditions such as peripheral neuropathy (numbness, tingling and pain in arms and legs), changes in eye, pancreatitis (inflammation of the pancreas), changes in body fat distribution, osteonecrosis (death of bone tissue) and reoccurrence of symptoms from previous infections (Immune Reactivation Syndrome) or opportunistic infections (infections due to weakened immune system).
  •  Seek for immediate medical attention if you develop a condition called as lactic acidosis (increased levels of lactic acid in blood), which can turn fatal if not treated; or if you observe any symptoms such as nausea, vomiting and stomach pain.
  • Inform your doctor if you are suffering from or have a history of pancreatitis (inflammation of the pancreas), kidney or liver diseases (hepatitis B or C infections)Tell your doctor if you are or are planning to become pregnant. Didanosine if consumed in combination with stavudine during pregnancy may increase the chance of lactic acidosis.
  • Patients who are taking didanosine along with ganciclovir, valganciclovir are more prone to side effects and hence require close supervision.
  • You should not use didanosine if you are allergic to it. Do not take didanosine together with allopurinol, ribavirin, or stavudine.
  • Tell your doctor if you have ever had:
  • Liver disease or pancreatitis (didanosine can cause severe or life-threatening effects on your liver or pancreas);
  • kidney disease (or if you are on dialysis);
  • numbness or tingling in your hands or feet, including Raynaud’s syndrome; or
  • if you drink large amounts of alcohol.
  • Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.Take didanosine on an empty stomach, at least 30 minutes before or 2 hours after a meal. Do not take with food.

Caution should be exercised in patients with history of hepatitis B, kidney disease, pancreas disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.  It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication. Avoid alcohol consumption. It should not be used in children less than 2 years old. It may affect blood sugar level; monitor sugar level regularly while taking this medication. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.


Symptoms of Overdosage

EFAVIRENZ over-dosage can result in: Difficulty Breathing
DIDANOSINE over-dosage can result in: Difficulty Breathing
LAMIVUDINE over-dosage can result in: Difficulty Breathing

Common Side-Effects

EFAVIRENZ : Depression, Skin Rash, Body Itching, Blood Or Red Colored Urine, Pain With Urination, Lower Back Pain
DIDANOSINE : Vomiting, Stomach Pain, Diarrhoea, Pancreatitis, Headache, Pruritus, Neutropenia, Nausea, Abdomen Pain, Vomit, Hands Pain, Feet Pain, Hands Numbness
LAMIVUDINE : Nausea, Vomit, Loose Motion, Dizziness, Head Headache, Fatigue (tiredness)

Serious Side-Effects

DIDANOSINE : Anemia, Thrombocytopenia, Restless Or Irritability, Difficulty Sleeping, Vomit
LAMIVUDINE : Mood Swings, Nausea, Vomit, Abdomen Pain, Dark Colored (brown) Urine, Eyes Yellow Eyes

Rare Side-Effects

EFAVIRENZ : Hives, Abdomen Pain, Confusion, Seizures (uncontrollable Jerking Of Limbs), Cough, Dark Colored (brown) Urine, Fainting, Fever, Chills, Head Headache, Loss Of Appetite, Nausea, Vomit
DIDANOSINE : Seizure, Skin Rash, Itchy Skin, Anxiety, Hives, Chest Pain, Night Terrors, Constipation, Indigestion, Depression, Chills, Fever, Throat Soreness, Body Discoloration, Eyes Discoloration, Feet Swelling, Weakness (generalized), Head Headache
LAMIVUDINE : Rapid Breathing, Drowsiness, Hands Numbness

Food Interactions



  • Food decreases the levels of didanosine in your body. Take didanosine on an empty stomach at least 30 minutes before or 2 hours after a meal.
  • The reverse transcriptase inhibitors, didanosine (ddI), zalcitabine (ddC), stavudine (d4T) and lamivudine (3TC), may cause pancreatitis.
  • Avoid sodium rich food supplements.

Disease Interactions

LAMIVUDINE can interfere with: Hyperlipidemia, Pancreatitis, Alcoholism, Acute Renal Failure

Technical Classification

EFAVIRENZ is categorized as: NNRTIS / ANTIVIRAL AGENTS / ANTI-INFECTIVES
DIDANOSINE is categorized as: NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS (NRTIS) / ANTIVIRAL AGENTS / ANTI-INFECTIVES
LAMIVUDINE is categorized as: NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS (NRTIS) / ANTIVIRAL AGENTS / ANTI-INFECTIVES

Available Alternatives for ODIVIR 300MG/400MG/600MG KIT

What are the commonly available Substitutes?

ODIVIR 300MG/400MG/600MG KITINR 125.19 for 3 TABLETSEFAVIRENZ 600.0 MG, DIDANOSINE 400.0 MG, LAMIVUDINE 300.0 MG

What are the other drugs with similar Ingredients?

ODIVIR 300MG/250MG/600MG KITINR 107 for 3 TABLETSEFAVIRENZ 600.0 MG, LAMIVUDINE 300.0 MG, DIDANOSINE 250.0 MG