PEALE GEL

Overview

PEALE GEL is a Schedule H drug.

PEALE GEL is composed of: METHYL SALICYLATE (10.0 %W/W), MENTHOL (5.0 %W/W), ACECLOFENAC (1.5 %W/W), CAPSAICIN (0.01 %W/W)



Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) with analgesic properties. Aceclofenac potently inhibits the cyclo-oxygenase enzyme (COX) that is involved in the synthesis of prostaglandins, which are inflammatory mediators that cause pain, swelling, inflammation, and fever.  It is orally administered for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.

Capsaicin is the active ingredient in chili peppers that makes them hot. Capsaicin is used in medicated creams and lotions to relieve muscle or joint pain.Capsaicin used on the body causes a sensation of heat that activates certain nerve cells. With regular use of capsaicin, this heating effect reduces the amount of substance P, a chemical that acts as a pain messenger in the body.Capsaicin topical is used for temporary relief of muscle or joint pain caused by strains, sprains, arthritis, bruising, or backaches. Capsaicin topical is also used to treat nerve pain (neuralgia) in people who have had herpes zoster, or "shingles." Capsaicin is the stuff in chili peppers that makes your mouth feel hot. But it’s also got a medical purpose. It’s a key ingredient in creams and patches that can give you relief from pain.

Usage

ACECLOFENAC is generally used to treat: Osteoarthritis, Rheumatoid Arthritis, Ankylosing Spondylitis

CAPSAICIN is generally used to treat: Psoriasis, Rheumatoid Arthritis, Osteoarthritis, Fibromyalgia, Migraine, Neuralgia, Postherpetic, Muscle Strain
CAPSAICIN can address symptoms like: Head Headache, Skin Irritation

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 18yrs

Q: Can it be taken during pregnancy?
A: Not enough studies to prove Risk – Ask your Doctor

Q: Is it safe to take for someone breastfeeding?
A: Not Safe

How Do I Take It?

PEALE GEL is generally taken With Food.

Precautions for PEALE GEL and its Constituents

• if the stools in black or blood consult your doctor.
• not fully safe to take while pregnant and breastfeeding.
• swallow the tablet whole with aglass of water do not crush or chew the tablets.

• Do not use this medicine if you are allergic to chili peppers, or if you have ever had an allergic reaction to capsaicin topical.
• Capsaicin can cause a burning sensation wherever it is applied. If you have significant discomfort or skin redness, wash the treated skin area with soap and cool water.
• Get medical attention right away if you have severe burning, pain, swelling, or blistering of the skin where you applied this medication.
• Ask a doctor or pharmacist about using capsaicin topical if you have any allergies (especially to plants), or if you have a serious medical condition.Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.Do not take by mouth. Topical medicine is for use only on the skin.Do not use this medicine on open wounds or on sunburned, windburned, dry, chapped, or irritated skin. If this medicine gets in your eyes, nose, mouth, rectum, or vagina, rinse with waterMake sure your skin is clean and dry before you apply capsaicin topical.When using the cream or lotion, apply a thin layer to the affected area and rub in gently until completely absorbed.Capsaicin topical may be used up to 4 times daily or as directed on the medicine label.To apply a capsaicin topical skin patch, remove the liner and apply the patch to your skin over the area of pain. Press the edges firmly into place. Remove the patch and apply a new patch 1 or 2 times daily if needed.Wash your hands with soap and water immediately after applying capsaicin topical or handling the skin patch. If you have applied the medicine to your hands or fingers to treat pain in those areas, wait at least 30 minutes before washing your hands.To keep the medication from getting on your fingers when you apply it, you may use a rubber glove, finger cot, cotton ball, or clean tissue to apply the medicine.If the burning sensation is painful or causes significant discomfort, wash the treated skin area with soap and cool wateAvoid taking a bath or shower within 1 hour before or after you apply capsaicin to your skin. Also avoid swimming or vigorous exercise. Warm water or perspiration can increase the burning sensation caused by capsaicin.Avoid getting capsaicin topical in your eyes or near your nose where you might inhale it. If it does get into any of these areas, rinse thoroughly with water.Also avoid getting this medication on contact lenses, dentures, and other items that come into contact with sensitive areas of your body.
• Call your doctor if your pain does not improve after using this medication for 7 days, or if your symptoms get worse or get better and then come back in a few days.
• Store capsaicin topical at room temperature away from moisture and heat, in a place where children and pets cannot get to it.
• Capsaicin topical liquid is flammable. Do not use or store near fire or open flame.

Symptoms of Overdosage

ACECLOFENAC over-dosage can result in: Abdomen Pain, Nausea, Head Headache, Dizziness, Drowsiness
CAPSAICIN over-dosage can result in: Skin Irritation

Common Side-Effects

ACECLOFENAC : Osteoarthritis, Rheumatoid Arthritis, Ankylosing Spondylitis, Head Headache, Nausea, Vomit, Drowsiness, Dizziness
CAPSAICIN : Muscle Pain, Vomiting, Dizziness, Sore Throat, Chronic Cough, Difficulty Breathing, Shortness Of Breath, Cough, Throat Soreness, Wheezing, Eyes Blurred Vision, Fever

Serious Side-Effects

ACECLOFENAC : Black (tar) Colored Stools, Bloody Or Red Colored Stools, Wheezing
CAPSAICIN : Itchy Skin, Dry Skin

Food Interactions

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Technical Classification

ACECLOFENAC is categorized as: NONSTEROIDAL ANTI-INFLAMMATORY AGENTS / ANALGESICS / CENTRAL NERVOUS SYSTEM AGENTS
CAPSAICIN is categorized as: MISCELLANEOUS TOPICAL AGENTS / DERMATOLOGICAL AGENTS / TOPICAL AGENTS

Available Alternatives for PEALE GEL

What are the commonly available Substitutes?

PEALE GEL

INR 58.46 for 30 GM GEL

METHYL SALICYLATE 10.0 %W/W, MENTHOL 5.0 %W/W, ACECLOFENAC 1.5 %W/W, CAPSAICIN 0.01 %W/W

What are the other drugs with similar Ingredients?

CATERPIL 30GM GEL	INR 89 for 1 GEL	METHYL SALICYLATE 10 %W/W, MENTHOL 5 %W/W, LINSEED OIL 3 %W/W, CAMPHOR 3.1 %W/W, ACECLOFENAC 1.5 %W/W, CAPSAICIN 0.01 %W/W
DOLOWIN GEL GEL	INR 59 for 30 GM	METHYL SALICYLATE 10 %W/W, MENTHOL 5 %W/W, LINSEED OIL 3 %W/W, ACECLOFENAC 1.5 %W/W, CAPSAICIN 0.01 %W/W