SAFEGUARD 50MG/100MCG TAB

Overview

SAFEGUARD 50MG/100MCG TAB is a Schedule X drug.

SAFEGUARD 50MG/100MCG TAB is composed of: MISOPROSTOL (100.0 MCG), DICLOFENAC SODIUM (50.0 MG)

Misoprostol increases contractions of the uterus to cause abortion. It can also prevent post-delivery bleeding due to poor contraction of the uterus. Misoprostol is used in medical abortion and post-delivery bleeding. Misoprostol reduces stomach acid and helps protect the stomach from damage that can be caused by taking a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others. Misoprostol is used to prevent stomach ulcers during treatment with aspirin or an NSAID.

Diclofenac Sodium is an anti-inflammatory painkiller. This non-steroidal drug is used to alleviate symptoms of arthritis such as inflammation, pain, fever and swollen joints. It is used in the treatment of conditions such as rheumatoid arthritis, osteoarthritis, ankylosing spondylosis and severe menstrual pain. Diclofenac Sodium works by obstructing the production of cyclooxygenase, which synthesizes the compound called prostaglandin. This compound is responsible for symptoms of arthritis such as pain, swelling and inflammation. .

Usage

MISOPROSTOL is generally used to treat: Ulcer, Stomach, Postpartum Hemorrage

DICLOFENAC SODIUM is generally used to treat: Rheumatoid Arthritis, Osteoarthritis, Ankylosing Spondylitis, Menstrual Cramp, Pain
DICLOFENAC SODIUM can address symptoms like: Fever, Knees Joint Pain

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 18yrs

Q: Can it be taken during pregnancy?
A: Dangerous – Studies indicate Human-Fetal Risk

How Do I Take It?

SAFEGUARD 50MG/100MCG TAB is generally taken With Food.

Precautions for SAFEGUARD 50MG/100MCG TAB and its Constituents


It may cause abortion, premature birth, or birth defects, uterine rupture; it should not be used during pregnancy. Caution should be exercised in patients with history of low blood pressure, which may lead to severe complications e.g. brain or heart disease, inflammatory bowel disease and kidney impairment, elderly, children. It may lead to dehydration, drink adequate water.
  • Pregnant women, women trying to conceive, smokers and alcoholics should avoid taking Diclofenac Sodium, since it can have harmful effects.
  • Avoid taking aspirin or other NSAIDs while you are taking this medicine.
  • If you use diclofenac long-term, you may need frequent medical tests.
  • Take Diclofenac sodium on an empty stomach, at least 1 hour before or 2 hours after a meal.
  • Do not crush, chew, or break an extended-release tablet or delayed-release tablet. Swallow it whole.
  • Dissolve diclofenac sodium powder in to 2 ounces of water. Do not use any other type of liquid. Stir this mixture and drink all of it right away. It works best if you take it on an empty stomach.
  • It is not known whether diclofenac passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.
  • Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft).

Symptoms of Overdosage

MISOPROSTOL over-dosage can result in: Difficulty Breathing, Drowsiness, Seizures (uncontrollable Jerking Of Limbs), Dizziness, Irregular Heartbeat
DICLOFENAC SODIUM over-dosage can result in: Abdomen Pain, Vomit, Drowsiness, Difficulty Breathing, Seizures (uncontrollable Jerking Of Limbs)

Common Side-Effects

MISOPROSTOL : Nausea, Abdomen Stomach Cramps, Dizziness, Decreased Urination, Mood Swings, Weakness (generalized), Irregular Heartbeat
DICLOFENAC SODIUM : Skin Rash, Itchy Skin, Indigestion, Abdomen Bloating Or Fullness, Abdomen Burn, Abdomen Pain, Belching, Black (tar) Colored Stools, Cloudy Urine With Strong Odor, Constipation, Loose Motion, Dizziness, Head Headache, Loss Of Appetite, Nausea, Vomit, Pale Skin, Fatigue (tiredness), Weakness (generalized), Weight Loss (unintentional)

Serious Side-Effects

MISOPROSTOL : Irregular Menstrual Periods, Vaginal Bleeding Between Periods

Rare Side-Effects

MISOPROSTOL : Difficulty Breathing, Face Swelling, Dizziness

Disease Interactions

DICLOFENAC SODIUM can interfere with: Asthma, Congestive Heart Disease, Urine Retention, Hypertension, Peptic Ulcer, Duodenitis, Intestinal Perforation, Alcoholism, Colitis, Gastroenteritis, Dermatitis, Acute Renal Failure, Hyponatremia, Acute Liver Failure, Myocardial Infarction, Ischemic Heart Disease, Porphyria, Anemia, Hyperkalemia, Thrombocytopathy, Thrombocytopenia, Vitamin K Deficiency

Technical Classification

MISOPROSTOL is categorized as: MISCELLANEOUS GI AGENTS / GASTROINTESTINAL AGENTS
DICLOFENAC SODIUM is categorized as: NONSTEROIDAL ANTI-INFLAMMATORY AGENTS / ANALGESICS / CENTRAL NERVOUS SYSTEM AGENTS

Available Alternatives for SAFEGUARD 50MG/100MCG TAB

What are the commonly available Substitutes?

SAFEGUARD 50MG/100MCG TABINR 81 for 10 TABLETSMISOPROSTOL 100.0 MCG, DICLOFENAC SODIUM 50.0 MG

What are the other drugs with similar Ingredients?

MIDICLO 50MG/200MG TABINR 76.22 for 6 TABLETSMISOPROSTOL 200.0 MG, DICLOFENAC SODIUM 50.0 MG
MIFENAC TABINR 99 for 10 TABLETSMISOPROSTOL 100 MCG, DICLOFENAC SODIUM 50 MG
MISONAC 100MG/0.1MG TAB SRINR 154.3 for 10 TABLET SRDICLOFENAC SODIUM 100.0 MG, MISOPROSTOL 0.1 MG
MISONAC 50MG/0.1MG TABINR 127 for 10 TABLETSDICLOFENAC SODIUM 50.0 MG, MISOPROSTOL 0.1 MG
MISONAC TABINR 90.1 for 10 TABLETMISOPROSTOL 100 MCG, DICLOFENAC SODIUM 50 MG
MISONAC-SR TABINR 100 for 10 TABLET SRMISOPROSTOL 100 MCG, DICLOFENAC SODIUM 100 MG
SAFEGUARD 100MG/200MCG TAB SRINR 164 for 15 TABLET SRMISOPROSTOL 200.0 MCG, DICLOFENAC SODIUM 100.0 MG
SAFEGUARD 75MG/200MCG TABINR 148 for 15 TABLETSMISOPROSTOL 200.0 MCG, DICLOFENAC SODIUM 75.0 MG