SIMBRINZA EYE-DPS

Overview

SIMBRINZA EYE-DPS is an Over-the-counter (OTC) drug.

SIMBRINZA EYE-DPS is composed of: BRINZOLAMIDE (10 MG/ML), BRIMONIDINE (2 MG/ML)

Brinzolamide is used to treat high pressure inside the eye due to glaucoma (open angle-type) or other eye diseases (e.g., ocular hypertension). Lowering high pressure inside the eye helps to prevent blindness. This medication works by decreasing the amount of fluid within the eye. It belongs to a class of drugs known as Carbonic anhydrase inhibitors.


Brimonidine belongs to a group of drugs called alpha adrenergic agonists. The eye drops work by decreasing the amount of fluid produced in the eyes. The gel form works by reducing the amount of blood flow to the facial area. Decreasing blood flow may reduce overall redness associated with rosacea. Brimonidine ophthalmic (for the eyes) is used to treat open-angle glaucoma or ocular hypertension (high pressure inside the eye).

Usage

BRINZOLAMIDE is generally used to treat: Open-Angle Glaucoma, Glaucoma

BRIMONIDINE is generally used to treat: Glaucoma, Rosacea, Open-Angle Glaucoma

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Ask your doctor

Q: Can it be taken during pregnancy?
A: Not enough studies to prove Risk – Ask your Doctor

Precautions


  • Before using brinzolamide, tell your doctor or pharmacist if you are allergic to it or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
  • Before using this medication, tell your doctor or pharmacist your medical history, especially of other eye conditions, kidney problems, liver disease.
  • If you develop an eye infection or injury, or have eye surgery, check with your doctor about whether you should continue to use your current bottle of brinzolamide.
  • Your vision may be temporarily blurred or unstable after applying this drug. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.
  • This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.
  • It is unknown if this drug passes into breast milk. Because of the potential risk to the infant, consult your doctor before breast-feeding.

  • Before using this medication, tell your doctor or pharmacist your medical history, especially of blood circulation disorders (cerebral or coronary insufficiency), heart disease, depression, Raynaud’s disease, low blood pressure upon standing (orthostatic hypotension), a certain immune system disorder (Sjogren’s syndrome), a certain skin/connective tissue disease (scleroderma).
  • Avoid certain triggers that may worsen rosacea such as wind, hot beverages, spicy foods, alcohol, and extreme cold. Discuss with your doctor.
  • Sun exposure can worsen rosacea. Limit exposure to the sun by wearing a wide-brimmed hat and using a sunscreen that is SPF 15 or greater.
  • Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
  • During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
  • It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Symptoms of Overdosage

BRINZOLAMIDE over-dosage can result in: Difficulty Breathing

Common Side-Effects

BRINZOLAMIDE : Skin Rash, Eyes Discharge Or Mucus, Eyes Dry Eyes, Eyes Redness, Eyes Soreness, Eyes Eye Irritation
BRIMONIDINE : Itchy Skin, Depression, Skin Rash, Eyes Pain, Eyes Blindness, Eyes Bleeding, Confusion, Dizziness, Fainting, Irregular Heartbeat, Eyes Watery Eyes, Vomit, Fatigue (tiredness), Body Excessive Sweating, Sneezing, Runny Nose, Nausea, Depressed Mood

Serious Side-Effects

BRINZOLAMIDE : Eyes Blurred Vision
BRIMONIDINE : Eyes Blurred Vision, Eyes Burning Sensation, Eyes Double Vision (without One Eye Covered), Head Headache

Rare Side-Effects

BRINZOLAMIDE : Hives, Chest Pain, Cough, Difficulty Swallowing, Dizziness, Eyes Double Vision (with One Eye Covered), Eyes Redness, Rapid Heart Rate (pulse), Shortness Of Breath, Throat Soreness, Fatigue (tiredness), Wheezing

Disease Interactions

BRIMONIDINE can interfere with: Depression, Acute Liver Failure, Acute Kidney Failure

Technical Classification

BRINZOLAMIDE is categorized as: OPHTHALMIC GLAUCOMA AGENTS / OPHTHALMIC PREPARATIONS / TOPICAL AGENTS
BRIMONIDINE is categorized as: OPHTHALMIC GLAUCOMA AGENTS / OPHTHALMIC PREPARATIONS / TOPICAL AGENTS

Available Alternatives

What are the commonly available Substitutes?

SIMBRINZA EYE-DPSINR 495 for 5MLBRINZOLAMIDE 10 MG/ML, BRIMONIDINE 2 MG/ML