SKYRYL PLUS TAB

Overview

SKYRYL PLUS TAB is a Schedule H drug.

SKYRYL PLUS TAB is composed of: PARACETAMOL (500.0 MG), NIMESULIDE (100.0 MG), CAFFEINE (25.0 MG), PHENYLEPHRINE (10.0 MG), CETIRIZINE (5.0 MG)

Paracetamol is a pain reliever and a fever reducer. The exact mechanism of action of is not known. Paracetamol is used to treat many conditions such as a headache, muscle aches, arthritis, backache, toothaches, colds, and fevers. It relieves pain in mild arthritis but has no effect on the underlying inflammation and swelling of the joint.


Caffeine is a central nervous system stimulant. It works by stimulating the brain. Caffeine is found naturally in foods and beverages such as coffee, tea, colas, energy and chocolate. Botanical sources of caffeine include kola nuts, guarana, and yerba mate. Caffeine is also available in prescription and non-prescription medications. Caffeine is used to restore mental alertness or wakefulness during fatigue or drowsiness. Caffeine is also found in some headache and migraine medications, in certain dietary supplements used for weight loss, and in many popular energy drinks.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose). Phenylephrine is used to treat nasal and sinus congestion or congestion of the tubes that drain fluid from your inner ears called the eustachian (yoo-STAY-shun) tubes.

Cetirizine is an anti histamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, Itching, watery eyes and runny nose. It is used to treat cold.

Usage

PARACETAMOL is generally used to treat: Arthritis
PARACETAMOL can address symptoms like: Head Headache, Back Pain, Cold, Fever


CAFFEINE is generally used to treat: Migraine
CAFFEINE can address symptoms like: Weakness (generalized), Fatigue (tiredness), Drowsiness, Head Headache

PHENYLEPHRINE can address symptoms like: Nasal Congestion

CETIRIZINE is generally used to treat: Runny Nose And Dry Cough, Common Cold
CETIRIZINE can address symptoms like: Sneezing

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 1month

Q: Can it be taken during pregnancy?
A: Not enough studies to prove Risk – Ask your Doctor

Q: Is it safe to take for someone breastfeeding?
A: Not Safe

How Do I Take It?

SKYRYL PLUS TAB is generally taken After Food.

Precautions for SKYRYL PLUS TAB and its Constituents

Caution should be exercised in patients with history of asthma, bleeding problems, growths in the nose, heart, kidney or liver disease, liver inflammation, high blood pressure, chickenpox, anxiety, trouble in sleeping, ulcers, stomach problems, stroke, Kawasaki syndrome, any allergy, who are taking other medications, during pregnancy and breastfeeding. Avoid alcohol consumption. It should not be used in children with infections such as flu, chickenpox or viral infections. Avoid large amount of caffeinated beverages while taking this medication. It may reduce platelet counts; avoid injury or bruising.

While taking this medication avoid drinking excess amount of caffeine containing drinks.  Though caffeine may increase alertness, it can cause dizziness. Hence avoid doing anything that requires concentration and can cause disability or death in case of an accident, e.g. driving a car or operating machinery. It is not to be used as a substitute for sleep. Caution should be exercised in patients with history of heart disease, kidney disease, liver disease, stomach problems (peptic ulcer), seizures, during pregnancy and breast feeding.
Do not give phenylephrine containing products to children younger than 4 years of age. It may cause serious side effects or cause of death in children. Do not use this medication for longer duration, it may cause rebound congestion in prolonged or excessive use of nasal or eye drops. Caution should be exercised in patients with history of severe increase in thyroid hormone, severe heart disease, diabetes, prostate enlargement, during pregnancy and breastfeeding.
Caution should be exercised in patients with history of kidney and liver disease.
It may cause drowsiness, so don’t Drive while taking this medication.

Symptoms of Overdosage

PARACETAMOL over-dosage can result in: Loss Of Appetite, Nausea, Vomit, Abdomen Pain, Weakness (generalized), Upper Abdomen Pain, Dark Colored (brown) Urine, Eyes Yellow Eyes
CAFFEINE over-dosage can result in: Anxiety, Confusion, Frequent Urination, Irregular Heartbeat, Arms Muscle Twitching (painless), Ringing In Ears, Seizures (uncontrollable Jerking Of Limbs), Abdomen Pain, Difficulty Sleeping
CETIRIZINE over-dosage can result in: Drowsiness, Restless Or Irritability

Common Side-Effects

CAFFEINE : Enterocolitis, Confusion, Dizziness, Restless Or Irritability, Nervousness, Depressed Mood, Fatigue (tiredness), Head Headache, Lightheadedness, Seizures (uncontrollable Jerking Of Limbs), Irregular Heartbeat, Vomit, Nausea, Frequent Urination, Difficulty Breathing
PHENYLEPHRINE : Hives, Skin Rash, Blood Pressure, High, Body Itching, Irregular Heartbeat, Difficulty Sleeping, Eyes Blurred Vision, Chest Discomfort, Wheezing, Shortness Of Breath, Nervousness, Head Headache, Restless Or Irritability, Seizures (uncontrollable Jerking Of Limbs)
CETIRIZINE : Dizziness, Diarrhoea, Abdominal Pain, Pharyngitis, Rhinitis, Insomnia, Chronic Fatigue Disorder, Head Headache

Serious Side-Effects

CETIRIZINE : Dyspepsia, Abdomen Pain

Rare Side-Effects

PARACETAMOL : Skin Rash, Dizziness, Difficulty Breathing, Face Swelling, Body Itching
CETIRIZINE : Paresthesia, Constipation, Flatulence, Tinnitus, Fever, Restless Or Irritability

Disease Interactions

CETIRIZINE can interfere with: Acute Renal Failure, Acute Liver Failure

Technical Classification

PARACETAMOL is categorized as: MISCELLANEOUS ANALGESICS / ANALGESICS / CENTRAL NERVOUS SYSTEM AGENTS
CAFFEINE is categorized as: CNS STIMULANTS / CENTRAL NERVOUS SYSTEM AGENTS
PHENYLEPHRINE is categorized as:

• DECONGESTANTS / RESPIRATORY AGENTS
• VASOPRESSORS / CARDIOVASCULAR AGENTS

CETIRIZINE is categorized as: THIRD GENERATION CEPHALOSPORINS / CEPHALOSPORINS / ANTI-INFECTIVES

Available Alternatives for SKYRYL PLUS TAB

What are the commonly available Substitutes?

SINOCOLD PLUS TAB	INR for	PARACETAMOL 500 MG, NIMESULIDE 100 MG, CAFFEINE 25 MG, PHENYLEPHRINE 10 MG, CETIRIZINE 5 MG
SKYRYL PLUS TAB	INR 49 for 10 TABLETS	PARACETAMOL 500.0 MG, NIMESULIDE 100.0 MG, CAFFEINE 25.0 MG, PHENYLEPHRINE 10.0 MG, CETIRIZINE 5.0 MG

What are the other drugs with similar Ingredients?

COLDCIZ PLUS 5MG/30MG/100MG/375MG/5MG TAB	INR 47.13 for 10 TABLETS	PARACETAMOL 375.0 MG, NIMESULIDE 100.0 MG, CETIRIZINE 30.0 MG, CAFFEINE 5.0 MG, PHENYLEPHRINE 5.0 MG
MAXTRA COLD TAB	INR 49.5 for 10 TABLETS	PARACETAMOL 325.0 MG, NIMESULIDE 100.0 MG, CAFFEINE 25.0 MG, PHENYLEPHRINE 10.0 MG, CETIRIZINE 5.0 MG
NICIP COLD & FLU TAB	INR 51.5 for 10 TABLETS	PARACETAMOL 325.0 MG, NIMESULIDE 100.0 MG, CAFFEINE 25.0 MG, CETIRIZINE 5.0 MG, PHENYLEPHRINE 5.0 MG
NIMUPAN COLD FLU TAB	INR 43 for 10 TABLETS	PARACETAMOL , CETIRIZINE , NIMESULIDE , PHENYLEPHRINE , CAFFEINE
NIMUTAL COLD TAB	INR 55 for 10 TABLETS	PHENYLEPHRINE , PARACETAMOL , NIMESULIDE , CETIRIZINE , CAFFEINE
SNEEZY COLD & FLU TAB	INR 45 for 10 TABLETS	PARACETAMOL 325.0 MG, NIMESULIDE 100.0 MG, CAFFEINE 25.0 MG, CETIRIZINE 5.0 MG, PHENYLEPHRINE 5.0 MG