TOBRACEF 1000MG/120MG INJ

Overview

TOBRACEF 1000MG/120MG INJ is a Schedule H1 antibiotic.

TOBRACEF 1000MG/120MG INJ is composed of: CEFTAZIDIME (1000.0 MG), TOBRAMYCIN SULFATE (120.0 MG)

Ceftazidime is a prescription medication used to treat bacterial infections, including lung, skin, bone, joint, brain, stomach, blood, urinary tract, and gynecological infections. Ceftazidime belongs to a group of drugs called cephalosporin antibiotics, which work to stop the growth of bacteria in the body. Common side effects of ceftazidime include irritation at the site of injection, rash, nausea, diarrhea, and vomiting.
Tobramycin is an aminoglycoside antibiotic. Tobramycin fights infections that are caused by bacteria.Tobramycin injection is used to treat bacterial infections of the skin, heart, stomach, brain and spinal cord, lungs, and urinary tract (bladder and kidneys). It is also used in the treatment of cystic fibrosis. Tobramycin injection is sometimes used together with other antibiotics. It stops bacterial growth by preventing synthesis of essential proteins required by bacteria to carry out vital functions.

Usage

CEFTAZIDIME is generally used to treat: Bacterial Infection, Deep Skin Infection, Urinary Tract Infection

TOBRAMYCIN SULFATE is generally used to treat: Cystic Fibrosis, Bacterial Infection, Meningitis
TOBRAMYCIN SULFATE can address symptoms like: Cough, Wheezing, Shortness Of Breath, Fatigue (tiredness), Weakness (generalized), Abdomen Pain

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 1month

Q: Can it be taken during pregnancy?
A: Considered as Generally Safe – not enough studies to prove risk

Q: Is it safe to take for someone breastfeeding?
A: Not Safe

Precautions for TOBRACEF 1000MG/120MG INJ and its Constituents

• It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
• Ceftazidime can make birth control pills less effective. Ask your doctor about using non hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy.
• Ceftazidime can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
• Before using ceftazidime, tell your doctor or pharmacist if you are allergic to it or to other antibiotics (such as penicillins, other cephalosporins) or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
• Before using this medication, tell your doctor or pharmacist your medical history, especially of kidney disease, stomach/intestinal diseases (such as colitis).
• Ceftazidime may cause live bacterial vaccines (such as typhoid vaccine) to not work as well. Do not have any immunizations/vaccinations while using this medication unless your doctor tells you to.
• Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

• You should not use tobramycin if you are allergic to tobramycin.
• Do not use tobramycin if you are pregnant.
• Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.
• Tobramycin is inhaled into the lungs with the use of a nebulizer or an inhaler device.
• Do not swallow the medicine by mouth.
• Do not use tobramycin inhalation solution if it looks cloudy or has particles in it.
• Do not use extra medicine to make up the missed dose.
• Do not mix tobramycin solution with dornase alfa in the nebulizer.It may lead to dehydration, drink adequate fluid.
• Avoid long-term use of this medication; otherwise it will cause secondary infection.
• Take full course of treatment and avoid excess dosage.
• Monitor kidney function, hearing tests, blood electrolyte levels regularly while taking this medication.
• Do not use contact lenses when on treatment with tobramycin eye drops.

Symptoms of Overdosage

CEFTAZIDIME over-dosage can result in: Seizures (uncontrollable Jerking Of Limbs)
TOBRAMYCIN SULFATE over-dosage can result in: Body Discoloration, Fingers Blue Colored Skin, Dizziness, Drowsiness, Lightheadedness, Slow Or Irregular Breathing, Hallucinations, Spinning Sensation

Common Side-Effects

CEFTAZIDIME : Diarrhoea, Vaginal Discharge, Vaginitis, Diaper Rash, Itchy Skin, Skin Rash, Abdomen Bloating Or Fullness, Fever, Increased Thirst, Nausea, Vomit, Pain With Sexual Intercourse (male), Pain With Sexual Intercourse (female), Left Foot Swelling, Right Foot Swelling, Legs Swelling, Weight Loss (unintentional)
TOBRAMYCIN SULFATE : Diarrhoea, Skin Rash, Hearing Loss, Cough, Throat Soreness, Hoarse Voice, Noisy Breathing, Decreased Taste, Fever, Head Headache, Runny Nose, Sneezing, Loss Of Voice, Chills, Back Pain, Body Discomfort

Serious Side-Effects

CEFTAZIDIME : Abdomen Pain, Loose Motion, Confusion, Seizures (uncontrollable Jerking Of Limbs)
TOBRAMYCIN SULFATE : Hearing Loss, Nosebleeds, Acute Kidney Failure, Colored Sputum, Difficulty Breathing, Chest Pain, Black (tar) Colored Stools, Ringing In Ears, Pain With Urination, Difficulty Urinating, Shortness Of Breath, Chest Discomfort, Easy Bleeding

Rare Side-Effects

CEFTAZIDIME : Chest Pain, Abdomen Pain, Legs Pain, Body Burning Sensation, Chills, Cough, Dark Colored (brown) Urine, Difficulty Breathing, Difficulty Swallowing, Dizziness, Rapid Heart Rate (pulse), Head Headache, Loss Of Appetite, Pale Skin, Shortness Of Breath, Throat Soreness, Wheezing, Eyes Yellow Eyes

Disease Interactions

TOBRAMYCIN SULFATE can interfere with: Diarrhoea, Vomiting, Botulism, Hypocalcemia, Myoneural Disorders, Parkinsonism, Hearing Loss, Tinnitus, Acute Renal Failure

Technical Classification

CEFTAZIDIME is categorized as: THIRD GENERATION CEPHALOSPORINS / CEPHALOSPORINS / ANTI-INFECTIVES
TOBRAMYCIN SULFATE is categorized as:

• AMINOGLYCOSIDES / ANTI-INFECTIVES
• INHALED ANTI-INFECTIVES / RESPIRATORY INHALANT PRODUCTS / RESPIRATORY AGENTS

Available Alternatives for TOBRACEF 1000MG/120MG INJ

What are the commonly available Substitutes?

TOBRACEF 1000MG/120MG INJ

INR 450 for 10 ML INJECTION

CEFTAZIDIME 1000.0 MG, TOBRAMYCIN SULFATE 120.0 MG