TOPISONE M CRM

Overview

TOPISONE M CRM is a Schedule H drug.

TOPISONE M CRM is composed of: MICONAZOLE (2.0 %W/W), CHLOROCRESOL (0.1 %W/W), CLOBETASOL PROPIONATE (0.05 %W/W)

Miconazole is an antifungal medicine that fights infections caused by fungus.Miconazole buccal is a pill placed between your check and gum to treat candida (yeast) infections inside the mouth.
It kills fungi by destroying the fungal cell membrane. This treats your infection.



Clobetasol is a highly potent steroid. It reduces the actions of chemicals in the body that cause inflammation. Clobetasol topical (for the skin) is used to treat the inflammation and itching caused by a number of skin conditions such as allergic reactions, eczema, and psoriasis.

Usage

MICONAZOLE is generally used to treat: Fungal Infection, Yeast Infection, Athlete’s Foot, Jock Itch, Vaginal Candidiasis


CLOBETASOL PROPIONATE is generally used to treat: Eczema, Psoriasis

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 12yrs

Q: Can it be taken during pregnancy?
A: Not enough studies to prove Risk – Ask your Doctor

Q: Is it safe to take for someone breastfeeding?
A: Check with your Doctor first

Precautions for TOPISONE M CRM and its Constituents

• Follow all directions on your medicine label and package.You should not use this medicine if you are allergic to miconazole (Monistat, Vusion, and others) or if you are allergic to milk proteins.
• Do not use this medicine in larger or smaller amounts or for longer than recommended.
• The usual dose of this medicine is one tablet each morning for 14 days in a row.
• Brush your teeth before putting in a buccal tablet.
• Make sure your hands are dry before handling the tablet.
• Do not chew or swallow the buccal tablet. Leave it in place until the next morning.
• Avoid touching or pressing the tablet while it is in place.
• You may eat and drink normally while the tablet is in place, but avoid chewing gum.If any pieces of the tablet remain in your mouth the next morning, rinse your mouth with water before using a new tablet.
• Avoid wearing an upper denture if it gets in the way of the buccal tablet.Do not skip any doses and finish the full course of treatment even if you feel better.
• Avoid contact with your eyes.

Do not use clobetasol topical to treat any condition that has not been checked by your doctor. Avoid using clobetasol topical to treat skin on your face, underarms, or groin area without your doctor’s advice. Avoid getting this medicine in your eyes. If contact does occur, rinse with water. Do not use clobetasol topical on broken or infected skin. Also avoid using this medicine in open wounds.

Symptoms of Overdosage

CLOBETASOL PROPIONATE over-dosage can result in: Easy Bruising

Common Side-Effects

MICONAZOLE : Pain, Diarrhoea, Itchy Skin, Toothache, Abdomen Pain, Loss Of Appetite, Weakness (generalized), Upper Abdomen Pain, Head Headache, Nausea, Dry Mouth, Decreased Taste, Gums Redness, Body Pain, Fever, Chills, Nasal Congestion, Pale Skin, Runny Nose, Sneezing, Throat Soreness, Fatigue (tiredness)
CLOBETASOL PROPIONATE : Excessive Body Hair Growth, Body Itching

Serious Side-Effects

MICONAZOLE : Difficulty Breathing, Pain With Urination, Tongue Soreness

Rare Side-Effects

MICONAZOLE : Mouth Ulcer, Black (tar) Colored Stools, Shortness Of Breath, Mouth Soreness
CLOBETASOL PROPIONATE : Folliculitis, Skin Rash, Fatigue (tiredness), Weight Loss (unintentional), Head Headache, Ankles Swelling, Increased Thirst, Frequent Urination, Dizziness, Difficulty Breathing, Face Swelling

Disease Interactions

CLOBETASOL PROPIONATE can interfere with: Impaired Glucose Tolerance, Diabetes Mellitus, Diaper Rash, Hyperadrenalism, Acute Liver Failure, Bacterial Infection, Fungal Infection, Viral Inection, Protozoal Infection, Cataract, Glaucoma

Technical Classification

MICONAZOLE is categorized as: AZOLE ANTIFUNGALS / ANTIFUNGALS / ANTI-INFECTIVES
CLOBETASOL PROPIONATE is categorized as: TOPICAL STEROIDS / DERMATOLOGICAL AGENTS / TOPICAL AGENTS

Available Alternatives for TOPISONE M CRM

What are the commonly available Substitutes?

TOPISONE M CRM

INR 75 for 15 GM CREAM

MICONAZOLE 2.0 %W/W, CLOBETASOL PROPIONATE 0.05 %W/W, CHLOROCRESOL 0.1 %W/W

What are the other drugs with similar Ingredients?

CLOBID NM OINT	INR 100 for 15 GM OINTMENT	MICONAZOLE 2.0 %W/W, NEOMYCIN 0.5 %W/W, CLOBETASOL PROPIONATE 0.05 %W/W, CHLOROCRESOL 0.1 %W/W
DERMOCRAT PLUS CRM	INR 46 for 20 GM CREAM	MICONAZOLE 2.0 %W/W, NEOMYCIN 0.5 %W/W, CLOBETASOL PROPIONATE 0.05 %W/W, CHLOROCRESOL 0.1 %W/W