TRIGAINE SOLN

Overview

TRIGAINE SOLN is a Schedule H drug.

TRIGAINE SOLN is composed of: MINOXIDIL (2.0 %W/V), AZELAIC ACID (1.5 %W/V), TRETINOIN (0.025 %W/V)

Minoxidil is a vasodilator that relaxes (widens) blood vessels and improves blood flow. Minoxidil is used to treat severe high blood pressure (hypertension) that is causing symptoms or damaging your vital organs. Minoxidil is usually given together with two other medicines to help prevent serious side effects.

Azelaic acid is a naturally occurring acid. It helps the skin to renew itself more quickly and therefore reduces pimple and blackhead formation. It also helps to kill the bacteria that cause acne and rosacea.Azelaic acid topical (for the skin) is used to treat acne and rosacea.Azelaic acid works by killing the acne-causing bacteria and reduces inflammation (redness and swelling) of the skin.


Usage

MINOXIDIL is generally used to treat: Hypertension

AZELAIC ACID is generally used to treat: Acne, Rosacea


Frequently Asked Questions

Q: Is it safe on my liver?
A: Check with your Doctor first

Q: Is it safe on my kidney?
A: Check with your Doctor first

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Ask your doctor

Q: Can it be taken during pregnancy?
A: Not enough studies to prove Risk – Ask your Doctor

Q: Is it safe to take for someone breastfeeding?
A: Not Safe

Precautions for TRIGAINE SOLN and its Constituents


Caution should be exercised in patients with history of heart disease, a heart attack, pheochromocytoma, or kidney disease, any allergy, who are taking other medications, during pregnancy and breastfeeding. It may cause dizziness, lightheadedness or changes in vision, do not drive a car or operate machinery while taking this medication. Avoid alcohol consumption.
  •  If you have a sensitive skin, you should apply Azelaic acid only once a day for the first week of treatment and then proceed to twice daily applications.

  • You should not use Azelaic acid for more than 12 months at any time. Before applying the cream/gel, clean the skin thoroughly with plain water and make it dry.

  • Azelaic acid is for external use on the skin only. You should not allow Azelaic acid to come into contact with your eyes, mouth or other inner skin layer (mucous membranes). If it does, wash immediately with large amounts of cool water.
  • Use Azelaic acid with caution if you have asthma, as worsening of symptoms has been reported.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.
  • You should not use this medication if you are allergic to azelaic acid or propylene glycol.
  • Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.Wash your hands before and after applying this medication.
  • Clean the affected area with a mild soap or a soap-free cleansing lotion and pat dry with a soft towel. Apply the medication as directed.
  • Azelaic acid topical is usually applied twice daily, in the morning and at bedtime. Follow your doctor’s instructions.

Symptoms of Overdosage

MINOXIDIL over-dosage can result in: Dizziness, Fainting
AZELAIC ACID over-dosage can result in: Difficulty Breathing

Common Side-Effects

MINOXIDIL : Lightheadedness
AZELAIC ACID : Dry Skin, Itchy Skin, Body Burning Sensation, Pale Skin

Serious Side-Effects

MINOXIDIL : Irregular Heartbeat, Ankles Swelling, Fatigue (tiredness), Weight Gain
AZELAIC ACID : Skin Rash

Rare Side-Effects

MINOXIDIL : Skin Rash, Difficulty Breathing, Body Itching, Face Swelling
AZELAIC ACID : Dizziness, Eyes Blurred Vision, Eyes Pain, Eyes Redness

Technical Classification

MINOXIDIL is categorized as: VASODILATORS / CARDIOVASCULAR AGENTS
AZELAIC ACID is categorized as:
  • TOPICAL ACNE AGENTS / DERMATOLOGICAL AGENTS / TOPICAL AGENTS
  • TOPICAL ANTI-ROSACEA AGENTS / DERMATOLOGICAL AGENTS / TOPICAL AGENTS

Available Alternatives for TRIGAINE SOLN

What are the commonly available Substitutes?

SHALTOP A SOLNINR 216 for 60 ML SOLUTIONMINOXIDIL 2.0 %W/V, AZELAIC ACID 1.5 %W/V, TRETINOIN 0.025 %W/V
TRIGAINE SOLNINR 339 for 60 ML SOLUTIONMINOXIDIL 2.0 %W/V, AZELAIC ACID 1.5 %W/V, TRETINOIN 0.025 %W/V

What are the other drugs with similar Ingredients?

MINOKEM N 2% LTNINR 332 for 60 ML SOLUTIONALCOHOL 65 %V/V, MINOXIDIL 2 %W/V, AZELAIC ACID 1.5 %W/V, TRETINOIN 0.01 %W/V
MINOKEM N 2% SOLNINR 365 for 60 ML SOLUTIONMINOXIDIL 2.0 %W/V, AZELAIC ACID 1.5 %W/V, TRETINOIN 0.01 %W/V