VIROCOMB E 150MG/300MG/600MG KIT

Overview

VIROCOMB E 150MG/300MG/600MG KIT is a Schedule H drug.

VIROCOMB E 150MG/300MG/600MG KIT is composed of: EFAVIRENZ (600.0 MG), ZIDOVUDINE (300.0 MG), LAMIVUDINE (150.0 MG)

Efavirenz is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body. Efavirenz is used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). Efavirenz is for adults and children who are at least 3 months old and weigh at least 8 pounds. Efavirenz is not a cure for HIV or AIDS.

Zidovudine is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body. Zidovudine is used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). Zidovudine is also given during pregnancy to prevent an HIV-infected woman from passing the virus to her baby. Zidovudine is not a cure for HIV or AIDS.
Lamivudine is an antiviral medication. It prevents the multiplication of the virus in human cells. This stops the virus from producing new viruses and clears up your infection. Lamivudine is used in the treatment of HIV infection and chronic hepatitis B virus (HBV) infection.

Usage

EFAVIRENZ is generally used to treat: AIDS

ZIDOVUDINE is generally used to treat: Human Immunodeficiency Virus, AIDS

LAMIVUDINE is generally used to treat: Hepatitis B, AIDS

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Check with your Doctor first

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 2yrs

Q: Can it be taken during pregnancy?
A: Studies indicate Risk – Doctor advice is must

Q: Is it safe to take for someone breastfeeding?
A: Check with your Doctor first

How Do I Take It?

VIROCOMB E 150MG/300MG/600MG KIT is generally taken Before Food.

Precautions


Efavirenz must be given in combination with other antiviral medications and it should not be used alone. Your disease may become resistant to efavirenz if you do not take it in combination with other HIV medicines your doctor has prescribed. Take efavirenz on an empty stomach at bedtime. To make swallowing easier, you may open an efavirenz capsule and sprinkle the medicine into a spoonful of applesauce, yogurt, or grape jelly. You may also mix the medicine with infant formula if you are giving the medicine to a baby. Swallow the mixture right away. Do not save it for later use. After taking efavirenz using the sprinkle method, do not eat for the next 2 hours. Efavirenz mixed with infant formula should be given to the baby right away. But do not feed the baby any more formula for at least 2 hours afterward. Efavirenz comes with instructions for mixing the capsule contents with soft food or infant formula. Follow these directions carefully. Do not crush, chew, or break an efavirenz tablet. Swallow it whole with liquid. Drinking alcohol can increase certain side effects of efavirenz. Taking this medication will not prevent you from passing HIV to other people. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.
Caution should be exercised in patients with history of bone marrow depression, low blood counts, liver, kidney diseases, obesity, any allergy, who are taking other medications, during pregnancy and breastfeeding. Avoid contact with people who have infections. Avoid sexual contact with your partner in order to avoid transmission of HIV infection. Monitor liver, kidney functions, and complete blood cell counts while taking this medication.
Caution should be exercised in patients with history of hepatitis B, kidney disease, pancreas disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.  It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication. Avoid alcohol consumption. It should not be used in children less than 2 years old. It may affect blood sugar level; monitor sugar level regularly while taking this medication. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.


Symptoms of Overdosage

EFAVIRENZ over-dosage can result in: Difficulty Breathing
LAMIVUDINE over-dosage can result in: Difficulty Breathing

Common Side-Effects

EFAVIRENZ : Depression, Skin Rash, Body Itching, Blood Or Red Colored Urine, Pain With Urination, Lower Back Pain
ZIDOVUDINE : Nausea, Head Headache, Vomit, Difficulty Sleeping, Loss Of Appetite
LAMIVUDINE : Nausea, Vomit, Loose Motion, Dizziness, Head Headache, Fatigue (tiredness)

Serious Side-Effects

ZIDOVUDINE : Guillan-Barre Syndrome, Goiter, Depression, Fever, Chills, Cough, Difficulty Breathing, Irregular Heartbeat, Anxiety, Confusion, Easy Bruising
LAMIVUDINE : Mood Swings, Nausea, Vomit, Abdomen Pain, Dark Colored (brown) Urine, Eyes Yellow Eyes

Rare Side-Effects

EFAVIRENZ : Hives, Abdomen Pain, Confusion, Seizures (uncontrollable Jerking Of Limbs), Cough, Dark Colored (brown) Urine, Fainting, Fever, Chills, Head Headache, Loss Of Appetite, Nausea, Vomit
ZIDOVUDINE : Skin Rash, Dizziness, Face Swelling, Body Itching
LAMIVUDINE : Rapid Breathing, Drowsiness, Hands Numbness

Disease Interactions

LAMIVUDINE can interfere with: Hyperlipidemia, Pancreatitis, Alcoholism, Acute Renal Failure

Technical Classification

EFAVIRENZ is categorized as: NNRTIS / ANTIVIRAL AGENTS / ANTI-INFECTIVES
ZIDOVUDINE is categorized as: NNRTIS / ANTIVIRAL AGENTS / ANTI-INFECTIVES
LAMIVUDINE is categorized as: NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS (NRTIS) / ANTIVIRAL AGENTS / ANTI-INFECTIVES

Available Alternatives

What are the commonly available Substitutes?

CYTOCOM E 150MG/300MG/600MG TABINR 108 for 3 TABLETSEFAVIRENZ 600.0 MG, ZIDOVUDINE 300.0 MG, LAMIVUDINE 150.0 MG
DUOVIR-E KITINR 117.7 for 1 KITEFAVIRENZ 600 MG, ZIDOVUDINE 300 MG, LAMIVUDINE 150 MG
VIROCOMB E 150MG/300MG/600MG KITINR 118.2 for 3 KITEFAVIRENZ 600.0 MG, ZIDOVUDINE 300.0 MG, LAMIVUDINE 150.0 MG