VIROCOMB N 150MG/300MG/200MG TAB

Overview

VIROCOMB N 150MG/300MG/200MG TAB is a Schedule H drug.

VIROCOMB N 150MG/300MG/200MG TAB is composed of: ZIDOVUDINE (300.0 MG), NEVIRAPINE (200.0 MG), LAMIVUDINE (150.0 MG)

Zidovudine is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body. Zidovudine is used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). Zidovudine is also given during pregnancy to prevent an HIV-infected woman from passing the virus to her baby. Zidovudine is not a cure for HIV or AIDS.
Nevirapine is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body. Nevirapine is used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). Nevirapine is not a cure for HIV or AIDS, and should not be used to prevent HIV. Nevirapine oral solution (liquid) is for use in adults and children as young as 15 days old. Nevirapine extended-release tablets are for use in adults and children who are at least 6 years old.

Lamivudine is an antiviral medication. It prevents the multiplication of the virus in human cells. This stops the virus from producing new viruses and clears up your infection. Lamivudine is used in the treatment of HIV infection and chronic hepatitis B virus (HBV) infection.

Usage

ZIDOVUDINE is generally used to treat: Human Immunodeficiency Virus, AIDS

NEVIRAPINE is generally used to treat: AIDS

LAMIVUDINE is generally used to treat: Hepatitis B, AIDS

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 2yrs

Q: Can it be taken during pregnancy?
A: Not enough studies to prove Risk – Ask your Doctor

Q: Is it safe to take for someone breastfeeding?
A: Check with your Doctor first

Precautions

Caution should be exercised in patients with history of bone marrow depression, low blood counts, liver, kidney diseases, obesity, any allergy, who are taking other medications, during pregnancy and breastfeeding. Avoid contact with people who have infections. Avoid sexual contact with your partner in order to avoid transmission of HIV infection. Monitor liver, kidney functions, and complete blood cell counts while taking this medication.
Caution should be exercised in patients with history of kidney disease, liver impairment, during pregnancy and breastfeeding. Patient may develop with increased risk of liver damage, serious life threatening allergic reactions, if it is so consult with your doctor. It may affect the effectiveness of oral contraceptives; consult with your doctor for other methods to prevent pregnancy while taking this medication. It may lead to redistribution/accumulation of body fat in many parts of body. Avoid drinking alcohol. It may increase your risk of liver damage.
Caution should be exercised in patients with history of hepatitis B, kidney disease, pancreas disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.  It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication. Avoid alcohol consumption. It should not be used in children less than 2 years old. It may affect blood sugar level; monitor sugar level regularly while taking this medication. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.

Symptoms of Overdosage

NEVIRAPINE over-dosage can result in: Difficulty Breathing
LAMIVUDINE over-dosage can result in: Difficulty Breathing

Common Side-Effects

ZIDOVUDINE : Nausea, Head Headache, Vomit, Difficulty Sleeping, Loss Of Appetite
NEVIRAPINE : Skin Rash, Hives, Black (tar) Colored Stools, Chills, Cough, Dark Colored (brown) Urine, Fever, Fatigue (tiredness), Weakness (generalized), Lower Back Pain, Nausea, Vomit, Pain With Urination, Throat Soreness, Loss Of Appetite
LAMIVUDINE : Nausea, Vomit, Loose Motion, Dizziness, Head Headache, Fatigue (tiredness)

Serious Side-Effects

ZIDOVUDINE : Guillan-Barre Syndrome, Goiter, Depression, Fever, Chills, Cough, Difficulty Breathing, Irregular Heartbeat, Anxiety, Confusion, Easy Bruising
LAMIVUDINE : Mood Swings, Nausea, Vomit, Abdomen Pain, Dark Colored (brown) Urine, Eyes Yellow Eyes

Rare Side-Effects

ZIDOVUDINE : Skin Rash, Dizziness, Face Swelling, Body Itching
NEVIRAPINE : Abdomen Pain, Hands Numbness, Drowsiness
LAMIVUDINE : Rapid Breathing, Drowsiness, Hands Numbness

Disease Interactions

LAMIVUDINE can interfere with: Hyperlipidemia, Pancreatitis, Alcoholism, Acute Renal Failure

Technical Classification

ZIDOVUDINE is categorized as: NNRTIS / ANTIVIRAL AGENTS / ANTI-INFECTIVES
NEVIRAPINE is categorized as: NNRTIS / ANTIVIRAL AGENTS / ANTI-INFECTIVES
LAMIVUDINE is categorized as: NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS (NRTIS) / ANTIVIRAL AGENTS / ANTI-INFECTIVES

Available Alternatives

What are the commonly available Substitutes?

DUOVIR N TAB	INR 644.11 for 30 TABLETS	ZIDOVUDINE 300.0 MG, NEVIRAPINE 200.0 MG, LAMIVUDINE 150.0 MG
DUOVIR-N FC-TAB	INR 600.08 for 30 TABLETS	ZIDOVUDINE 300 MG, NEVIRAPINE 200 MG, LAMIVUDINE 150 MG
LAZID N TAB	INR 1246.15 for 60 TABLETS	ZIDOVUDINE 300.0 MG, NEVIRAPINE 200.0 MG, LAMIVUDINE 150.0 MG
VIROCOMB N 150MG/300MG/200MG TAB	INR 1214.43 for 60 TABLETS	ZIDOVUDINE 300.0 MG, NEVIRAPINE 200.0 MG, LAMIVUDINE 150.0 MG
ZIDOLAM N N 150MG/300MG/200MG TAB	INR 654.2 for 30 TABLETS	ZIDOVUDINE 300.0 MG, NEVIRAPINE 200.0 MG, LAMIVUDINE 150.0 MG
ZIDOVEX LN 150MG/300MG/200MG TAB	INR 675 for 30 TABLETS	ZIDOVUDINE 300.0 MG, NEVIRAPINE 200.0 MG, LAMIVUDINE 150.0 MG