VIROLIS E 30MG/150MG/600MG TAB

Overview

VIROLIS E 30MG/150MG/600MG TAB is a Schedule H drug.

VIROLIS E 30MG/150MG/600MG TAB is composed of: EFAVIRENZ (600.0 MG), LAMIVUDINE (150.0 MG), STAVUDINE (30.0 MG)

Efavirenz is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body. Efavirenz is used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). Efavirenz is for adults and children who are at least 3 months old and weigh at least 8 pounds. Efavirenz is not a cure for HIV or AIDS.

Lamivudine is an antiviral medication. It prevents the multiplication of the virus in human cells. This stops the virus from producing new viruses and clears up your infection. Lamivudine is used in the treatment of HIV infection and chronic hepatitis B virus (HBV) infection.

Stavudine is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body. Stavudine is used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS).

Usage

EFAVIRENZ is generally used to treat: AIDS

LAMIVUDINE is generally used to treat: Hepatitis B, AIDS

STAVUDINE is generally used to treat: AIDS

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Check with your Doctor first

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 3month

Q: Can it be taken during pregnancy?
A: Studies indicate Risk – Doctor advice is must

How Do I Take It?

VIROLIS E 30MG/150MG/600MG TAB is generally taken Before Food.

Precautions

Efavirenz must be given in combination with other antiviral medications and it should not be used alone. Your disease may become resistant to efavirenz if you do not take it in combination with other HIV medicines your doctor has prescribed. Take efavirenz on an empty stomach at bedtime. To make swallowing easier, you may open an efavirenz capsule and sprinkle the medicine into a spoonful of applesauce, yogurt, or grape jelly. You may also mix the medicine with infant formula if you are giving the medicine to a baby. Swallow the mixture right away. Do not save it for later use. After taking efavirenz using the sprinkle method, do not eat for the next 2 hours. Efavirenz mixed with infant formula should be given to the baby right away. But do not feed the baby any more formula for at least 2 hours afterward. Efavirenz comes with instructions for mixing the capsule contents with soft food or infant formula. Follow these directions carefully. Do not crush, chew, or break an efavirenz tablet. Swallow it whole with liquid. Drinking alcohol can increase certain side effects of efavirenz. Taking this medication will not prevent you from passing HIV to other people. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.
Caution should be exercised in patients with history of hepatitis B, kidney disease, pancreas disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.  It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication. Avoid alcohol consumption. It should not be used in children less than 2 years old. It may affect blood sugar level; monitor sugar level regularly while taking this medication. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.
Caution should be exercised in patients with history of liver or kidney disease, sugar, elderly, during pregnancy and breastfeeding. Monitor patients for development of peripheral neuropathy. Redistribution/accumulation of body fat including central obesity may occur. Avoid excess dosage. Avoid drinking alcohol. It may increase your risk of pancreas or liver damage.

Symptoms of Overdosage

EFAVIRENZ over-dosage can result in: Difficulty Breathing
LAMIVUDINE over-dosage can result in: Difficulty Breathing

Common Side-Effects

EFAVIRENZ : Depression, Skin Rash, Body Itching, Blood Or Red Colored Urine, Pain With Urination, Lower Back Pain
LAMIVUDINE : Nausea, Vomit, Loose Motion, Dizziness, Head Headache, Fatigue (tiredness)
STAVUDINE : Diarrhoea, Head Headache

Serious Side-Effects

LAMIVUDINE : Mood Swings, Nausea, Vomit, Abdomen Pain, Dark Colored (brown) Urine, Eyes Yellow Eyes
STAVUDINE : Guillan-Barre Syndrome, Paralysis, Weight Loss (unintentional), Fatigue (tiredness), Fever, Chills, Difficulty Breathing, Cough, Restless Or Irritability, Nervousness, Irregular Heartbeat, Slurred Speech

Rare Side-Effects

EFAVIRENZ : Hives, Abdomen Pain, Confusion, Seizures (uncontrollable Jerking Of Limbs), Cough, Dark Colored (brown) Urine, Fainting, Fever, Chills, Head Headache, Loss Of Appetite, Nausea, Vomit
LAMIVUDINE : Rapid Breathing, Drowsiness, Hands Numbness
STAVUDINE : Skin Rash, Face Swelling, Body Itching, Dizziness

Disease Interactions

STAVUDINE can interfere with: Bone Marrow Suppression, Alcoholism, Acute Liver Failure, Pancreatitis, Hyperlipidemia, Peripheral Neuropathy, Acute Renal Failure

Technical Classification

EFAVIRENZ is categorized as: NNRTIS / ANTIVIRAL AGENTS / ANTI-INFECTIVES
LAMIVUDINE is categorized as: NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS (NRTIS) / ANTIVIRAL AGENTS / ANTI-INFECTIVES
STAVUDINE is categorized as: NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS (NRTIS) / ANTIVIRAL AGENTS / ANTI-INFECTIVES

Available Alternatives

What are the commonly available Substitutes?

EMDUO E 40MG/150MG/600MG KIT	INR 98.6 for 3 KIT	EFAVIRENZ 600.0 MG, LAMIVUDINE 150.0 MG, STAVUDINE 40.0 MG
VIROLIS E 30MG/150MG/600MG TAB	INR 99.95 for 3 TABLETS	EFAVIRENZ 600.0 MG, LAMIVUDINE 150.0 MG, STAVUDINE 30.0 MG