XPLOCEF INJ

Overview

XPLOCEF INJ is a Schedule H1 antibiotic.

XPLOCEF INJ is composed of: CEFTRIAXONE (3.0 GM), VANCOMYCIN ( )

Ceftriaxone is a cephalosporin antibiotic. It works by fighting bacteria in your body. Ceftriaxone is used to treat many kinds of bacterial infections, including severe or life-threatening forms such as meningitis. Ceftriaxone is also used to prevent infection in people having certain types of surgery.
Vancomycin is an antibiotic. When taken by mouth it fights bacteria in the intestines.Vancomycin is used to treat an infection of the intestines caused by Clostridium difficile, which can cause watery or bloody diarrhea. It is also used to treat staph infections that can cause inflammation of the colon and small intestines.It kills bacteria by preventing them from forming the bacterial protective covering which is needed for them to survive.

Usage

CEFTRIAXONE is generally used to treat: Meningitis, Bacterial Infection

VANCOMYCIN is generally used to treat: Clostridium Difficile Infection, Staph Infections, Bacterial Infection, Colitis
VANCOMYCIN can address symptoms like: Abdomen Pain, Abdomen Stomach Cramps, Loss Of Appetite, Nausea, Vomit, Fever, Bloody Or Red Colored Stools

Frequently Asked Questions

Q: Is it safe on my liver?
A: Check with your Doctor first

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 12month

Q: Can it be taken during pregnancy?
A: Not enough studies to prove Risk – Ask your Doctor

Q: Is it safe to take for someone breastfeeding?
A: Not Safe

Precautions

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to. Caution should be exercised in patients with history of penicillin allergy; severe renal impairment; pregnancy and lactation; problem with digestive system, especially colitis (inflammation of the large intestine), malnutrition (you do not eat or cannot digest the nutrients needed for good health), super infection. Be sure for the full course of treatment. If you do not, the medicine may not clear up your infection completely.

• Oral vancomycin works only in the intestines and will not treat infections in other parts of the body.
• You should not take this medication if you are allergic to vancomycin.
• Take vancomycin exactly as prescribed by your doctor. Follow all directions on your prescription label.
• Do not take this medicine in larger or smaller amounts or for longer than recommended.Taking more of this medicine will not make it more effective, and may cause serious or life-threatening side effects.
• Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared.
• If you use this medication long-term, you may need frequent medical tests at your doctor’s office.
• Shake the oral suspension (liquid) well just before you measure a dose.
• Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup.
• Do not take extra medicine to make up the missed dose.
• Do not drive because you may feel sleepy or dizzy while being treated with vancomycin.
• Do not start or continue the vancomycin if you have a kidney problem or hearing difficulties.

Symptoms of Overdosage

CEFTRIAXONE over-dosage can result in: Seizures (uncontrollable Jerking Of Limbs), Difficulty Breathing

Common Side-Effects

CEFTRIAXONE : Black (tar) Colored Stools, Chest Pain, Chills, Cough, Fever, Throat Soreness, Fatigue (tiredness), Weakness (generalized), Loose Motion
VANCOMYCIN : Skin Rash, Itchy Skin, Hypokalemia, Blood Pressure, Low, Nausea, Abdomen Pain, Abdomen Bloating Or Fullness, Fever, Fatigue (tiredness), Vomit, Decreased Urination, Drowsiness, Weakness (generalized), Head Headache, Increased Passing Gas, Redness, Lightheadedness, Abdomen Upset Stomach, Difficulty Breathing

Serious Side-Effects

CEFTRIAXONE : Abdomen Pain, Nausea, Vomit, Dark Colored (brown) Urine, Frequent Urination, Eyes Yellow Eyes, Mood Swings, Seizures (uncontrollable Jerking Of Limbs)
VANCOMYCIN : Hearing Loss, Seizure, Muscle Pain, Palpitation, Vertigo, Blood Or Red Colored Urine, Dry Mouth, Pain With Urination, Frequent Urge To Urinate, Increased Thirst, Irregular Heartbeat, Loss Of Appetite, Lower Back Pain, Mood Swings, Hands Tingling, Feet Tingling, Weight Gain, Weight Loss (unintentional), Unusual Taste In Mouth, Ringing In Ears, Hearing Loss, Easy Bleeding

Rare Side-Effects

CEFTRIAXONE : Skin Rash, Dizziness, Difficulty Breathing, Body Itching, Face Swelling
VANCOMYCIN : Hives, Body Discoloration

Disease Interactions

VANCOMYCIN can interfere with: Hearing Loss, Tinnitus, Acute Renal Failure, Colitis, Neutropenia, Thrombocytopenia, Ulcerative Colitis

Technical Classification

CEFTRIAXONE is categorized as: ANTIBIOTICS/ANTINEOPLASTICS / ANTINEOPLASTICS
VANCOMYCIN is categorized as: GLYCOPEPTIDE ANTIBIOTICS / ANTI-INFECTIVES

Available Alternatives

What are the commonly available Substitutes?

CEFIRONE V 1000MG/500MG INJ	INR 390 for 1 INJECTION	CEFTRIAXONE 1000.0 MG, VANCOMYCIN 500.0 MG
VANCO PLUS 1000MG/500MG INJ	INR 428 for 10 ML INJECTION	CEFTRIAXONE 1000.0 MG, VANCOMYCIN 500.0 MG
VANCO PLUS 2000MG/1000MG INJ	INR 845 for 1 INJECTION	CEFTRIAXONE 2000.0 MG, VANCOMYCIN 1000.0 MG
XL V 1000MG/500MG INJ	INR 360 for 1 INJECTION	CEFTRIAXONE 1000.0 MG, VANCOMYCIN 500.0 MG
XL V 2000MG/1000MG INJ	INR 672.33 for 1 INJECTION	CEFTRIAXONE 2000.0 MG, VANCOMYCIN 1000.0 MG
XPLOCEF 2000MG/1000MG INJ	INR 717.13 for 20 ML INJECTION	CEFTRIAXONE 2000.0 MG, VANCOMYCIN 1000.0 MG
XPLOCEF INJ	INR 700 for 10 ML INJECTION	CEFTRIAXONE 3.0 GM, VANCOMYCIN