ZAPDIC 50MG/325MG/2MG TAB

Overview

ZAPDIC 50MG/325MG/2MG TAB is a Schedule H drug.

ZAPDIC 50MG/325MG/2MG TAB is composed of: PARACETAMOL (325.0 MG), DICLOFENAC SODIUM (50.0 MG), TIZANIDINE (2.0 MG)

Paracetamol is a pain reliever and a fever reducer. The exact mechanism of action of is not known. Paracetamol is used to treat many conditions such as a headache, muscle aches, arthritis, backache, toothaches, colds, and fevers. It relieves pain in mild arthritis but has no effect on the underlying inflammation and swelling of the joint.

Diclofenac Sodium is an anti-inflammatory painkiller. This non-steroidal drug is used to alleviate symptoms of arthritis such as inflammation, pain, fever and swollen joints. It is used in the treatment of conditions such as rheumatoid arthritis, osteoarthritis, ankylosing spondylosis and severe menstrual pain. Diclofenac Sodium works by obstructing the production of cyclooxygenase, which synthesizes the compound called prostaglandin. This compound is responsible for symptoms of arthritis such as pain, swelling and inflammation. .
Tizanidine is a short-acting muscle relaxer. It works by blocking nerve impulses (pain sensations) that are sent to your brain. Tizanidine is used to treat spasticity by temporarily relaxing muscle tone.

Usage

PARACETAMOL is generally used to treat: Arthritis
PARACETAMOL can address symptoms like: Head Headache, Back Pain, Cold, Fever

DICLOFENAC SODIUM is generally used to treat: Rheumatoid Arthritis, Osteoarthritis, Ankylosing Spondylitis, Menstrual Cramp, Pain
DICLOFENAC SODIUM can address symptoms like: Fever, Knees Joint Pain

TIZANIDINE is generally used to treat: Spasticity

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 1month

Q: Can it be taken during pregnancy?
A: Not enough studies to prove Risk – Ask your Doctor

Q: Is it safe to take for someone breastfeeding?
A: Not Safe

How Do I Take It?

ZAPDIC 50MG/325MG/2MG TAB is generally taken After Food.

Precautions

Caution should be exercised in patients with history of asthma, bleeding problems, growths in the nose, heart, kidney or liver disease, liver inflammation, high blood pressure, chickenpox, anxiety, trouble in sleeping, ulcers, stomach problems, stroke, Kawasaki syndrome, any allergy, who are taking other medications, during pregnancy and breastfeeding. Avoid alcohol consumption. It should not be used in children with infections such as flu, chickenpox or viral infections. Avoid large amount of caffeinated beverages while taking this medication. It may reduce platelet counts; avoid injury or bruising.

• Pregnant women, women trying to conceive, smokers and alcoholics should avoid taking Diclofenac Sodium, since it can have harmful effects.
• Avoid taking aspirin or other NSAIDs while you are taking this medicine.
• If you use diclofenac long-term, you may need frequent medical tests.
• Take Diclofenac sodium on an empty stomach, at least 1 hour before or 2 hours after a meal.
• Do not crush, chew, or break an extended-release tablet or delayed-release tablet. Swallow it whole.
• Dissolve diclofenac sodium powder in to 2 ounces of water. Do not use any other type of liquid. Stir this mixture and drink all of it right away. It works best if you take it on an empty stomach.
• It is not known whether diclofenac passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.
• Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft).

Caution should be exercised in patients with history of prolonged QT interval, liver or kidney disease, children, elderly, pregnancy and breastfeeding. Monitor LFT(Liver Function test) regularly. Stop treatment if liver enzymes are raised persistently greater than 3 times upper limit of normal range. Avoid abrupt withdrawal of therapy. It may make you drowsy. Do not drive a car or operate machinery while taking this medication.

Symptoms of Overdosage

PARACETAMOL over-dosage can result in: Loss Of Appetite, Nausea, Vomit, Abdomen Pain, Weakness (generalized), Upper Abdomen Pain, Dark Colored (brown) Urine, Eyes Yellow Eyes
DICLOFENAC SODIUM over-dosage can result in: Abdomen Pain, Vomit, Drowsiness, Difficulty Breathing, Seizures (uncontrollable Jerking Of Limbs)
TIZANIDINE over-dosage can result in: Weakness (generalized), Drowsiness, Confusion, Slow Heart Rate (pulse), Slow Or Irregular Breathing, Lightheadedness, Fainting

Common Side-Effects

DICLOFENAC SODIUM : Skin Rash, Itchy Skin, Indigestion, Abdomen Bloating Or Fullness, Abdomen Burn, Abdomen Pain, Belching, Black (tar) Colored Stools, Cloudy Urine With Strong Odor, Constipation, Loose Motion, Dizziness, Head Headache, Loss Of Appetite, Nausea, Vomit, Pale Skin, Fatigue (tiredness), Weakness (generalized), Weight Loss (unintentional)
TIZANIDINE : Dry Mouth, Constipation, Fatigue (tiredness)

Serious Side-Effects

TIZANIDINE : Irregular Heartbeat, Hallucinations, Eyes Blurred Vision

Rare Side-Effects

PARACETAMOL : Skin Rash, Dizziness, Difficulty Breathing, Face Swelling, Body Itching
TIZANIDINE : Skin Rash, Difficulty Breathing, Face Swelling, Body Itching

Disease Interactions

TIZANIDINE can interfere with: Acute Liver Failure, Hypotension, Acute Renal Failure, Psychosis

Technical Classification

PARACETAMOL is categorized as: MISCELLANEOUS ANALGESICS / ANALGESICS / CENTRAL NERVOUS SYSTEM AGENTS
DICLOFENAC SODIUM is categorized as: NONSTEROIDAL ANTI-INFLAMMATORY AGENTS / ANALGESICS / CENTRAL NERVOUS SYSTEM AGENTS
TIZANIDINE is categorized as: SKELETAL MUSCLE RELAXANTS / MUSCLE RELAXANTS / CENTRAL NERVOUS SYSTEM AGENTS

Available Alternatives

What are the commonly available Substitutes?

DILONA MR 50MG/325MG/2MG TAB	INR 185.5 for 10 TABLET MR	PARACETAMOL 325.0 MG, DICLOFENAC SODIUM 50.0 MG, TIZANIDINE 2.0 MG
DIPANE MR 50MG/325MG/2MG TAB	INR 11.18 for 10 TABLETS	PARACETAMOL 325.0 MG, DICLOFENAC SODIUM 50.0 MG, TIZANIDINE 2.0 MG
DOUSE MR 50MG/325MG/2MG TAB	INR 50.31 for 10 TABLET MR	PARACETAMOL 325.0 MG, DICLOFENAC SODIUM 50.0 MG, TIZANIDINE 2.0 MG
POSTURE 50MG/325MG/2MG TAB	INR 35.62 for 10 TABLETS	PARACETAMOL 325.0 MG, DICLOFENAC SODIUM 50.0 MG, TIZANIDINE 2.0 MG
TIZALUD DP 50MG/325MG/2MG TAB	INR 63.75 for 10 TABLETS	PARACETAMOL 325.0 MG, DICLOFENAC SODIUM 50.0 MG, TIZANIDINE 2.0 MG
TIZPA DP TAB	INR 42 for 10 TABLETS	PARACETAMOL 500.0 MG, DICLOFENAC SODIUM 50.0 MG, TIZANIDINE 2.0 MG
VOZOX MR 50MG/325MG/2MG TAB	INR 54 for 10 TABLET MR	PARACETAMOL 325.0 MG, DICLOFENAC SODIUM 50.0 MG, TIZANIDINE 2.0 MG
ZAPDIC 50MG/325MG/2MG TAB	INR 54.62 for 10 TABLETS	PARACETAMOL 325.0 MG, DICLOFENAC SODIUM 50.0 MG, TIZANIDINE 2.0 MG