ZAPTRA LS 12.5MG/0.25MG CAP - mTatva Health-PIE

Contents

1 Overview
2 Usage
3 Frequently Asked Questions
4 Precautions
5 Symptoms of Overdosage
6 Common Side-Effects
7 Serious Side-Effects
8 Rare Side-Effects
9 Food Interactions
10 Disease Interactions
11 Technical Classification
12 Available Alternatives
- 12.1 What are the commonly available Substitutes?
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Overview

ZAPTRA LS 12.5MG/0.25MG CAP is a Schedule X drug.

ZAPTRA LS 12.5MG/0.25MG CAP is composed of: PAROXETINE (12.5 MG), CLONAZEPAM (0.25 MG)

Paroxetine affects chemicals in the brain that may be unbalanced in people with depression, anxiety, or other disorders.The Brisdelle brand of paroxetine is used to treat hot flashes related to menopause. Brisdelle is not for treating any other conditions.It increases the amount of serotonin, a natural substance in the brain that helps maintain mental balance. This improves mood and physical symptoms in depression and relieves symptoms of panic and obsessive disorders.

Clonazepam is a benzodiazepine. It affects chemicals in the brain that may be unbalanced. Clonazepam is also a seizure medicine, also called an anti-epileptic drug. Clonazepam is used to treat certain seizure disorders (including absence seizures or Lennox-Gastaut syndrome) in adults and children. Clonazepam is also used to treat panic disorder (including agoraphobia) in adults.Clonazepam is used in the treatment of epilepsy and anxiety disorder.Clonazepam is a benzodiazepine. It works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Usage

PAROXETINE is generally used to treat: Obsessive-Compulsive Disorder, Panic Attack, Depression, Anxiety, Post Traumatic Stress Disorder (PTSD)
PAROXETINE can address symptoms like: Depressed Mood, Hot Flashes, Hyperactive Behavior, Fearful, Decreased Appetite

CLONAZEPAM is generally used to treat: Panic Disorder, Epilepsy, Seizure
CLONAZEPAM can address symptoms like: Seizures (uncontrollable Jerking Of Limbs)

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 18yrs

Q: Can it be taken during pregnancy?
A: Dangerous – Studies indicate Human-Fetal Risk

Precautions

You should not use paroxetine if you are also taking pimozide or thioridazine.
Do not use paroxetine within 14 days before or 14 days after you have used a MAO inhibitor.
Do not start or stop taking paroxetine during pregnancy without your doctor’s advice.
You should not use this medicine if you are allergic to paroxetine.Take paroxetine exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Do not crush, chew, or break an extended-release paroxetine tablet. Swallow it whole.
Do not stop using paroxetine suddenly, or you could have unpleasant withdrawal symptoms.
Do not take extra medicine to make up the missed dose.
Using an NSAID with paroxetine may cause you to bruise or bleed easily.
Paroxetine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.The addiction/dependence potential of Paroxetine is very less.

If you are taking Clonazepam for the treatment of insomnia and anxiety, it should not be used more than 4 weeks.
It may become less effective over the time.
It causes sleepiness or drowsiness. If this happens to you, do not drive or use machinery.
Avoid consuming alcohol when taking the Clonazepam, as it may cause excessive sleepiness or drowsiness.
Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Inform your doctor if you have ever been diagnosed with kidney or liver problems.
The addiction / habit-forming potential of Clonazepam is very high.
You should not use clonazepam if you have narrow-angle glaucoma or severe liver disease, or if you are allergic to Valium or a similar medicineTake clonazepam exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.Misuse of habit-forming medicine can cause addiction, overdose, or death. Selling or giving away this medicine is against the law.
Clonazepam should be used for only a short time. Do not take this medication for longer than 9 weeks without your doctor’s advice.
Swallow the tablet whole, with a full glass of water.

Symptoms of Overdosage

PAROXETINE over-dosage can result in: Irregular Heartbeat, Fainting, Dizziness, Seizures (uncontrollable Jerking Of Limbs)
CLONAZEPAM over-dosage can result in: Drowsiness, Confusion, Difficulty Breathing

Common Side-Effects

PAROXETINE : Insomnia, Skin Rash, Muscle Pain, Eyes Change In Vision, Weakness (generalized), Drowsiness, Dizziness, Loss Of Appetite, Difficulty Sleeping, Dry Mouth, Body Excessive Sweating, Agitation, Chest Pain, Chills, Confusion, Difficulty Breathing, Runny Nose, Abdomen Discomfort, Slow Or Irregular Breathing, Unusual Taste In Mouth, Eyes Itching, Eyes Pain, Eyes Redness, Eyes Swelling, Memory Problems, Irregular Menstrual Periods, Difficulty Concentrating, Eyes Watery Eyes, Loss Of Voice, Erectile Dysfunction
CLONAZEPAM : Hives, Ataxia, Dizziness, Depression, Constipation, Difficulty Swallowing, Throat Soreness, Heavy Menstrual Bleeding, Eyes Pain, Drowsiness, Inappropriate Behavior, Slurred Speech, Dry Mouth, Fatigue (tiredness), Restless Or Irritability, Head Headache, Loss Of Coordination

Serious Side-Effects

PAROXETINE : Heartburn, Seizure, Vision Problems, Belching, Decreased Appetite, Increased Passing Gas, Difficulty Urinating, Abdomen Pain, Inappropriate Behavior, Restless Or Irritability, Black (tar) Colored Stools, Bloody Or Red Colored Vomit
CLONAZEPAM : Dizziness, Headache, Breathlessness, Panic Attack, Body Pain, Chills, Cough, Difficulty Breathing, Restless Or Irritability, Loss Of Appetite, Runny Nose, Nasal Congestion, Sneezing, Throat Soreness, Difficulty Sleeping, Difficulty Concentrating, Weakness (generalized)

Rare Side-Effects

PAROXETINE : Serotonin Syndrome, Eyes Enlarged (dilated) Pupils, Body Loss Of Movement, Difficulty Talking, Fever, Eyes Sensitive To Light, Loss Of Coordination, Loose Motion, Hallucinations, Rapid Heart Rate (pulse)
CLONAZEPAM : Night Terrors, Itchy Skin, Skin Rash, Anxiety, Chest Pain, Dry Mouth, Hyperventilation, MEMORY LOSS, Nosebleeds, Heartburn, Indigestion, Toothache, Chest Pain, Body Discoloration, Eyes Change In Vision, Irregular Heartbeat, Cough

Food Interactions

No content

Disease Interactions

CLONAZEPAM can interfere with: Seizure, Obesity, Depression

Technical Classification

PAROXETINE is categorized as: SELECTIVE SEROTONIN REUPTAKE INHIBITORS / ANTIDEPRESSANTS / PSYCHOTHERAPEUTIC AGENTS
CLONAZEPAM is categorized as:

BENZODIAZEPINE ANTICONVULSANTS / ANTICONVULSANTS / CENTRAL NERVOUS SYSTEM AGENTS
BENZODIAZEPINES / ANXIOLYTICS, SEDATIVES, AND HYPNOTICS / CENTRAL NERVOUS SYSTEM AGENTS

Available Alternatives

What are the commonly available Substitutes?

CLONOTRIL P 12.5MG/0.25MG TAB	INR 107.83 for 10 TABLETS	PAROXETINE 12.5 MG, CLONAZEPAM 0.25 MG
CLONOTRIL P 25MG/0.25MG TAB	INR 131.25 for 10 TABLETS	PAROXETINE 25.0 MG, CLONAZEPAM 0.25 MG
LUPIZEP PLUS 12.5MG/0.5MG TAB	INR 115 for 10 TABLETS	PAROXETINE 12.5 MG, CLONAZEPAM 0.5 MG
LUPIZEP PLUS 25MG/0.5MG TAB	INR 140 for 10 TABLETS	PAROXETINE 25.0 MG, CLONAZEPAM 0.5 MG
PANAZEP LS 12.5MG/0.25MG TAB	INR 115 for 10 TABLETS	PAROXETINE 12.5 MG, CLONAZEPAM 0.25 MG
PANAZEP LS TAB	INR 120 for 10 TABLETS	PAROXETINE 12.5 MG, CLONAZEPAM 0.25 MG
PARI CR PLUS TAB	INR 120 for 10 TABLETS	PAROXETINE 12.5 MG, CLONAZEPAM 0.5 MG
PARI FORTE TAB	INR 160 for 10 TABLETS	PAROXETINE 25.0 MG, CLONAZEPAM 0.5 MG
PARO CR FORTE TAB	INR 142 for 10 TABLETS	PAROXETINE 25.0 MG, CLONAZEPAM 0.5 MG
PARO CR PLUS TAB	INR 110 for 10 TABLETS	PAROXETINE 25.0 MG, CLONAZEPAM 12.5 MG
PAROXTA PLUS 12.5MG/0.5MG TAB	INR 100 for 10 TABLETS	PAROXETINE 12.5 MG, CLONAZEPAM 0.5 MG
PAROXTA PLUS 25MG/0.5MG TAB	INR 132.37 for 10 TABLETS	PAROXETINE 25.0 MG, CLONAZEPAM 0.5 MG
PAROZEP TAB	INR 145 for 10 TABLETS	PAROXETINE 25.0 MG, CLONAZEPAM
PATROXTA PLUS 12.5MG TAB	INR 105 for 10 TABLETS	PAROXETINE 12.5 MG, CLONAZEPAM 0.5 MG
PATROXTA PLUS 25MG TAB	INR 139 for 10 TABLETS	PAROXETINE 25.0 MG, CLONAZEPAM 0.5 MG
PAXI CR FORTE 25MG/0.5MG TAB	INR 145 for 10 TABLETS	PAROXETINE 25.0 MG, CLONAZEPAM 0.5 MG
PAXONIL LS 12.5MG/0.25MG TAB	INR 124 for 10 TABLETS	PAROXETINE 12.5 MG, CLONAZEPAM 0.25 MG
PAXONIL PLUS 12.5MG/0.5MG TAB	INR 121.9 for 10 TABLETS	PAROXETINE 12.5 MG, CLONAZEPAM 0.5 MG
PAXONIL PLUS 25MG/0.5MG TAB	INR 160 for 10 TABLETS	PAROXETINE 25.0 MG, CLONAZEPAM 0.5 MG
PEXEP PLUS 12.5MG/0/5MG CAP	INR 135 for 10 CAPSULES	PAROXETINE 12.5 MG, CLONAZEPAM 0.5 MG
PEXEP PLUS 25MG CAP	INR 181 for 10 CAPSULES	PAROXETINE 25 MG, CLONAZEPAM 0.5 MG
XET CR PLUS 12.5MG/0.25MG CAP	INR 137.6 for 10 CAPSULES	PAROXETINE 12.5 MG, CLONAZEPAM 0.25 MG
XET CR PLUS 25 MG/0.25 MG CAPSULE	INR 137.6 for 10 CAPSULES	PAROXETINE 12.5 MG, CLONAZEPAM 0.25 MG
XET CR PLUS 25MG/0.25MG CAP	INR 174.8 for 10 CAPSULES	PAROXETINE 25.0 MG, CLONAZEPAM 0.25 MG
ZAPTRA 12.5MG TAB	INR 135 for 10 TABLETS	PAROXETINE 12.5 MG, CLONAZEPAM 0.5 MG
ZAPTRA 12.5MG/0.25MG CAP	INR 135 for 10 CAPSULES	PAROXETINE 12.5 MG, CLONAZEPAM 0.25 MG
ZAPTRA 25MG TAB	INR 181 for 10 TABLETS	PAROXETINE 25 MG, CLONAZEPAM 0.25 MG
ZAPTRA 25MG/0.25MG CAP	INR 181 for 10 CAPSULES	PAROXETINE 25.0 MG, CLONAZEPAM 0.25 MG
ZAPTRA LS 12.5MG/0.25MG CAP	INR 109 for 10 CAPSULES	PAROXETINE 12.5 MG, CLONAZEPAM 0.25 MG
ZAPTRA LS CAP	INR 135 for 10 CAPSULES	PAROXETINE 12.5 MG, CLONAZEPAM 0.25 MG