ZERODOL-MR TAB

Overview

ZERODOL-MR TAB is a Schedule H drug.

ZERODOL-MR TAB is composed of: ACECLOFENAC (100 MG), TIZANIDINE (2 MG)

Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) with analgesic properties. Aceclofenac potently inhibits the cyclo-oxygenase enzyme (COX) that is involved in the synthesis of prostaglandins, which are inflammatory mediators that cause pain, swelling, inflammation, and fever.  It is orally administered for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.

Tizanidine is a short-acting muscle relaxer. It works by blocking nerve impulses (pain sensations) that are sent to your brain. Tizanidine is used to treat spasticity by temporarily relaxing muscle tone.

Usage

ACECLOFENAC is generally used to treat: Osteoarthritis, Rheumatoid Arthritis, Ankylosing Spondylitis

TIZANIDINE is generally used to treat: Spasticity

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Ask your doctor

Q: Can it be taken during pregnancy?
A: Not enough studies to prove Risk – Ask your Doctor

Q: Is it safe to take for someone breastfeeding?
A: Not Safe

How Do I Take It?

ZERODOL-MR TAB is generally taken With Food.

Precautions for ZERODOL-MR TAB and its Constituents

• if the stools in black or blood consult your doctor.
• not fully safe to take while pregnant and breastfeeding.
• swallow the tablet whole with aglass of water do not crush or chew the tablets.

Caution should be exercised in patients with history of prolonged QT interval, liver or kidney disease, children, elderly, pregnancy and breastfeeding. Monitor LFT(Liver Function test) regularly. Stop treatment if liver enzymes are raised persistently greater than 3 times upper limit of normal range. Avoid abrupt withdrawal of therapy. It may make you drowsy. Do not drive a car or operate machinery while taking this medication.

Symptoms of Overdosage

ACECLOFENAC over-dosage can result in: Abdomen Pain, Nausea, Head Headache, Dizziness, Drowsiness
TIZANIDINE over-dosage can result in: Weakness (generalized), Drowsiness, Confusion, Slow Heart Rate (pulse), Slow Or Irregular Breathing, Lightheadedness, Fainting

Common Side-Effects

ACECLOFENAC : Osteoarthritis, Rheumatoid Arthritis, Ankylosing Spondylitis, Head Headache, Nausea, Vomit, Drowsiness, Dizziness
TIZANIDINE : Dry Mouth, Constipation, Fatigue (tiredness)

Serious Side-Effects

ACECLOFENAC : Black (tar) Colored Stools, Bloody Or Red Colored Stools, Wheezing
TIZANIDINE : Irregular Heartbeat, Hallucinations, Eyes Blurred Vision

Rare Side-Effects

TIZANIDINE : Skin Rash, Difficulty Breathing, Face Swelling, Body Itching

Disease Interactions

TIZANIDINE can interfere with: Acute Liver Failure, Hypotension, Acute Renal Failure, Psychosis

Technical Classification

ACECLOFENAC is categorized as: NONSTEROIDAL ANTI-INFLAMMATORY AGENTS / ANALGESICS / CENTRAL NERVOUS SYSTEM AGENTS
TIZANIDINE is categorized as: SKELETAL MUSCLE RELAXANTS / MUSCLE RELAXANTS / CENTRAL NERVOUS SYSTEM AGENTS

Prescription Statistics

Following information is taken from treatment plans advised by our doctors. This is Only for informational purpose and you must seek doctor’s advice if you are not well.

How Frequently is it taken?

2 Times Daily	59%
2 Times Daily (1-0-1)	29%
SOS	8%

Directions with respect to food?

After Food

100%

How long was it prescribed?

5 Days	49%
3 Days	26%
7 Days	20%

What is the break-up across patient age-group?

Below 5yrs	1%
12 to 18yrs	2%
18 to 35yrs	36%
35 to 50yrs	27%
50 to 60yrs	11%
60 to 70yrs	16%
70yrs and above	8%

What is the gender-breakup across patients?

Females

53%

What kind of doctors prescribe this medicine?

Orthopaedist	54%
ENT	35%
Physician	9%
Neurologist	1%

Most common Medicines advised along-side?

PAN 40MG TAB	18%
ARACHITOL 6L AMP	13%
A TO Z TAB	12%
VOLINI GEL	12%
UBICAR TAB	12%
REJUNURON FORTE INJ	11%

Available Alternatives for ZERODOL-MR TAB

What are the commonly available Substitutes?

ACCETIZ 100MG/2MG TAB	INR 40 for 10 TABLETS	ACECLOFENAC 100.0 MG, TIZANIDINE 2.0 MG
TIZANAC AC 100MG/2MG TAB	INR 59.93 for 10 TABLETS	ACECLOFENAC 100.0 MG, TIZANIDINE 2.0 MG
ZERODOL-MR TAB	INR 65 for 10 TABLETS	ACECLOFENAC 100 MG, TIZANIDINE 2 MG

What are the other drugs with similar Ingredients?

ACCETIZ P 100MG/500MG/2MG TAB	INR 57.1 for 10 TABLETS	PARACETAMOL 500.0 MG, ACECLOFENAC 100.0 MG, TIZANIDINE 2.0 MG
ACENOVA TAB MR	INR 50 for 10 TABLET MR	ACECLOFENAC , PARACETAMOL , TIZANIDINE
ACICLOFLEX 100MG/500MG/2MG TAB MR	INR 53 for 10 TABLET MR	PARACETAMOL 500.0 MG, ACECLOFENAC 100.0 MG, TIZANIDINE 2.0 MG
ACOTA MR TAB	INR 39.95 for 10 TABLET MR	ACECLOFENAC , PARACETAMOL , TIZANIDINE
ASFLAM TAB	INR 48.61 for 10 TABLETS	ACECLOFENAC , TIZANIDINE , SERRATIOPEPTIDASE , PARACETAMOL
KINECTINE MR TAB	INR 55.95 for 10 TABLET MR	PARACETAMOL 500.0 MG, ACECLOFENAC 100.0 MG, TIZANIDINE 2.0 MG
MOVON-MR 100MG/500MG/2MG TAB	INR 65 for 10 TABLETS	PARACETAMOL 500.0 MG, ACECLOFENAC 100.0 MG, TIZANIDINE 2.0 MG
VALDONE MR 100MG/500MG/2MG TAB	INR 42 for 10 TABLET MR	PARACETAMOL 500.0 MG, ACECLOFENAC 100.0 MG, TIZANIDINE 2.0 MG