ZINSTO 2%/0.01% CRM

Overview

ZINSTO 2%/0.01% CRM is a Schedule H drug.

ZINSTO 2%/0.01% CRM is composed of: FLUOCINOLONE (2.0 %), MICONAZOLE (0.01 %)

Fluocinolone is a steroid medicine. It prevents the release of substances in the body that cause inflammation. Fluocinolone ophthalmic (for the eye) implant is used to treat inflammation within the eye that is caused by disease or infection. The implant slowly releases fluocinolone into the eye over a period of approximately 30 months. Fluocinolone is not an antibiotic and will not treat an eye infection.

Miconazole is an antifungal medicine that fights infections caused by fungus.Miconazole buccal is a pill placed between your check and gum to treat candida (yeast) infections inside the mouth.
It kills fungi by destroying the fungal cell membrane. This treats your infection.

Usage

FLUOCINOLONE is generally used to treat: Eyelid Inflammation

MICONAZOLE is generally used to treat: Fungal Infection, Yeast Infection, Athlete’s Foot, Jock Itch, Vaginal Candidiasis

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 12yrs

Q: Can it be taken during pregnancy?
A: Not enough studies to prove Risk – Ask your Doctor

Q: Is it safe to take for someone breastfeeding?
A: Not Safe

Precautions


Do not use other eye medications unless your doctor tells you to. Ask your doctor before wearing contact lenses after receiving the fluocinolone ophthalmic implant. This medicine may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.


  • Follow all directions on your medicine label and package.You should not use this medicine if you are allergic to miconazole (Monistat, Vusion, and others) or if you are allergic to milk proteins.
  • Do not use this medicine in larger or smaller amounts or for longer than recommended.
  • The usual dose of this medicine is one tablet each morning for 14 days in a row.
  • Brush your teeth before putting in a buccal tablet.
  • Make sure your hands are dry before handling the tablet.
  • Do not chew or swallow the buccal tablet. Leave it in place until the next morning.
  • Avoid touching or pressing the tablet while it is in place.
  • You may eat and drink normally while the tablet is in place, but avoid chewing gum.If any pieces of the tablet remain in your mouth the next morning, rinse your mouth with water before using a new tablet.
  • Avoid wearing an upper denture if it gets in the way of the buccal tablet.Do not skip any doses and finish the full course of treatment even if you feel better.
  • Avoid contact with your eyes.

Symptoms of Overdosage

FLUOCINOLONE over-dosage can result in: Eyes Blurred Vision

Common Side-Effects

FLUOCINOLONE : Glaucoma, Eyes Blurred Vision
MICONAZOLE : Pain, Diarrhoea, Itchy Skin, Toothache, Abdomen Pain, Loss Of Appetite, Weakness (generalized), Upper Abdomen Pain, Head Headache, Nausea, Dry Mouth, Decreased Taste, Gums Redness, Body Pain, Fever, Chills, Nasal Congestion, Pale Skin, Runny Nose, Sneezing, Throat Soreness, Fatigue (tiredness)

Serious Side-Effects

FLUOCINOLONE : Eyes Blindness, Eyes Blurred Vision, Eyes Itching, Eyes Burn, Eyes Dry Eyes, Eyes Pain, Eyes Swelling, Eyes Redness
MICONAZOLE : Difficulty Breathing, Pain With Urination, Tongue Soreness

Rare Side-Effects

MICONAZOLE : Mouth Ulcer, Black (tar) Colored Stools, Shortness Of Breath, Mouth Soreness

Disease Interactions

MICONAZOLE can interfere with: Acute Liver Failure, Hyperlipidemia

Technical Classification

FLUOCINOLONE is categorized as: OPHTHALMIC STEROIDS / OPHTHALMIC PREPARATIONS / TOPICAL AGENTS
MICONAZOLE is categorized as: AZOLE ANTIFUNGALS / ANTIFUNGALS / ANTI-INFECTIVES

Available Alternatives

What are the commonly available Substitutes?

ALMIZOL F CRMINR 13.12 for 15 GM CREAMMICONAZOLE , FLUOCINOLONE
CONIDERM F 0.01%/2% CRMINR 75 for 15 GM CREAMMICONAZOLE 2.0 %, FLUOCINOLONE 0.01 %
DERMOLAM CRMINR 45.9 for 15 GM CREAMMICONAZOLE , FLUOCINOLONE
FUNGIDERM F 0.01%/2% CRMINR 50 for 15 GM CREAMMICONAZOLE 2.0 %, FLUOCINOLONE 0.01 %
FUNGITOP F GELINR 30 for 15 GM GELMICONAZOLE 2.0 %, FLUOCINOLONE 0.01 %
FUNGITOP F OINTINR 30 for 15 GM OINTMENTMICONAZOLE 2.0 %, FLUOCINOLONE 0.01 %
GIPADERM CRMINR 19.35 for 5 GM CREAMFLUOCINOLONE , MICONAZOLE
MICOGEL F CRMINR 43 for 15 GM CREAMMICONAZOLE 2.0 %, FLUOCINOLONE 0.01 %
MICOGEL F OINTINR 47 for 15 GM OINTMENTMICONAZOLE 2.0 %W/W, FLUOCINOLONE 0.01 %W/W
MICOMON F CRMINR 14.42 for 15 GM CREAMMICONAZOLE 2.0 %, FLUOCINOLONE 0.01 %
MYCOZOLE F CRMINR 10.11 for 15 GM CREAMMICONAZOLE 2.0 %W/W, FLUOCINOLONE 0.01 %W/W
REXGARD F 0.1%/2% OINTINR 16.15 for 15 GM OINTMENTMICONAZOLE 2.0 %, FLUOCINOLONE 0.1 %
RIVIZOLE F 0.01%/2% OINTINR 13.75 for 15 GM OINTMENTMICONAZOLE 2.0 %, FLUOCINOLONE 0.01 %
THREE DERM CRMINR 11.31 for 5 GM CREAMMICONAZOLE , FLUOCINOLONE
ZINSTO 2%/0.01% CRMINR 49 for 15 GM CREAMFLUOCINOLONE 2.0 %, MICONAZOLE 0.01 %
ZOLE F 0.01% W/V/2% W/V LTNINR 42 for 15 ML LOTIONMICONAZOLE 2.0 %W/V, FLUOCINOLONE 0.01 %W/V
ZOLE F 0.01% W/W/2% W/W OINTINR 62.5 for 15 GM OINTMENTMICONAZOLE 2.0 %W/W, FLUOCINOLONE 0.01 %W/W
ZOLE F LOTIONINR 42 for 15 ML LOTIONMICONAZOLE 2 %W/V, FLUOCINOLONE 0.01 %W/V
ZOLE F NEO CRMINR 33.5 for MICONAZOLE 2 %W/W, FLUOCINOLONE 0.01 %W/W
ZOLE F OINTINR 62.5 for 15 GRAM OINTMENTMICONAZOLE 2 %W/W, FLUOCINOLONE 0.01 %W/W

What are the other drugs with similar Ingredients?

FLUCREME NM OINTINR 54 for 10 GM OINTMENTMICONAZOLE 2.0 %W/W, NEOMYCIN 0.5 %W/W, FLUOCINOLONE 0.025 %W/W
MICONA F CRMINR 40.83 for 15 GM CREAMMICONAZOLE 2.0 %W/W, NEOMYCIN 0.5 %W/W, FLUOCINOLONE 0.025 %W/W