ZYLOPRED 0.3% W/V/0.5% W/V EYE DPS

Contents

1 Overview
2 Usage
3 Frequently Asked Questions
4 Precautions
5 Common Side-Effects
6 Serious Side-Effects
7 Rare Side-Effects
8 Food Interactions
9 Disease Interactions
10 Technical Classification
11 Available Alternatives
- 11.1 What are the commonly available Substitutes?
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Overview

ZYLOPRED 0.3% W/V/0.5% W/V EYE DPS is a Schedule H drug.

ZYLOPRED 0.3% W/V/0.5% W/V EYE DPS is composed of: GEFITINIB (0.3 %W/V), LOTEPREDNOL (0.5 %W/V)

Gefitinib is used to treat non-small cell lung cancer. Gefitinib is a cancer medication that interferes with the growth and spread of cancer cells in the body. Gefitinib belongs to a group of drugs called epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors.

Loteprednol is a steroid. It prevents the release of substances in the body that cause inflammation.Loteprednol ophthalmic (for the eye) is used to treat eye swelling caused by surgery, infection, allergies, and other conditions.

Usage

GEFITINIB is generally used to treat: Lung Cancer

LOTEPREDNOL is generally used to treat: Conjunctivitis, Edema, Iritis, Keratitis, Rosacea
LOTEPREDNOL can address symptoms like: Eyes Swelling, Eyes Pain

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Ask your doctor

Q: Can it be taken during pregnancy?
A: Studies indicate Risk – Doctor advice is must

Precautions

Before using this medication, ask your doctor or pharmacist about your medical history, especially of lung disease, severe kidney disease, eye problems, stomach/intestinal ulcers, other stomach/intestinal problems, smoking, cancer that has spread to the bowels.
Do not take gefitinib if you are allergic to any of its ingredients.
Before starting gefitinib treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.). Do not take aspirin, or products containing aspirin unless your doctor specifically permits this.
Do not receive any kind of immunization or vaccination without your doctor’s approval while taking gefitinib.
For both men and women: Do not conceive a child (get pregnant) while taking gefitinib. Barrier methods of contraception, such as condoms, are recommended. Discuss with your doctor when you may safely become pregnant or conceive a child after therapy.

You should not use this medicine if you are allergic to loteprednol or other steroids, or if you have any type of fungal, viral, or bacterial infection of your eye (including herpes or chickenpox).
Do not touch the tip of the eye dropper or place it directly on your eye. A contaminated dropper can infect your eye, which could lead to serious vision problems.Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.
Do not use loteprednol for longer than 2 weeks unless your doctor tells you to.
Do not use this medication while wearing contact lenses. Loteprednol may contain a preservative that can discolor soft contact lenses. Wait at least 10 minutes after using the eye drops before putting in your contact lenses.
If you use loteprednol ophthalmic gel, do not wear contacts at all throughout your treatment with the gel.
Shake the eye drops well just before each use. If using the gel, turn the bottle upside down and shake once to fill the dropper tip with gel.
Wash your hands before using the eye drops.
Do not use the eye drops if the liquid has changed colors or has particles in it.
Do not use extra medicine to make up the missed dose.
Do not use other eye medications unless your doctor tells you to.It may cause blurred vision, do not drive a car or operate machinery while taking this medication.
May require frequent follow-ups with the doctor to monitor side effects.
Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution.
Take with food to avoid an upset stomach.
Dose is decreased or tapered over time.

Common Side-Effects

GEFITINIB : Eyes Burning Sensation, Chest Pain, Chills, Cough, Difficulty Breathing, Eyes Dry Eyes, Shortness Of Breath
LOTEPREDNOL : Eyes Dry Eyes, Eyes Burn, Eyes Itching, Eyes Redness, Eyes Watery Eyes, Eyes Sensitive To Light, Head Headache, Runny Nose, Throat Soreness, Eyes Swelling, Eyes Pain, Eyes Discomfort, Eyes Discharge Or Mucus, Eyes Eye Irritation, Eyelids Redness

Serious Side-Effects

GEFITINIB : Abdomen Pain, Dark Colored (brown) Urine, Decreased Appetite, Fever, Nausea, Vomit
LOTEPREDNOL : Glaucoma, Vision Problems, Eyes Blurred Vision, Eyes Change In Vision

Rare Side-Effects

GEFITINIB : Bloody Or Red Colored Stools, Eyes Redness, Eyes Eye Irritation, Heartburn, Abdomen Pain, Throat Soreness, Vomit

Food Interactions

Grapefruit may increase serum product levels.

Disease Interactions

LOTEPREDNOL can interfere with: Glaucoma

Technical Classification

GEFITINIB is categorized as: EGFR INHIBITORS / ANTINEOPLASTICS
LOTEPREDNOL is categorized as: OPHTHALMIC STEROIDS / OPHTHALMIC PREPARATIONS / TOPICAL AGENTS

Available Alternatives

What are the commonly available Substitutes?

LOTEGATE EYE DPS	INR 117 for 5 ML EYE DROP	LOTEPREDNOL 500.0 MG, GEFITINIB 3.0 MG
ZYLOPRED 0.3% W/V/0.5% W/V EYE DPS	INR 190.28 for 5 ML EYE DROP	GEFITINIB 0.3 %W/V, LOTEPREDNOL 0.5 %W/V