AXITINIB

Overview

AXITINIB is an Over-the-counter (OTC) drug.
Axitinib interferes with the growth of some cancer cells. Axitinib is a targeted therapy and is a receptor protein-kinase inhibitor. It inhibits the actions of vascular growth factor (VEGF)  is an angiogenesis inhibitor and which work by blocking the action of an abnormal protein that signals cancer cells to multiply. Axitinib treats cancer of the kidneys. Axitinib can cause diarrhea and increased blood pressure. Blood pressure should be monitored regularly during treatment.

Usage

AXITINIB is generally used to treat: Kidney Cancer, Renal Cell Carcinoma

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Ask your doctor

Q: Can it be taken during pregnancy?
A: Studies indicate Risk – Doctor advice is must

How Do I Take It?

Route of Administration: Oral

Precautions

• High blood pressure (hypertension). Your doctor should check your blood pressure regularly during treatment with axitinib. If you develop blood pressure problems, your doctor may prescribe medicine to treat your high blood pressure, lower your dose, or stop your treatment with axitinib.
• Do not take axitinib if you are allergic to any of its ingredients.
• Bleeding: Axinitib can cause bleeding which can be serious, and sometimes lead to death. Call your doctor or get medical help if you develop any bleeding.
• take care if you have tear in your stomach or intestinal wall (perforation)
• Reversible Posterior Leukoencephalopathy Syndrome (RPLS). A condition called reversible posterior leukoencephalopathy syndrome (RPLS) can happen while taking axitinib.
• If you develop protein in your urine, your doctor may decrease your dose of axitinib or stop your treatment.

Symptoms of Overdosage

AXITINIB over-dosage can result in: Seizures (uncontrollable Jerking Of Limbs), Dizziness, Head Headache, Vomit

Common Side-Effects

AXITINIB : Seizure, Anxiety, Abdomen Pain, Gums Bleeding, Eyes Blurred Vision, Cloudy Urine With Strong Odor, Confusion, Constipation, Cough, Decreased Urination, Depressed Mood, Difficulty Breathing, Difficulty Swallowing, Dizziness, Dry Mouth, Fainting, Hair Loss, Hoarse Voice, Slurred Speech, Vagina Bleeding, Frequent Urination, Lightheadedness, Loss Of Appetite, Nausea, Nervousness, Rapid Breathing, Black (tar) Colored Stools, Dark Colored (brown) Urine, Slow Heart Rate (pulse), Eyes Sunken Eyes, Increased Thirst, Hands Tingling, Feet Tingling, Weakness (generalized), Vomit, Weight Gain, Weight Loss (unintentional)

Rare Side-Effects

AXITINIB : Gums Bleeding, Black (tar) Colored Stools, Eyes Change In Vision, Chest Pain, Heartburn, Drowsiness, Eyes Pain, Face Numbness, Hands Numbness, Legs Numbness, Arms Pain, Jaws Pain, Neck Pain, Arms Swelling, Legs Swelling, Pale Skin, Ringing In Ears, Increased Sensitivity To Heat, Head Headache, Abdomen Pain, Abdomen Stomach Cramps, Slurred Speech, Loss Of Coordination, Slow Or Irregular Breathing, Eyes Blindness, Difficulty Sleeping, Anus Swelling, Vomit

Food Interactions

Avoid combination with strong CYP3A4 inhibitors such as grapefruit juice due to the likely increased levels of axitinib. If the combination cannot be avoided, reduce axitinib dose by 50%.

Disease Interactions

AXITINIB can interfere with: Proteinuria, Hypertension, Thromboembolism

Technical Classification

AXITINIB is categorized as:

• MULTIKINASE INHIBITORS / ANTINEOPLASTICS
• VEGF/VEGFR INHIBITORS / ANTINEOPLASTICS

Storage Conditions

Room Temperature (Between 15 To 25 C)

Available Alternatives

Common Drugs with AXITINIB as Ingredient

INLYTA 5MG TAB

AXITINIB 5 MG