BOSENTAN

Overview

BOSENTAN is an Over-the-counter (OTC) drug.
Bosentan treats high blood pressure in the lungs. Can cause fluid retention and swelling of your ankles and legs.Bosentan is a prescription medication used to treat high blood pressure in the vessels of the lungs, known medically as pulmonary arterial hypertension (PAH) in adults and pediatric patients aged 3 years and older. Bosentan belongs to a group of drugs called endothelin receptor antagonists, which help blood vessels to relax, lowering blood pressure and allowing the heart to pump blood more efficiently.

Usage

BOSENTAN is generally used to treat: Pulmonary Heart Disease

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Not Safe

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Ask your doctor

Q: Can it be taken during pregnancy?
A: Dangerous – Studies indicate Human-Fetal Risk

Q: Is it safe to take for someone breastfeeding?
A: Not Safe

How Do I Take It?

Route of Administration: Oral

Precautions

  • Liver problems may occur while you are using this medicine. Stop using this medicine and check with your doctor right away if you are having more than one of these symptoms are dark urine, fever with or without chills, light colored stools, loss of appetite, nausea and vomiting, skin rash, stomach pain, unusual tiredness, or yellow eyes or skin.
  • Bosentan may decrease the amount of sperm men make and affect their ability to have children. If you plan to have children, talk with your doctor before using this medicine.
  • This medicine may cause fluid retention (edema) in some patients. Check with your doctor right away if you are gaining weight rapidly, have swelling in your hands, ankles, feet, or all over the body or if you have trouble with breathing while you are using this medicine.
  • Pulmonary edema may occur while using this medicine. Stop using this medicine and check with your doctor right away if you have chest pain, noisy breathing, sometimes with wheezing, blue lips and fingernails, pale skin, increased sweating, coughing that sometimes produces a pink frothy sputum, or shortness of breath.
  • Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. 

Symptoms of Overdosage

BOSENTAN over-dosage can result in: Head Headache, Dizziness, Nausea, Vomit

Common Side-Effects

BOSENTAN : Sinusitis, Upper Respiratory Tract Infections, Eyes Blurred Vision, Confusion, Dizziness, Dark Colored (brown) Urine, Fainting, Fever, Chills, Nausea, Head Headache

Serious Side-Effects

BOSENTAN : Anxiety, Jaundice, Legs Swelling, Ankles Swelling, Pale Skin, Shortness Of Breath, Rapid Breathing, Irregular Heartbeat, Difficulty Concentrating, Head Headache, Nausea, Vomit, Fever, Upper Abdomen Pain, Fatigue (tiredness), Loss Of Appetite, Dark Colored (brown) Urine, Change In Stools, Wheezing, Cough, Chest Pain

Food Interactions

Grapefruit juice increases the concentration of bosentan in the body leading to side effects like nausea, vomiting, headache and liver problems.

Disease Interactions

BOSENTAN can interfere with: Acute Liver Failure, Anemia, Acute Kidney Failure

Technical Classification

BOSENTAN is categorized as: AGENTS FOR PULMONARY HYPERTENSION / CARDIOVASCULAR AGENTS

Storage Conditions

Room Temperature (Between 15 To 25 C)

Available Alternatives

Common Drugs with BOSENTAN as Ingredient

BOSENAT 62.5MG TABBOSENTAN 62.5 MG
BOSENTAS 125MG TABBOSENTAN 125.0 MG
BOSENTAS 62.5MG TABBOSENTAN 62.5 MG
BOZETAN 125MG TABBOSENTAN 125.0 MG
LUPIBOSE 62.5MG TABBOSENTAN 62.5 MG