CLOZAPINE

Overview

CLOZAPINE is a Schedule H drug.
Clozapine is an antipsychotic medication. It works by changing the actions of chemicals in the brain. Clozapine is used to treat severe schizophrenia, or to reduce the risk of suicidal behavior in people with schizophrenia or similar disorders. Clozapine is an atypical antipsychotic. It works by modulating the action of certain chemical messengers in the brain that affect thoughts. Clozapine is in a class of medications called atypical antipsychotics. It works by changing the activity of certain natural substances in the brain.

Usage

CLOZAPINE is generally used to treat: Schizophrenia, Manic Depression, Bipolar
CLOZAPINE can address symptoms like: Hallucinations, Socially Withdrawn, Memory Problems, Slurred Speech, Unusual Facial Expression

Frequently Asked Questions

Q: Is it safe on my liver?
A: Not Safe

Q: Is it safe on my kidney?
A: Check with your Doctor first

Q: Can I take it with alcohol?
A: Not Safe

Q: Is it safe for children?
A: Not Advised for age < 18yrs

Q: Can it be taken during pregnancy?
A: Considered as Generally Safe – not enough studies to prove risk

How Do I Take It?

Route of Administration: Oral

Precautions


  • inform your doctor before taking the medicine if you have kidney, liver or heart disease, prostate problem, difficulty in passing urine, diabetes or elevated blood sugar levels, chronic constipation, glaucoma, blood clots or history of blood clots, epilepsy, galactose intolerance or Lapp lactase deficiency, diseases of the large intestine, heart problems (problems with QT interval), or if you have risk factors for stroke (high blood pressure or problems in the blood vessels of the brain), or if you have had an abdominal surgery in the past.
  •  Do not drive or operate heavy machinery and be careful while getting up from a sitting or lying position after taking clozapine as it may make you feel dizzy.
  •  Always ensure you are being regularly monitored for white blood cell count, total blood cell count, heart rate (ECG), liver function, and lipid function by taking appropriate tests.
  •  Avoid smoking, regular caffeine intake, and alcohol while taking this medicine, as it may worsen the side effects.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.
  • Clozapine is not approved for use in psychotic conditions related to dementia. This medicine may increase the risk of death in older adults with dementia-related conditions.
  • You should not take clozapine if you have ever developed a severe infection or severe allergic reaction while taking this medicine.
  • Clozapine is not approved for use in psychotic conditions related to dementia. Clozapine may increase the risk of death in older adults with dementia-related conditions.
  • Take clozapine exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Symptoms of Overdosage

CLOZAPINE over-dosage can result in: Difficulty Breathing

Common Side-Effects

CLOZAPINE : Febrile Convulsions, Anxiety, Hyperventilation, Bladder Control, Loss Of, Ulcer, Stomach, Fever, Hypotension, Tachycardia, Chest Pain, Chills, Black (tar) Colored Stools, Cough, Dry Mouth, Head Headache, Restless Or Irritability, Throat Soreness, Slurred Speech, Lower Back Pain

Serious Side-Effects

CLOZAPINE : Dizziness, Irregular Heartbeat, Fainting, Fever, Eyes Blurred Vision, Confusion, Fainting, Body Excessive Sweating, Lightheadedness, Weakness (generalized), Legs Shaking, Hands Shaking

Rare Side-Effects

CLOZAPINE : Cardiac Arrest, Hypercholesterolemia, Hyperglycemia, Diabetic Ketoacidosis, Delirium, Sudden Cardiac Death, Anemia, Impotence, Hepatitis, Lower Respiratory Tract Infections, Decreased Appetite, Increased Thirst, Dark Colored (brown) Urine, Nausea, Vomit, Eyes Discoloration, Body Discoloration, Legs Swelling, Pale Skin

Food Interactions

Avoid drinking caffeinated beverages.

Disease Interactions

CLOZAPINE can interfere with: Dementia, Hepatitis, Tardive Dyskinesia, Seizure, Hyperglycemia, Hypotension, Thromboembolism, Hyperprolactinaemia, Parkinsonism

Technical Classification

CLOZAPINE is categorized as: ATYPICAL ANTIPSYCHOTICS / ANTIPSYCHOTICS / PSYCHOTHERAPEUTIC AGENTS

Storage Conditions

Room Temperature (Between 15 To 25 C)

Available Alternatives

Common Drugs with CLOZAPINE as Ingredient

ALKEPIN ODT 100MG TABCLOZAPINE 100.0 MG
ALKEPIN ODT 12.5MG TABCLOZAPINE 12.5 MG
ALKEPIN ODT 200MG TABCLOZAPINE 200.0 MG
ALKEPIN ODT 25MG TABCLOZAPINE 25.0 MG
ALKEPIN ODT 50MG TABCLOZAPINE 50.0 MG
CHROZAP 100MG TABCLOZAPINE 100.0 MG
CHROZAP TABCLOZAPINE
CIPIN 100MG TABCLOZAPINE 100.0 MG
CIPIN 200MG TABCLOZAPINE 200.0 MG
CIPIN 25MG TABCLOZAPINE 25.0 MG
CIPIN 50MG TABCLOZAPINE 50.0 MG
CLOCER 100MG TABCLOZAPINE 100.0 MG
CLOCER 25MG TABCLOZAPINE 25.0 MG
CLOCER 50MG TABCLOZAPINE 50.0 MG
CLOMACH 100MG TABCLOZAPINE 100.0 MG
CLOMACH 25MG TABCLOZAPINE 25.0 MG
CLOMACH 50MG TABCLOZAPINE 50.0 MG
CLONEX 100MG TABCLOZAPINE 100.0 MG
CLONEX 25MG TABCLOZAPINE 25.0 MG
CLONEX 50MG TABCLOZAPINE 50.0 MG
CLOSIN 100MG TABCLOZAPINE 100.0 MG
CLOSIN 25MG TABCLOZAPINE 25.0 MG
CLOSIN 50MG TABCLOZAPINE 50.0 MG
CLOZABEST 25MG TABCLOZAPINE 25.0 MG
CLOZABEST 50MG TABCLOZAPINE 50.0 MG
CLOZAP 0.5MG TABCLOZAPINE 0.5 MG
CLOZAP 2MG TABCLOZAPINE 2.0 MG
COZAPINE 100MG TABCLOZAPINE 100.0 MG
COZAPINE 25MG TABCLOZAPINE 25.0 MG
COZAPINE 50MG TABCLOZAPINE 50.0 MG
KLOZA 100MG TABCLOZAPINE 100.0 MG
KLOZA 25MG TABCLOZAPINE 25.0 MG
KLOZA 50MG TABCLOZAPINE 50.0 MG
LOZAPIN 100MG TABCLOZAPINE 100.0 MG
LOZAPIN 25MG TABCLOZAPINE 25.0 MG
LOZAPIN 50MG TABCLOZAPINE 50.0 MG
NEUROPIN 100MG TABCLOZAPINE 100.0 MG
NEUROPIN 25MG TABCLOZAPINE 25.0 MG
NEUROPIN 50MG TABCLOZAPINE 50.0 MG
PSYCLO 100MG TABCLOZAPINE 100.0 MG
PSYCLO 25MG TABCLOZAPINE 25.0 MG
PSYCLO 50MG TABCLOZAPINE 50.0 MG
PYNE 25MG TABCLOZAPINE 25.0 MG
REFRACT 100MG TABCLOZAPINE 100.0 MG
REFRACT 25MG TABCLOZAPINE 25.0 MG
REFRACT 50MG TABCLOZAPINE 50.0 MG
SIZEP 100MG TABCLOZAPINE 100.0 MG
SIZEP 25MG TABCLOZAPINE 25.0 MG
SIZEP 50MG TABCLOZAPINE 50.0 MG
SIZOLAM 100MG TABCLOZAPINE 100.0 MG
SIZOLAM 25MG TABCLOZAPINE 25.0 MG
SIZOPIN 100MG TABCLOZAPINE 100 MG
SIZOPIN 200MG TABCLOZAPINE 200.0 MG
SIZOPIN 25MG TABCLOZAPINE 25 MG
SIZOPIN 50MG TABCLOZAPINE 50 MG
SKIZORIL 100MG TABCLOZAPINE 100.0 MG
SKIZORIL 200MG TABCLOZAPINE 200.0 MG
SKIZORIL 25MG TABCLOZAPINE 25.0 MG
SKIZORIL 50MG TABCLOZAPINE 50 MG
SOLOQUIN 25MG TABCLOZAPINE 25.0 MG
SYCLOP 100MG TABCLOZAPINE 100.0 MG
SYZOPIN 100MG TABCLOZAPINE 100.0 MG
SYZOPIN 25MG TABCLOZAPINE 25.0 MG
SYZOPIN 50MG TABCLOZAPINE 50.0 MG
VAROZAP 100MG TABCLOZAPINE 100.0 MG
VAROZAP 50MG TABCLOZAPINE 50.0 MG
VIZONIC 100MG TABCLOZAPINE 100.0 MG
VIZONIC 25MG TABCLOZAPINE 25.0 MG
VIZONIC 50MG TABCLOZAPINE 50.0 MG
VIZOPIN 100MG TABCLOZAPINE 100.0 MG
VIZOPIN 25MG TABCLOZAPINE 25.0 MG
VIZOPIN 50MG TABCLOZAPINE 50.0 MG
ZAPORIL 100MG TABCLOZAPINE 100.0 MG
ZAPORIL 12.5MG TABCLOZAPINE 12.5 MG
ZAPORIL 200MG TABCLOZAPINE 200.0 MG
ZAPORIL 25MG TABCLOZAPINE 25.0 MG
ZAPORIL 50MG TABCLOZAPINE 50.0 MG
ZOPIN 100MG TABCLOZAPINE 100.0 MG
ZOPIN 50MG TABCLOZAPINE 50.0 MG
ZOPIN LTNCLOZAPINE
ZOPIZONE 100MG TABCLOZAPINE 100.0 MG
ZOPIZONE 25MG TABCLOZAPINE 25.0 MG
ZOPIZONE 50MG TABCLOZAPINE 50.0 MG